LIMS2 (LIM zinc finger domain containing 2) - Rat Genome Database

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Gene: LIMS2 (LIM zinc finger domain containing 2) Pan paniscus
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Symbol: LIMS2
Name: LIM zinc finger domain containing 2
RGD ID: 11736305
Description: ENCODES a protein that exhibits metal ion binding (inferred); INVOLVED IN cell-cell adhesion (ortholog); cell-cell junction organization (ortholog); cholangiocyte proliferation (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH autosomal dominant thrombophilia due to protein C deficiency (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2W (ortholog); centronuclear myopathy 2 (ortholog); FOUND IN anchoring junction (inferred); cell-cell junction (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LIM and senescent cell antigen-like-containing domain protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21347,962,453 - 48,005,844 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B47,977,422 - 48,020,823 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B32,594,330 - 32,637,697 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B128,304,799 - 128,347,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,304,799 - 128,347,951 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LIMS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21347,962,453 - 48,005,844 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B47,977,422 - 48,020,823 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B32,594,330 - 32,637,697 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B128,304,799 - 128,347,951 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B128,304,799 - 128,347,951 (-)Ensemblpanpan1.1panPan2
LIMS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382127,638,426 - 127,681,786 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2127,638,381 - 127,681,786 (-)EnsemblGRCh38hg38GRCh38
GRCh372128,396,001 - 128,439,360 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362128,112,471 - 128,138,590 (-)NCBINCBI36Build 36hg18NCBI36
Build 342128,112,232 - 128,138,343NCBI
Celera2121,706,938 - 121,750,307 (-)NCBICelera
Cytogenetic Map2q14.3NCBI
HuRef2120,702,371 - 120,745,600 (-)NCBIHuRef
CHM1_12128,400,424 - 128,443,742 (-)NCBICHM1_1
T2T-CHM13v2.02128,073,680 - 128,117,027 (-)NCBIT2T-CHM13v2.0
Lims2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391832,055,346 - 32,091,673 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1832,055,343 - 32,091,672 (+)EnsemblGRCm39 Ensembl
GRCm381831,922,293 - 31,958,620 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1831,922,290 - 31,958,619 (+)EnsemblGRCm38mm10GRCm38
MGSCv371832,091,161 - 32,118,273 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361832,074,517 - 32,101,629 (+)NCBIMGSCv36mm8
Celera1832,422,000 - 32,448,987 (+)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1817.89NCBI
Lims2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,828,164 - 23,866,363 (+)NCBIGRCr8
mRatBN7.21823,553,937 - 23,592,137 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,553,937 - 23,592,137 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,682,035 - 23,720,226 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01824,431,078 - 24,469,221 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,777,003 - 23,815,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,707,951 - 24,746,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,708,115 - 24,746,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01824,422,274 - 24,460,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41824,347,374 - 24,386,082 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11824,374,019 - 24,412,728 (+)NCBI
Celera1823,306,381 - 23,344,707 (+)NCBICelera
Cytogenetic Map18p12NCBI
Lims2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554592,864,580 - 2,914,263 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554592,874,282 - 2,913,956 (+)NCBIChiLan1.0ChiLan1.0
LIMS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11922,932,251 - 22,978,437 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1922,931,779 - 22,982,765 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1923,179,486 - 23,225,586 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01924,258,143 - 24,304,404 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1924,263,562 - 24,304,401 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11922,962,031 - 23,008,263 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01923,156,801 - 23,202,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01924,288,646 - 24,334,679 (+)NCBIUU_Cfam_GSD_1.0
Lims2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530397,952,575 - 97,989,447 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646943,634,074 - 43,665,175 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646943,628,280 - 43,665,145 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIMS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1559,672,540 - 59,709,379 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11559,672,508 - 59,709,380 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21566,435,456 - 66,458,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LIMS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1102,540,383 - 2,578,117 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl102,543,091 - 2,579,332 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606120,181,687 - 20,218,054 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lims2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473214,102,543 - 14,144,722 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473214,102,543 - 14,144,479 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003828252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008953606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008953614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008953615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034954226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055108567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057301411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063595190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063595191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063595192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000051418   ⟹   ENSPPAP00000028571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,304,799 - 128,347,951 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051423   ⟹   ENSPPAP00000028576
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,304,799 - 128,340,299 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051425   ⟹   ENSPPAP00000028578
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,304,799 - 128,330,908 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051432   ⟹   ENSPPAP00000028584
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,304,799 - 128,324,832 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051438   ⟹   ENSPPAP00000028591
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,305,658 - 128,324,193 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051441   ⟹   ENSPPAP00000028593
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B128,305,658 - 128,312,352 (-)Ensembl
RefSeq Acc Id: XM_008953606   ⟹   XP_008951854
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,977,605 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B47,994,344 - 48,020,823 (+)NCBI
Mhudiblu_PPA_v02B32,611,490 - 32,637,697 (+)NCBI
PanPan1.12B128,304,799 - 128,330,908 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034954220   ⟹   XP_034810111
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,968,163 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B47,983,400 - 48,020,823 (+)NCBI
Mhudiblu_PPA_v02B32,600,318 - 32,637,692 (+)NCBI
RefSeq Acc Id: XM_034954222   ⟹   XP_034810113
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,968,399 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B47,983,402 - 48,020,823 (+)NCBI
Mhudiblu_PPA_v02B32,600,819 - 32,637,692 (+)NCBI
RefSeq Acc Id: XM_034954223   ⟹   XP_034810114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,968,397 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B47,983,400 - 48,020,823 (+)NCBI
Mhudiblu_PPA_v02B32,600,304 - 32,637,692 (+)NCBI
RefSeq Acc Id: XM_034954226   ⟹   XP_034810117
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,962,453 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B47,977,422 - 48,020,823 (+)NCBI
Mhudiblu_PPA_v02B32,594,633 - 32,637,692 (+)NCBI
RefSeq Acc Id: XM_055108567   ⟹   XP_054964542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,993,537 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B48,008,491 - 48,020,823 (+)NCBI
RefSeq Acc Id: XM_057301411   ⟹   XP_057157394
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,996,259 - 48,005,844 (+)NCBI
NHGRI_mPanPan12B48,011,235 - 48,020,823 (+)NCBI
RefSeq Acc Id: XM_063595190   ⟹   XP_063451260
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,968,410 - 48,005,844 (+)NCBI
RefSeq Acc Id: XM_063595191   ⟹   XP_063451261
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,989,511 - 48,005,844 (+)NCBI
RefSeq Acc Id: XM_063595192   ⟹   XP_063451262
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21347,968,394 - 48,005,844 (+)NCBI
RefSeq Acc Id: XP_008951854   ⟸   XM_008953606
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BH15 (UniProtKB/TrEMBL),   A0A2R9BPK6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034810117   ⟸   XM_034954226
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BPK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810114   ⟸   XM_034954223
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BH26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810111   ⟸   XM_034954220
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BPK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034810113   ⟸   XM_034954222
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BPK6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028578   ⟸   ENSPPAT00000051425
RefSeq Acc Id: ENSPPAP00000028576   ⟸   ENSPPAT00000051423
RefSeq Acc Id: ENSPPAP00000028571   ⟸   ENSPPAT00000051418
RefSeq Acc Id: ENSPPAP00000028584   ⟸   ENSPPAT00000051432
RefSeq Acc Id: ENSPPAP00000028593   ⟸   ENSPPAT00000051441
RefSeq Acc Id: ENSPPAP00000028591   ⟸   ENSPPAT00000051438
RefSeq Acc Id: XP_054964542   ⟸   XM_055108567
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BH26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057157394   ⟸   XM_057301411
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BH26 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063451262   ⟸   XM_063595192
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063451260   ⟸   XM_063595190
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063451261   ⟸   XM_063595191
- Peptide Label: isoform X7
Protein Domains
LIM zinc-binding


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037291 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051418.1 UniProtKB/TrEMBL
  ENSPPAT00000051423.1 UniProtKB/TrEMBL
  ENSPPAT00000051425.1 UniProtKB/TrEMBL
  ENSPPAT00000051432.1 UniProtKB/TrEMBL
  ENSPPAT00000051438.1 UniProtKB/TrEMBL
  ENSPPAT00000051441.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/TrEMBL
InterPro LIMS1/2-like_LIM1 UniProtKB/TrEMBL
  PINCH-1/2-like UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
NCBI Gene LIMS2 ENTREZGENE
PANTHER LIM AND SENESCENT CELL ANTIGEN-LIKE-CONTAINING DOMAIN PROTEIN 2 UniProtKB/TrEMBL
  PTHR24210 UniProtKB/TrEMBL
Pfam LIM UniProtKB/TrEMBL
PIRSF PINCH UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
UniProt A0A2R9BG17_PANPA UniProtKB/TrEMBL
  A0A2R9BH15 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BH26 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BPK6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BPL1_PANPA UniProtKB/TrEMBL
  A0A2R9BPM2_PANPA UniProtKB/TrEMBL