RASL12 (RAS like family 12) - Rat Genome Database

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Gene: RASL12 (RAS like family 12) Pan paniscus
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Symbol: RASL12
Name: RAS like family 12
RGD ID: 11750956
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); nucleotide binding (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); diarrhea (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-like protein family member 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21654,299,467 - 54,314,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,470,679 - 58,485,371 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01543,992,879 - 44,007,564 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11562,277,131 - 62,292,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1562,277,131 - 62,300,660 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
RASL12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21654,299,467 - 54,314,128 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11558,470,679 - 58,485,371 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01543,992,879 - 44,007,564 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11562,277,131 - 62,292,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1562,277,131 - 62,300,660 (-)Ensemblpanpan1.1panPan2
RASL12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381565,045,580 - 65,076,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1565,053,337 - 65,076,690 (-)EnsemblGRCh38hg38GRCh38
GRCh371565,345,675 - 65,369,005 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361563,132,728 - 63,147,441 (-)NCBINCBI36Build 36hg18NCBI36
Build 341563,132,729 - 63,147,441NCBI
Celera1542,223,841 - 42,238,547 (-)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1542,170,320 - 42,185,026 (-)NCBIHuRef
CHM1_11565,465,460 - 65,480,175 (-)NCBICHM1_1
T2T-CHM13v2.01562,855,016 - 62,886,085 (-)NCBIT2T-CHM13v2.0
Rasl12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39965,305,766 - 65,323,420 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl965,305,788 - 65,322,135 (+)EnsemblGRCm39 Ensembl
GRCm38965,398,485 - 65,416,138 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl965,398,506 - 65,414,853 (+)EnsemblGRCm38mm10GRCm38
MGSCv37965,246,295 - 65,262,660 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36965,196,544 - 65,210,704 (+)NCBIMGSCv36mm8
Celera962,628,261 - 62,644,544 (+)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.28NCBI
Rasl12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8874,813,000 - 74,827,041 (+)NCBIGRCr8
mRatBN7.2865,917,840 - 65,931,885 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl865,917,840 - 65,932,741 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx871,430,234 - 71,444,195 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0869,703,243 - 69,717,206 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0867,572,840 - 67,586,887 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0870,915,944 - 70,931,275 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl870,915,953 - 70,930,179 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0870,607,875 - 70,623,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4869,647,741 - 69,661,804 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1869,666,886 - 69,679,326 (+)NCBI
Celera865,315,599 - 65,329,634 (+)NCBICelera
Cytogenetic Map8q24NCBI
Rasl12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545010,352,574 - 10,363,906 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545010,352,574 - 10,363,906 (+)NCBIChiLan1.0ChiLan1.0
RASL12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13029,436,144 - 29,450,212 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3029,366,077 - 29,379,722 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03029,625,351 - 29,638,952 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3029,575,395 - 29,638,967 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13029,558,117 - 29,571,691 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03029,619,750 - 29,633,345 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03029,860,620 - 29,874,239 (-)NCBIUU_Cfam_GSD_1.0
Rasl12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640107,531,530 - 107,544,373 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647125,379,100 - 25,392,917 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647125,379,587 - 25,392,408 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RASL12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1163,089,444 - 163,103,523 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11163,089,440 - 163,104,027 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RASL12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12618,516,275 - 18,533,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2618,518,001 - 18,535,726 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048122,900,149 - 122,915,819 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rasl12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247817,430,793 - 7,442,614 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247817,430,693 - 7,442,687 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000039219   ⟹   ENSPPAP00000016521
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1562,277,131 - 62,292,055 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000039224   ⟹   ENSPPAP00000016527
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1562,277,131 - 62,292,047 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000039230   ⟹   ENSPPAP00000016533
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1562,278,695 - 62,300,660 (-)Ensembl
RefSeq Acc Id: XM_003827959   ⟹   XP_003828007
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21654,299,467 - 54,314,113 (-)NCBI
NHGRI_mPanPan11558,470,695 - 58,485,371 (-)NCBI
Mhudiblu_PPA_v01543,992,879 - 44,007,564 (-)NCBI
PanPan1.11562,277,131 - 62,292,055 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003827960   ⟹   XP_003828008
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21654,299,467 - 54,314,128 (-)NCBI
NHGRI_mPanPan11558,470,679 - 58,485,369 (-)NCBI
Mhudiblu_PPA_v01543,992,882 - 44,007,564 (-)NCBI
PanPan1.11562,277,131 - 62,292,047 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003828007 (Get FASTA)   NCBI Sequence Viewer  
  XP_003828008 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000016521
  ENSPPAP00000016521.1
  ENSPPAP00000016527
  ENSPPAP00000016527.1
  ENSPPAP00000016533.1
RefSeq Acc Id: XP_003828007   ⟸   XM_003827959
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AGQ4 (UniProtKB/TrEMBL),   A0A2R9AHP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003828008   ⟸   XM_003827960
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AGQ5 (UniProtKB/TrEMBL),   A0A2R9AHP2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000016533   ⟸   ENSPPAT00000039230
RefSeq Acc Id: ENSPPAP00000016527   ⟸   ENSPPAT00000039224
RefSeq Acc Id: ENSPPAP00000016521   ⟸   ENSPPAT00000039219


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031385 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039219.1 UniProtKB/TrEMBL
  ENSPPAT00000039224.1 UniProtKB/TrEMBL
  ENSPPAT00000039230.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
KEGG Report pps:100978875 UniProtKB/TrEMBL
NCBI Gene RASL12 ENTREZGENE
PANTHER PROTEIN CBG04185 UniProtKB/TrEMBL
  RAS-LIKE FAMILY MEMBER 11 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AGQ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AGQ5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AHP2 ENTREZGENE, UniProtKB/TrEMBL