GTPBP4 (GTP binding protein 4) - Rat Genome Database

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Gene: GTPBP4 (GTP binding protein 4) Pan paniscus
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Symbol: GTPBP4
Name: GTP binding protein 4
RGD ID: 11737898
Description: ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); preribosome binding (inferred); INVOLVED IN maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (ortholog); regulation of cyclin-dependent protein serine/threonine kinase activity (ortholog); ASSOCIATED WITH end stage renal disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GTP-binding protein 4; nucleolar GTP-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2813,504,820 - 13,542,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11013,516,580 - 13,547,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0101,023,295 - 1,055,818 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1101,071,809 - 1,103,527 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl101,071,809 - 1,103,521 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GTPBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2813,504,820 - 13,542,455 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11013,516,580 - 13,547,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0101,023,295 - 1,055,818 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1101,071,809 - 1,103,527 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl101,071,809 - 1,103,521 (+)Ensemblpanpan1.1panPan2
GTPBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810988,434 - 1,019,932 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10988,434 - 1,019,932 (+)EnsemblGRCh38hg38GRCh38
GRCh37101,034,374 - 1,065,872 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36101,024,349 - 1,053,708 (+)NCBINCBI36Build 36hg18NCBI36
Build 34101,024,348 - 1,053,707NCBI
Celera10984,242 - 1,013,986 (+)NCBICelera
Cytogenetic Map10p15.3NCBI
HuRef10973,776 - 1,003,177 (+)NCBIHuRef
CHM1_1101,033,522 - 1,062,866 (+)NCBICHM1_1
T2T-CHM13v2.010985,662 - 1,017,099 (+)NCBIT2T-CHM13v2.0
Gtpbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39139,016,039 - 9,046,080 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl139,016,367 - 9,046,119 (-)EnsemblGRCm39 Ensembl
GRCm38138,972,070 - 8,996,116 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl138,966,331 - 8,996,083 (-)EnsemblGRCm38mm10GRCm38
MGSCv37138,971,710 - 8,995,258 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36138,971,710 - 8,995,258 (-)NCBIMGSCv36mm8
Celera138,914,114 - 8,937,545 (-)NCBICelera
Cytogenetic Map13A1NCBI
cM Map133.64NCBI
Gtpbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81765,997,472 - 66,019,530 (+)NCBIGRCr8
mRatBN7.21761,308,033 - 61,328,184 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1761,308,014 - 61,418,009 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX1,432,978 - 1,435,292 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X4,908,673 - 4,910,987 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X1,224,016 - 1,226,329 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01763,111,086 - 63,145,618 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1763,110,254 - 63,145,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01759,576,852 - 59,621,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01764,882,150 - 64,895,590 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01764,910,285 - 64,916,648 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41772,100,899 - 72,120,636 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11772,111,731 - 72,131,468 (+)NCBI
Celera1759,257,948 - 59,272,929 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Gtpbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554925,594 - 34,111 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554925,594 - 33,558 (-)NCBIChiLan1.0ChiLan1.0
GTPBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1233,936,629 - 33,955,947 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl233,936,637 - 34,024,769 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha230,973,045 - 30,991,292 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0234,322,186 - 34,341,038 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl234,322,193 - 34,340,957 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1231,405,444 - 31,424,272 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0232,245,151 - 32,263,987 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0232,992,243 - 33,011,090 (-)NCBIUU_Cfam_GSD_1.0
Gtpbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934436,936,100 - 36,961,994 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648413,101,328 - 13,127,211 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTPBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1068,547,319 - 68,568,713 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11068,547,316 - 68,566,040 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21075,547,092 - 75,575,126 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTPBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19953,062 - 981,213 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9952,663 - 981,353 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660516,007,162 - 6,035,503 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtpbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247759,933,339 - 9,965,761 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247759,933,500 - 9,965,816 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000061614   ⟹   ENSPPAP00000038708
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl101,071,809 - 1,103,521 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000061628   ⟹   ENSPPAP00000038722
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl101,071,874 - 1,100,819 (+)Ensembl
RefSeq Acc Id: XM_003827759   ⟹   XP_003827807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2813,504,820 - 13,542,455 (+)NCBI
NHGRI_mPanPan11013,516,580 - 13,547,712 (+)NCBI
Mhudiblu_PPA_v0101,023,295 - 1,055,818 (+)NCBI
PanPan1.1101,071,809 - 1,103,527 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008953089   ⟹   XP_008951337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2813,511,261 - 13,542,455 (+)NCBI
NHGRI_mPanPan11013,516,607 - 13,547,712 (+)NCBI
Mhudiblu_PPA_v0101,023,343 - 1,055,818 (+)NCBI
PanPan1.1101,071,822 - 1,103,527 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003827807 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951337 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038708.1
  ENSPPAP00000038722.1
RefSeq Acc Id: XP_003827807   ⟸   XM_003827759
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CKQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008951337   ⟸   XM_008953089
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CKQ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000038708   ⟸   ENSPPAT00000061614
Ensembl Acc Id: ENSPPAP00000038722   ⟸   ENSPPAT00000061628
Protein Domains
OBG-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042066 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061614.1 UniProtKB/TrEMBL
  ENSPPAT00000061628.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.1190 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro G_OBG UniProtKB/TrEMBL
  GTP-bd UniProtKB/TrEMBL
  NOG1 UniProtKB/TrEMBL
  NOG1_N UniProtKB/TrEMBL
  NOG1_Rossman_fold_dom UniProtKB/TrEMBL
  NOG_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
KEGG Report pps:100974616 UniProtKB/TrEMBL
NCBI Gene GTPBP4 ENTREZGENE
PANTHER GTP-BINDING PROTEIN 4 UniProtKB/TrEMBL
  NUCLEOLAR GTP-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam NOG1 UniProtKB/TrEMBL
  NOG1_N UniProtKB/TrEMBL
  NOGCT UniProtKB/TrEMBL
PIRSF NOG1 UniProtKB/TrEMBL
PRINTS GTP1OBG UniProtKB/TrEMBL
PROSITE G_OBG UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9CCI7_PANPA UniProtKB/TrEMBL
  A0A2R9CKQ0 ENTREZGENE, UniProtKB/TrEMBL