ZNFX1 (zinc finger NFX1-type containing 1) - Rat Genome Database

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Gene: ZNFX1 (zinc finger NFX1-type containing 1) Pan paniscus
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Symbol: ZNFX1
Name: zinc finger NFX1-type containing 1
RGD ID: 11741465
Description: ENCODES a protein that exhibits helicase activity (inferred); metal ion binding (inferred); RNA binding (inferred); INVOLVED IN activation of innate immune response (inferred); defense response to bacterium (inferred); defense response to virus (inferred); ASSOCIATED WITH developmental and epileptic encephalopathy 26 (ortholog); genetic disease (ortholog); IMMUNODEFICIENCY 91 AND HYPERINFLAMMATION (ortholog); FOUND IN cytoplasmic stress granule (ortholog); mitochondrial outer membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NFX1-type zinc finger-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22154,988,056 - 55,020,345 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12054,981,159 - 55,013,496 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02045,585,137 - 45,616,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12046,649,050 - 46,681,289 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2046,642,081 - 46,681,289 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZNFX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22154,988,056 - 55,020,345 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12054,981,159 - 55,013,496 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02045,585,137 - 45,616,769 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12046,649,050 - 46,681,289 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2046,642,081 - 46,681,289 (-)Ensemblpanpan1.1panPan2
ZNFX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382049,245,900 - 49,278,057 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2049,237,946 - 49,278,426 (-)EnsemblGRCh38hg38GRCh38
GRCh372047,862,437 - 47,894,594 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362047,295,844 - 47,328,163 (-)NCBINCBI36Build 36hg18NCBI36
Celera2044,567,051 - 44,599,361 (-)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2044,611,201 - 44,643,138 (-)NCBIHuRef
CHM1_12047,766,837 - 47,799,145 (-)NCBICHM1_1
T2T-CHM13v2.02051,015,403 - 51,047,555 (-)NCBIT2T-CHM13v2.0
Znfx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392166,877,713 - 166,904,926 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2166,877,713 - 166,904,935 (-)EnsemblGRCm39 Ensembl
GRCm382167,035,790 - 167,063,015 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2167,035,793 - 167,063,015 (-)EnsemblGRCm38mm10GRCm38
MGSCv372166,861,293 - 166,888,515 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362166,726,998 - 166,754,970 (-)NCBIMGSCv36mm8
Celera2172,975,800 - 173,003,017 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map287.22NCBI
Znfx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83176,183,111 - 176,210,812 (-)NCBIGRCr8
mRatBN7.23155,764,073 - 155,791,777 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3155,764,980 - 155,821,242 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3159,565,363 - 159,593,055 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03168,064,336 - 168,092,028 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03165,806,044 - 165,833,738 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03163,787,101 - 163,847,671 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3163,787,101 - 163,847,671 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03169,947,421 - 170,007,642 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43158,187,092 - 158,246,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13158,093,125 - 158,152,983 (-)NCBI
Celera3154,352,937 - 154,405,628 (-)NCBICelera
Cytogenetic Map3q42NCBI
Znfx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554458,854,610 - 8,879,821 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554458,854,539 - 8,879,822 (+)NCBIChiLan1.0ChiLan1.0
ZNFX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12435,932,037 - 35,954,170 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2435,932,523 - 35,954,170 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2435,174,773 - 35,198,816 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02436,637,026 - 36,661,071 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2436,637,026 - 36,661,071 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12435,877,486 - 35,901,505 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02436,012,128 - 36,036,196 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02436,553,609 - 36,577,723 (-)NCBIUU_Cfam_GSD_1.0
Znfx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640189,511,167 - 189,536,973 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365144,966,172 - 4,988,922 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365144,964,844 - 4,992,004 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNFX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1750,925,791 - 50,958,705 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11750,925,789 - 50,958,722 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21757,190,106 - 57,222,272 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZNFX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1214,708,416 - 14,740,061 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605063,197,870 - 63,230,152 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znfx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247906,078,565 - 6,102,715 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247906,075,202 - 6,103,736 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000040868   ⟹   ENSPPAP00000018139
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2046,642,081 - 46,678,697 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000040885   ⟹   ENSPPAP00000018156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2046,649,050 - 46,681,289 (-)Ensembl
RefSeq Acc Id: XM_003809264   ⟹   XP_003809312
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22154,988,056 - 55,020,324 (-)NCBI
NHGRI_mPanPan12054,981,159 - 55,013,496 (-)NCBI
Mhudiblu_PPA_v02045,585,137 - 45,616,769 (-)NCBI
PanPan1.12046,649,050 - 46,681,289 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008961467   ⟹   XP_008959715
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22154,988,056 - 55,020,345 (-)NCBI
NHGRI_mPanPan12054,981,159 - 55,013,451 (-)NCBI
Mhudiblu_PPA_v02045,585,888 - 45,616,511 (-)NCBI
PanPan1.12046,650,418 - 46,681,024 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008961469   ⟹   XP_008959717
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22154,988,056 - 55,020,087 (-)NCBI
NHGRI_mPanPan12054,981,159 - 55,013,245 (-)NCBI
Mhudiblu_PPA_v02045,585,888 - 45,616,470 (-)NCBI
PanPan1.12046,650,418 - 46,681,024 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055104856   ⟹   XP_054960831
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22154,988,056 - 55,020,087 (-)NCBI
NHGRI_mPanPan12054,981,159 - 55,013,140 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003809312 (Get FASTA)   NCBI Sequence Viewer  
  XP_008959715 (Get FASTA)   NCBI Sequence Viewer  
  XP_008959717 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960831 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000018139.1
  ENSPPAP00000018156
  ENSPPAP00000018156.1
RefSeq Acc Id: XP_003809312   ⟸   XM_003809264
- UniProtKB: A0A2R9ALB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008959717   ⟸   XM_008961469
- UniProtKB: A0A2R9ALB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008959715   ⟸   XM_008961467
- UniProtKB: A0A2R9ALB5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000018139   ⟸   ENSPPAT00000040868
RefSeq Acc Id: ENSPPAP00000018156   ⟸   ENSPPAT00000040885
RefSeq Acc Id: XP_054960831   ⟸   XM_055104856
- UniProtKB: A0A2R9ALB5 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032191 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040868.1 UniProtKB/TrEMBL
  ENSPPAT00000040885.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  DNA2/NAM7-like UniProtKB/TrEMBL
  DNA2/NAM7-like_C UniProtKB/TrEMBL
  DNA2/NAM7_AAA_11 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  SF1_C_Upf1 UniProtKB/TrEMBL
  ZF_RZ_dom UniProtKB/TrEMBL
  Znf_NFX1 UniProtKB/TrEMBL
KEGG Report pps:100983140 UniProtKB/TrEMBL
NCBI Gene ZNFX1 ENTREZGENE
PANTHER NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  PTHR10887 UniProtKB/TrEMBL
Pfam AAA_11 UniProtKB/TrEMBL
  AAA_12 UniProtKB/TrEMBL
  DUF6539 UniProtKB/TrEMBL
PROSITE ZF_RZ UniProtKB/TrEMBL
SMART ZnF_NFX UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9ALB5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ATC6_PANPA UniProtKB/TrEMBL