CEBPA (CCAAT enhancer binding protein alpha) - Rat Genome Database

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Gene: CEBPA (CCAAT enhancer binding protein alpha) Pan paniscus
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Symbol: CEBPA
Name: CCAAT enhancer binding protein alpha
RGD ID: 11739234
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromatin DNA binding (ortholog); DNA binding (ortholog); INVOLVED IN acute-phase response (ortholog); animal organ regeneration (ortholog); brown fat cell differentiation (ortholog); PARTICIPATES IN forkhead class A signaling pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute promyelocytic leukemia (ortholog); Acute-Phase Reaction (ortholog); FOUND IN C/EBP complex (ortholog); CHOP-C/EBP complex (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CCAAT/enhancer binding protein alpha; CCAAT/enhancer-binding protein alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11938,969,065 - 38,971,031 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01930,223,567 - 30,226,204 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
animal organ regeneration  (ISO)
brown fat cell differentiation  (ISO)
cell differentiation  (ISO)
cell population proliferation  (ISO)
cellular response to lithium ion  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cholesterol metabolic process  (ISO)
embryonic placenta development  (ISO)
epithelial cell maturation  (ISO)
fat cell differentiation  (ISO)
glucose homeostasis  (ISO)
granulocyte differentiation  (ISO)
hematopoietic stem cell proliferation  (ISO)
inner ear development  (ISO)
interleukin-6-mediated signaling pathway  (ISO)
lipid homeostasis  (ISO)
liver development  (ISO)
lung development  (ISO)
macrophage differentiation  (ISO)
memory  (ISO)
mitochondrion organization  (ISO)
myeloid cell differentiation  (ISO)
negative regulation of cell cycle  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of hematopoietic stem cell proliferation  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
Notch signaling pathway  (ISO)
osteoblast development  (ISO)
positive regulation of DNA-templated transcription, initiation  (ISO)
positive regulation of fat cell differentiation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inflammatory response  (ISO)
positive regulation of macrophage activation  (ISO)
positive regulation of osteoblast differentiation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription by RNA polymerase III  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
regulation of cell population proliferation  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
regulation of transcription, DNA-templated  (IEA,ISO)
response to dexamethasone  (ISO)
response to nutrient  (ISO)
response to phenylpropanoid  (ISO)
response to vitamin B2  (ISO)
transcription by RNA polymerase I  (ISO)
urea cycle  (ISO)
white fat cell differentiation  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
CEBPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11938,969,065 - 38,971,031 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01930,223,567 - 30,226,204 (-)NCBIMhudiblu_PPA_v0panPan3
CEBPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381933,299,934 - 33,302,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1933,299,934 - 33,302,534 (-)EnsemblGRCh38hg38GRCh38
GRCh371933,790,840 - 33,793,440 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361938,482,776 - 38,485,160 (-)NCBINCBI36hg18NCBI36
Build 341938,482,775 - 38,485,160NCBI
Celera1930,484,405 - 30,486,995 (-)NCBI
Cytogenetic Map19q13.11NCBI
HuRef1930,291,676 - 30,294,205 (-)NCBIHuRef
CHM1_11933,791,795 - 33,794,385 (-)NCBICHM1_1
T2T-CHM13v2.01935,819,706 - 35,822,306 (-)NCBI
Cebpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,818,718 - 34,821,353 (+)NCBIGRCm39mm39
GRCm39 Ensembl734,818,718 - 34,821,353 (+)Ensembl
GRCm38735,119,293 - 35,121,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl735,119,293 - 35,121,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv37735,904,312 - 35,906,947 (+)NCBIGRCm37mm9NCBIm37
MGSCv36734,828,063 - 34,830,688 (+)NCBImm8
Celera730,255,122 - 30,257,756 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map721.02NCBI
Cebpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2187,759,631 - 87,762,303 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl187,759,433 - 87,762,412 (-)Ensembl
Rnor_6.0191,363,492 - 91,366,164 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl191,363,492 - 91,366,164 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0192,493,857 - 92,495,245 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4187,626,111 - 87,627,499 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1187,704,351 - 87,705,428 (+)NCBI
Celera182,110,797 - 82,113,472 (+)NCBICelera
Cytogenetic Map1q21NCBI
Cebpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554683,047,931 - 3,049,080 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554683,046,544 - 3,049,217 (-)NCBIChiLan1.0ChiLan1.0
CEBPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11118,846,252 - 118,851,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1118,249,214 - 118,251,848 (+)NCBI
ROS_Cfam_1.01119,446,691 - 119,449,313 (+)NCBI
UMICH_Zoey_3.11119,007,283 - 119,009,910 (+)NCBI
UNSW_CanFamBas_1.01118,633,880 - 118,636,501 (+)NCBI
UU_Cfam_GSD_1.01119,692,609 - 119,695,231 (+)NCBI
Cebpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093499,129,664 - 9,132,348 (-)NCBI
SpeTri2.0NW_0049365702,513,561 - 2,516,213 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CEBPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl643,083,203 - 43,085,836 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1643,083,200 - 43,085,884 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2638,632,195 - 38,634,910 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CEBPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1628,342,506 - 28,345,759 (-)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660736,065,215 - 6,067,832 (-)NCBIVero_WHO_p1.0
Cebpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247949,809,007 - 9,813,418 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003846126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_003846126   ⟹   XP_003846174
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11938,969,065 - 38,971,031 (-)NCBI
Mhudiblu_PPA_v01930,223,567 - 30,226,204 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003846174 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003846174   ⟸   XM_003846126
- Sequence:
Protein Domains
bZIP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000014349 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000003416 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000015703 UniProtKB/TrEMBL
InterPro bZIP UniProtKB/TrEMBL
NCBI Gene CEBPA ENTREZGENE
Pfam bZIP_2 UniProtKB/TrEMBL
PROSITE BZIP UniProtKB/TrEMBL
SMART BRLZ UniProtKB/TrEMBL
UniProt A0A2R8ZKZ7_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-27 CEBPA  CCAAT enhancer binding protein alpha    CCAAT/enhancer binding protein alpha  Symbol and/or name change 5135510 APPROVED