PELO (pelota mRNA surveillance and ribosome rescue factor) - Rat Genome Database

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Gene: PELO (pelota mRNA surveillance and ribosome rescue factor) Pan paniscus
Analyze
Symbol: PELO
Name: pelota mRNA surveillance and ribosome rescue factor
RGD ID: 11747957
Description: ENCODES a protein that exhibits endonuclease activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN chromosome organization (ortholog); endoderm development (ortholog); inner cell mass cell proliferation (ortholog); PARTICIPATES IN translation termination pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pelota homolog; pelota homolog (Drosophila)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1562,851,499 - 62,865,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,851,099 - 62,865,786 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0561,229,841 - 61,247,565 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
PELO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1562,851,499 - 62,865,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl562,851,099 - 62,865,786 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0561,229,841 - 61,247,565 (-)NCBIMhudiblu_PPA_v0panPan3
PELO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38552,787,916 - 52,804,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl552,787,916 - 52,804,044 (+)EnsemblGRCh38hg38GRCh38
GRCh37552,083,750 - 52,099,878 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36552,119,531 - 52,134,208 (+)NCBINCBI36hg18NCBI36
Build 34552,119,530 - 52,134,206NCBI
Celera549,037,324 - 49,052,004 (+)NCBI
Cytogenetic Map5q11.2NCBI
HuRef549,055,620 - 49,070,302 (+)NCBIHuRef
CHM1_1552,086,424 - 52,101,104 (+)NCBICHM1_1
Pelo
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913115,224,891 - 115,226,694 (-)NCBIGRCm39mm39
GRCm39 Ensembl13115,224,891 - 115,226,722 (-)Ensembl
GRCm3813115,088,355 - 115,090,158 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13115,088,355 - 115,090,186 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713115,878,563 - 115,880,366 (-)NCBIGRCm37mm9NCBIm37
MGSCv3613116,209,242 - 116,211,703 (-)NCBImm8
Celera13119,447,710 - 119,449,318 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
Pelo
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2246,797,853 - 46,799,621 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl246,797,853 - 46,799,746 (-)Ensembl
Rnor_6.0247,266,758 - 47,268,526 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl247,266,738 - 47,268,625 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0271,808,491 - 71,810,259 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,900,723 - 45,902,491 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1245,828,956 - 45,830,724 (-)NCBI
Celera242,545,596 - 42,547,364 (-)NCBICelera
Cytogenetic Map2q14NCBI
Pelo
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544614,564,366 - 14,566,178 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544614,564,366 - 14,566,178 (-)NCBIChiLan1.0ChiLan1.0
PELO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1462,440,923 - 62,443,598 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha462,216,402 - 62,218,376 (-)NCBI
ROS_Cfam_1.0462,939,633 - 62,941,473 (-)NCBI
ROS_Cfam_1.0 Ensembl462,791,553 - 62,953,332 (-)Ensembl
UMICH_Zoey_3.1462,714,001 - 62,716,979 (-)NCBI
UNSW_CanFamBas_1.0462,831,158 - 62,834,996 (-)NCBI
UU_Cfam_GSD_1.0463,366,543 - 63,368,230 (-)NCBI
Pelo
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213205,642,223 - 205,644,180 (-)NCBI
SpeTri2.0NW_00493648014,578,718 - 14,580,690 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PELO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1632,142,034 - 32,148,335 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11632,130,254 - 32,146,114 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21633,953,117 - 33,955,102 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PELO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1449,094,330 - 49,097,545 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl449,094,528 - 49,100,838 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660822,036,319 - 2,040,892 (-)NCBIVero_WHO_p1.0
Pelo
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247596,525,529 - 6,527,320 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054985   ⟹   ENSPPAP00000032119
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl562,851,099 - 62,865,786 (-)Ensembl
RefSeq Acc Id: XM_008952724   ⟹   XP_008950972
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1562,851,667 - 62,865,786 (-)NCBI
Mhudiblu_PPA_v0561,229,841 - 61,247,565 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034960108   ⟹   XP_034815999
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0561,229,841 - 61,235,995 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008950972 (Get FASTA)   NCBI Sequence Viewer  
  XP_034815999 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008950972   ⟸   XM_008952724
- Sequence:
RefSeq Acc Id: XP_034815999   ⟸   XM_034960108
RefSeq Acc Id: ENSPPAP00000032119   ⟸   ENSPPAT00000054985
Protein Domains
eRF1_1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038951 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000032119 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054985 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.870 UniProtKB/TrEMBL
  3.30.1330.30 UniProtKB/TrEMBL
  3.30.420.60 UniProtKB/TrEMBL
InterPro eFR1_2_sf UniProtKB/TrEMBL
  eRF1_1_Pelota UniProtKB/TrEMBL
  eRF1_2 UniProtKB/TrEMBL
  eRF1_3 UniProtKB/TrEMBL
  L30e-like UniProtKB/TrEMBL
  Pelota/DOM34_N UniProtKB/TrEMBL
  Transl-rel_pelota UniProtKB/TrEMBL
KEGG Report pps:103783105 UniProtKB/TrEMBL
NCBI Gene PELO ENTREZGENE
PANTHER PTHR10853 UniProtKB/TrEMBL
Pfam eRF1_1 UniProtKB/TrEMBL
  eRF1_2 UniProtKB/TrEMBL
  eRF1_3 UniProtKB/TrEMBL
SMART eRF1_1 UniProtKB/TrEMBL
Superfamily-SCOP SSF159065 UniProtKB/TrEMBL
  SSF55315 UniProtKB/TrEMBL
TIGRFAMs pelota UniProtKB/TrEMBL
UniProt A0A2R9C046_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-13 PELO  pelota mRNA surveillance and ribosome rescue factor    pelota homolog (Drosophila)  Symbol and/or name change 5135510 APPROVED