SLITRK4 (SLIT and NTRK like family member 4) - Rat Genome Database

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Gene: SLITRK4 (SLIT and NTRK like family member 4) Pan paniscus
Analyze
Symbol: SLITRK4
Name: SLIT and NTRK like family member 4
RGD ID: 11752980
Description: INVOLVED IN axonogenesis (ortholog); positive regulation of synapse assembly (ortholog); ASSOCIATED WITH autistic disorder (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: SLIT and NTRK-like protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X143,039,708 - 143,053,417 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X143,043,310 - 143,057,016 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X132,750,454 - 132,763,782 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X143,132,733 - 143,146,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX143,138,515 - 143,141,028 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLITRK4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X143,039,708 - 143,053,417 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X143,043,310 - 143,057,016 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X132,750,454 - 132,763,782 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X143,132,733 - 143,146,029 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX143,138,515 - 143,141,028 (-)Ensemblpanpan1.1panPan2
SLITRK4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X143,622,790 - 143,636,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX143,622,790 - 143,636,101 (-)EnsemblGRCh38hg38GRCh38
GRCh37X142,710,595 - 142,723,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X142,543,584 - 142,550,685 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X142,441,463 - 142,448,539NCBI
CeleraX142,997,864 - 143,011,197 (-)NCBICelera
Cytogenetic MapXq27.3NCBI
HuRefX131,814,638 - 131,827,586 (-)NCBIHuRef
CHM1_1X142,622,489 - 142,635,821 (-)NCBICHM1_1
T2T-CHM13v2.0X141,932,069 - 141,945,367 (-)NCBIT2T-CHM13v2.0
Slitrk4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X63,308,489 - 63,320,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX63,308,491 - 63,320,602 (-)EnsemblGRCm39 Ensembl
GRCm38X64,264,883 - 64,277,345 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX64,264,885 - 64,276,996 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X61,522,619 - 61,530,171 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X60,530,109 - 60,537,661 (-)NCBIMGSCv36mm8
CeleraX50,666,912 - 50,674,468 (-)NCBICelera
Cytogenetic MapXA7.1NCBI
cM MapX34.57NCBI
Slitrk4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X147,728,163 - 147,755,086 (-)NCBIGRCr8
mRatBN7.2X142,706,495 - 142,718,968 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX142,706,338 - 142,718,575 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX144,906,746 - 144,913,095 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X148,431,708 - 148,438,057 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X145,981,431 - 145,987,780 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X147,582,195 - 147,589,529 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X147,598,020 - 147,605,354 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X150,053,376 - 150,059,675 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX138,589,008 - 138,595,357 (-)NCBICelera
Cytogenetic MapXq36NCBI
Slitrk4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555391,929,681 - 1,942,525 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555391,929,681 - 1,942,525 (-)NCBIChiLan1.0ChiLan1.0
SLITRK4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X112,794,049 - 112,806,710 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX112,799,447 - 112,801,963 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX98,633,819 - 98,646,492 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X114,805,470 - 114,818,159 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX114,809,815 - 114,818,165 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X111,922,592 - 111,935,261 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X114,135,361 - 114,148,018 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X113,786,520 - 113,799,188 (-)NCBIUU_Cfam_GSD_1.0
Slitrk4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X110,858,763 - 110,871,727 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365134,743,661 - 4,750,633 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365134,742,743 - 4,750,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLITRK4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX117,148,744 - 117,156,801 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X117,145,647 - 117,157,275 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X133,678,389 - 133,687,860 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLITRK4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X118,508,790 - 118,518,971 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX118,511,438 - 118,513,951 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606555,904,351 - 55,917,649 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slitrk4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248083,516,092 - 3,523,455 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248083,516,053 - 3,527,915 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000014619   ⟹   ENSPPAP00000003162
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX143,138,515 - 143,141,028 (-)Ensembl
RefSeq Acc Id: XM_003816808   ⟹   XP_003816856
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X143,039,708 - 143,053,417 (-)NCBI
NHGRI_mPanPan1X143,043,310 - 143,057,016 (-)NCBI
Mhudiblu_PPA_v0X132,750,454 - 132,763,782 (-)NCBI
PanPan1.1X143,132,733 - 143,146,029 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003816809   ⟹   XP_003816857
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X143,039,708 - 143,052,048 (-)NCBI
NHGRI_mPanPan1X143,043,310 - 143,055,623 (-)NCBI
Mhudiblu_PPA_v0X132,750,454 - 132,762,875 (-)NCBI
PanPan1.1X143,132,733 - 143,145,136 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003816810   ⟹   XP_003816858
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X143,039,708 - 143,051,655 (-)NCBI
NHGRI_mPanPan1X143,043,310 - 143,055,210 (-)NCBI
Mhudiblu_PPA_v0X132,750,454 - 132,762,352 (-)NCBI
PanPan1.1X143,132,733 - 143,144,418 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004668929
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X143,039,708 - 143,051,655 (-)NCBI
NHGRI_mPanPan1X143,043,310 - 143,055,210 (-)NCBI
Mhudiblu_PPA_v0X132,750,454 - 132,762,352 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003816856 (Get FASTA)   NCBI Sequence Viewer  
  XP_003816857 (Get FASTA)   NCBI Sequence Viewer  
  XP_003816858 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000003162.1
Reference Protein Sequences
RefSeq Acc Id: XP_003816856   ⟸   XM_003816808
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZDQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816857   ⟸   XM_003816809
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZDQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816858   ⟸   XM_003816810
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000003162   ⟸   ENSPPAT00000014619
Protein Domains
LRRCT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000013354 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000014619.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  Slitrk UniProtKB/TrEMBL
KEGG Report pps:100988349 UniProtKB/TrEMBL
NCBI Gene SLITRK4 ENTREZGENE
PANTHER PTHR45773 UniProtKB/TrEMBL
  SLIT AND NTRK-LIKE PROTEIN 4 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A2R8ZDQ2 ENTREZGENE, UniProtKB/TrEMBL