LOC103785360 (neurotrophin-4) - Rat Genome Database

Name: LOC103785360
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: LOC103785360 (neurotrophin-4) Pan paniscus

Analyze

Symbol:

LOC103785360

Name:

neurotrophin-4

RGD ID:

11747103

Description:

ENCODES a protein that exhibits growth factor activity (inferred); signaling receptor binding (inferred); INVOLVED IN adult locomotory behavior (ortholog); epidermis development (ortholog); ganglion mother cell fate determination (ortholog); ASSOCIATED WITH asthma (ortholog); autistic disorder (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neurotrophin 4; NTF4

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NTF4 (neurotrophin 4)	NCBI	Ortholog
Mus musculus (house mouse):	Ntf5 (neurotrophin 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ntf4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ntf4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NTF4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ntf4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NTF4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NTF4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ntf4 (neurotrophin 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	54,994,710 - 55,010,424 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	54,995,009 - 54,995,641 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	46,041,053 - 46,041,808 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

asthma (ISO)

autistic disorder (ISO)

developmental and epileptic encephalopathy 12 (ISO)

genetic disease (ISO)

Glaucoma 1, Open Angle, O (ISO)

intellectual disability (ISO)

learning disability (ISO)

Memory Disorders (ISO)

Nerve Degeneration (ISO)

non-syndromic X-linked intellectual disability 99 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult locomotory behavior (ISO)

epidermis development (ISO)

ganglion mother cell fate determination (ISO)

innervation (ISO)

long-term memory (ISO)

mechanoreceptor differentiation (ISO)

negative regulation of cell death (ISO)

sensory organ boundary specification (ISO)

signal transduction (IEA)

taste bud development (ISO)

Cellular Component

extracellular region (IEA)

Molecular Function

growth factor activity (IEA)

protein binding (ISO)

signaling receptor binding (IEA)

References

Genomics

Comparative Map Data

LOC103785360
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	54,994,710 - 55,010,424 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	54,995,009 - 54,995,641 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	46,041,053 - 46,041,808 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

NTF4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,058,284 - 49,065,035 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	49,061,066 - 49,065,076 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	49,564,385 - 49,568,292 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,256,209 - 54,260,047 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	54,256,210 - 54,258,937	NCBI
Celera	19	46,431,605 - 46,435,443 (-)	NCBI
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	45,941,069 - 45,943,797 (-)	NCBI		HuRef
CHM1_1	19	49,566,638 - 49,569,366 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,055,917 - 52,059,823 (-)	NCBI

Ntf5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	45,063,119 - 45,066,603 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	45,063,119 - 45,066,603 (+)	Ensembl
GRCm38	7	45,413,695 - 45,417,179 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,413,695 - 45,417,179 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,669,065 - 52,672,549 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	45,281,737 - 45,285,221 (+)	NCBI			mm8
Celera	7	40,869,726 - 40,873,213 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.3	NCBI

Ntf4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	95,893,560 - 95,896,391 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	1	95,893,457 - 95,897,243 (+)	Ensembl
Rnor_6.0	1	101,405,314 - 101,408,145 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,405,314 - 101,408,145 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,484,724 - 102,487,555 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,885,577 - 95,888,408 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	95,963,687 - 95,966,519 (+)	NCBI
Celera	1	90,149,153 - 90,151,984 (+)	NCBI		Celera
RH 3.4 Map	1	909.3	RGD
Cytogenetic Map	1	q22	NCBI

Ntf4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,647,685 - 1,650,553 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,647,685 - 1,650,553 (+)	NCBI	ChiLan1.0	ChiLan1.0

NTF4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,371,335 - 107,377,238 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,371,335 - 107,376,987 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	1	107,895,849 - 107,901,840 (+)	NCBI
ROS_Cfam_1.0 Ensembl	1	107,895,849 - 107,901,548 (+)	Ensembl
UMICH_Zoey_3.1	1	107,563,703 - 107,569,398 (+)	NCBI
UNSW_CanFamBas_1.0	1	107,209,908 - 107,215,558 (+)	NCBI
UU_Cfam_GSD_1.0	1	108,045,520 - 108,051,170 (+)	NCBI

Ntf4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,398,887 - 21,401,144 (-)	NCBI
SpeTri2.0	NW_004936664	3,017,108 - 3,017,955 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NTF4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,271,246 - 54,274,092 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,271,244 - 54,288,846 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,039,657 - 50,057,398 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NTF4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,254,693 - 42,284,899 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	6	42,279,190 - 42,279,822 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666073	22,170,689 - 22,171,841 (-)	NCBI	Vero_WHO_p1.0

Ntf4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	5,007,801 - 5,008,451 (+)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624832	5,005,935 - 5,008,694 (+)	NCBI	HetGla_female_1.0		hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034945146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000024496 ⟹ ENSPPAP00000005402

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	54,995,009 - 54,995,641 (-)	Ensembl

RefSeq Acc Id:

XM_034945146 ⟹ XP_034801037

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
Mhudiblu_PPA_v0	19	46,041,053 - 46,041,808 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_034801037	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_034801037 ⟸ XM_034945146

RefSeq Acc Id:

ENSPPAP00000005402 ⟸ ENSPPAT00000024496

Protein Domains

NGF

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000022345	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000005402.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000024496.1	UniProtKB/TrEMBL
Gene3D-CATH	2.10.90.10	UniProtKB/TrEMBL
InterPro	Cystine-knot_cytokine	UniProtKB/TrEMBL
	Nerve_growth_factor-like	UniProtKB/TrEMBL
	Nerve_growth_factor-rel	UniProtKB/TrEMBL
	Nerve_growth_factor_CS	UniProtKB/TrEMBL
	Neurotrophin-4	UniProtKB/TrEMBL
NCBI Gene	NTF4	ENTREZGENE
PANTHER	PTHR11589	UniProtKB/TrEMBL
	PTHR11589:SF8	UniProtKB/TrEMBL
Pfam	NGF	UniProtKB/TrEMBL
PIRSF	NGF	UniProtKB/TrEMBL
PRINTS	NEUROTROPHN4	UniProtKB/TrEMBL
	NGF	UniProtKB/TrEMBL
PROSITE	NGF_1	UniProtKB/TrEMBL
SMART	NGF	UniProtKB/TrEMBL
Superfamily-SCOP	SSF57501	UniProtKB/TrEMBL
UniProt	A0A2R8ZKB9_PANPA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-07-01	LOC103785360	neurotrophin-4	NTF4	neurotrophin 4	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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