MED23 (mediator complex subunit 23) - Rat Genome Database

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Gene: MED23 (mediator complex subunit 23) Pan paniscus
Analyze
Symbol: MED23
Name: mediator complex subunit 23
RGD ID: 11740565
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN positive regulation of gene expression (ortholog); positive regulation of T cell extravasation (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autosomal recessive intellectual developmental disorder 18 (ortholog); Fraser syndrome 3 (ortholog); genetic disease (ortholog); FOUND IN nucleus (ortholog); ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mediator of RNA polymerase II transcription subunit 23
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25151,592,256 - 151,634,143 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16149,498,888 - 149,540,825 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06129,386,301 - 129,428,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16133,493,587 - 133,535,337 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6133,481,115 - 133,535,988 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MED23
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25151,592,256 - 151,634,143 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16149,498,888 - 149,540,825 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06129,386,301 - 129,428,120 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16133,493,587 - 133,535,337 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6133,481,115 - 133,535,988 (-)Ensemblpanpan1.1panPan2
MED23
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386131,573,966 - 131,628,313 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6131,573,966 - 131,628,242 (-)EnsemblGRCh38hg38GRCh38
GRCh376131,895,106 - 131,949,453 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366131,936,799 - 131,991,056 (-)NCBINCBI36Build 36hg18NCBI36
Build 346131,936,799 - 131,991,056NCBI
Celera6132,641,744 - 132,696,002 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6129,476,289 - 129,531,194 (-)NCBIHuRef
CHM1_16132,158,892 - 132,213,170 (-)NCBICHM1_1
T2T-CHM13v2.06132,768,443 - 132,822,783 (-)NCBIT2T-CHM13v2.0
Med23
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391024,745,889 - 24,789,358 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1024,745,884 - 24,789,579 (+)EnsemblGRCm39 Ensembl
GRCm381024,869,986 - 24,913,529 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,869,986 - 24,913,681 (+)EnsemblGRCm38mm10GRCm38
MGSCv371024,589,792 - 24,633,335 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361024,559,463 - 24,602,876 (+)NCBIMGSCv36mm8
Celera1025,800,708 - 25,844,502 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1012.26NCBI
Med23
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8122,309,613 - 22,377,745 (-)NCBIGRCr8
mRatBN7.2120,490,315 - 20,558,461 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl120,490,315 - 20,537,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx120,266,984 - 20,314,129 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,266,973 - 26,314,118 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0120,466,878 - 20,514,023 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0121,539,765 - 21,587,675 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,539,765 - 21,586,910 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0123,019,607 - 23,067,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,013,168 - 21,060,313 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,013,763 - 21,065,733 (-)NCBI
Celera119,242,971 - 19,290,165 (-)NCBICelera
Cytogenetic Map1p12NCBI
Med23
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543612,249,995 - 12,293,813 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543612,249,995 - 12,293,812 (-)NCBIChiLan1.0ChiLan1.0
MED23
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.112195,638 - 240,741 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl12195,726 - 240,516 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha12333,600 - 378,570 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.012339,155 - 384,349 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl12339,124 - 418,391 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.112195,971 - 241,018 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.012266,817 - 311,872 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.012337,561 - 382,633 (+)NCBIUU_Cfam_GSD_1.0
Med23
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946119,962,645 - 120,004,052 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004937067849 - 41,298 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493706714 - 41,438 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MED23
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,959,934 - 32,001,581 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,959,934 - 32,001,591 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2135,469,173 - 35,507,325 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MED23
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11341,927,266 - 41,969,120 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1341,927,308 - 41,969,447 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604014,088,466 - 14,130,261 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Med23
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247535,751,779 - 5,799,413 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247535,751,782 - 5,799,305 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Sequence


Ensembl Acc Id: ENSPPAT00000020416   ⟹   ENSPPAP00000004433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6133,481,115 - 133,535,988 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000020436   ⟹   ENSPPAP00000004434
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6133,493,761 - 133,535,988 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000020458   ⟹   ENSPPAP00000004438
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6133,494,520 - 133,535,153 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000020459   ⟹   ENSPPAP00000004439
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl6133,510,309 - 133,535,153 (-)Ensembl
RefSeq Acc Id: XM_008953007   ⟹   XP_008951255
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25151,592,256 - 151,634,143 (-)NCBI
NHGRI_mPanPan16149,498,888 - 149,540,745 (-)NCBI
Mhudiblu_PPA_v06129,386,381 - 129,428,120 (-)NCBI
PanPan1.16133,493,587 - 133,535,337 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953008   ⟹   XP_008951256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v25151,592,256 - 151,634,143 (-)NCBI
NHGRI_mPanPan16149,498,888 - 149,540,825 (-)NCBI
Mhudiblu_PPA_v06129,386,301 - 129,428,046 (-)NCBI
PanPan1.16133,493,587 - 133,535,337 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008951255 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951256 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004433
  ENSPPAP00000004433.1
  ENSPPAP00000004434.1
  ENSPPAP00000004438
  ENSPPAP00000004438.1
  ENSPPAP00000004439.1
RefSeq Acc Id: XP_008951256   ⟸   XM_008953008
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZNS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951255   ⟸   XM_008953007
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZNS0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000004434   ⟸   ENSPPAT00000020436
Ensembl Acc Id: ENSPPAP00000004433   ⟸   ENSPPAT00000020416
Ensembl Acc Id: ENSPPAP00000004438   ⟸   ENSPPAT00000020458
Ensembl Acc Id: ENSPPAP00000004439   ⟸   ENSPPAT00000020459


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000018660 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000020416.1 UniProtKB/TrEMBL
  ENSPPAT00000020436.1 UniProtKB/TrEMBL
  ENSPPAT00000020458.1 UniProtKB/TrEMBL
  ENSPPAT00000020459.1 UniProtKB/TrEMBL
InterPro Mediator_Med23 UniProtKB/TrEMBL
NCBI Gene MED23 ENTREZGENE
PANTHER MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 UniProtKB/TrEMBL
  PTHR12691 UniProtKB/TrEMBL
Pfam Med23 UniProtKB/TrEMBL
UniProt A0A2R8ZHI1_PANPA UniProtKB/TrEMBL
  A0A2R8ZHI7_PANPA UniProtKB/TrEMBL
  A0A2R8ZNR6_PANPA UniProtKB/TrEMBL
  A0A2R8ZNS0 ENTREZGENE, UniProtKB/TrEMBL