SH3RF2 (SH3 domain containing ring finger 2) - Rat Genome Database

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Gene: SH3RF2 (SH3 domain containing ring finger 2) Pan paniscus
Analyze
Symbol: SH3RF2
Name: SH3 domain containing ring finger 2
RGD ID: 11736150
Description: ENCODES a protein that exhibits metal ion binding (inferred); phosphatase binding (inferred); protein phosphatase 1 binding (inferred); INVOLVED IN negative regulation of JNK cascade (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase SH3RF2; putative E3 ubiquitin-protein ligase SH3RF2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24141,189,983 - 141,335,567 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15139,329,533 - 139,471,859 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05141,386,060 - 141,530,993 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15147,401,188 - 147,545,703 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5147,401,188 - 147,545,703 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SH3RF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24141,189,983 - 141,335,567 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15139,329,533 - 139,471,859 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05141,386,060 - 141,530,993 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15147,401,188 - 147,545,703 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5147,401,188 - 147,545,703 (+)Ensemblpanpan1.1panPan2
SH3RF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385145,936,578 - 146,081,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5145,936,578 - 146,081,791 (+)EnsemblGRCh38hg38GRCh38
GRCh375145,316,141 - 145,442,855 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365145,296,335 - 145,423,048 (+)NCBINCBI36Build 36hg18NCBI36
Build 345145,296,334 - 145,423,047NCBI
Celera5141,396,292 - 141,522,973 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5140,462,976 - 140,589,659 (+)NCBIHuRef
CHM1_15144,748,936 - 144,875,627 (+)NCBICHM1_1
T2T-CHM13v2.05146,470,962 - 146,616,058 (+)NCBIT2T-CHM13v2.0
Sh3rf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391842,185,531 - 42,291,760 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1842,186,732 - 42,292,025 (+)EnsemblGRCm39 Ensembl
GRCm381842,052,502 - 42,158,695 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1842,053,667 - 42,158,960 (+)EnsemblGRCm38mm10GRCm38
MGSCv371842,213,364 - 42,318,349 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361842,179,683 - 42,284,424 (+)NCBIMGSCv36mm8
Celera1843,415,332 - 43,520,074 (+)NCBICelera
Cytogenetic Map18B3NCBI
cM Map1822.21NCBI
Sh3rf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81834,296,753 - 34,397,880 (+)NCBIGRCr8
mRatBN7.21834,045,715 - 34,148,342 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1834,046,879 - 34,146,856 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1834,151,092 - 34,251,070 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01834,869,409 - 34,969,391 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01834,246,335 - 34,346,293 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01836,371,041 - 36,471,020 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1836,371,041 - 36,471,015 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01836,038,469 - 36,138,307 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41835,242,898 - 35,344,485 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11835,278,198 - 35,379,745 (+)NCBI
Celera1833,643,909 - 33,743,873 (+)NCBICelera
Cytogenetic Map18p11NCBI
Sh3rf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554158,042,380 - 8,147,564 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554158,024,984 - 8,148,970 (-)NCBIChiLan1.0ChiLan1.0
SH3RF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1240,380,313 - 40,514,211 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl240,380,218 - 40,510,853 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha237,425,282 - 37,559,026 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0240,843,992 - 40,977,969 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl240,843,847 - 40,977,015 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1237,910,939 - 38,044,681 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0238,727,553 - 38,861,209 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0239,552,296 - 39,686,259 (+)NCBIUU_Cfam_GSD_1.0
Sh3rf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213147,025,186 - 147,157,157 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365048,599,157 - 8,731,118 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365048,602,116 - 8,731,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3RF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2147,290,579 - 147,413,143 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12147,290,322 - 147,413,151 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22153,801,407 - 153,932,618 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SH3RF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12348,512,549 - 48,655,652 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2348,512,548 - 48,658,365 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603429,132,374 - 29,278,260 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3rf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247745,327,570 - 5,555,645 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247745,319,329 - 5,554,823 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000062318   ⟹   ENSPPAP00000039407
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5147,401,188 - 147,545,703 (+)Ensembl
RefSeq Acc Id: XM_008954496   ⟹   XP_008952744
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,190,010 - 141,335,566 (+)NCBI
NHGRI_mPanPan15139,329,560 - 139,471,859 (+)NCBI
Mhudiblu_PPA_v05141,386,060 - 141,530,993 (+)NCBI
PanPan1.15147,401,188 - 147,545,703 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034960717   ⟹   XP_034816608
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,189,992 - 141,316,097 (+)NCBI
NHGRI_mPanPan15139,329,542 - 139,455,642 (+)NCBI
Mhudiblu_PPA_v05141,386,066 - 141,512,142 (+)NCBI
RefSeq Acc Id: XM_034960719   ⟹   XP_034816610
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,189,992 - 141,316,097 (+)NCBI
NHGRI_mPanPan15139,329,542 - 139,455,642 (+)NCBI
Mhudiblu_PPA_v05141,386,066 - 141,512,142 (+)NCBI
RefSeq Acc Id: XM_055112745   ⟹   XP_054968720
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,189,983 - 141,316,097 (+)NCBI
NHGRI_mPanPan15139,329,533 - 139,455,642 (+)NCBI
RefSeq Acc Id: XM_063604663   ⟹   XP_063460733
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,189,992 - 141,335,567 (+)NCBI
RefSeq Acc Id: XM_063604664   ⟹   XP_063460734
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24141,189,992 - 141,316,097 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008952744   ⟸   XM_008954496
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CMR3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034816608   ⟸   XM_034960717
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CMR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034816610   ⟸   XM_034960719
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CMR3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000039407   ⟸   ENSPPAT00000062318
RefSeq Acc Id: XP_054968720   ⟸   XM_055112745
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063460733   ⟸   XM_063604663
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063460734   ⟸   XM_063604664
- Peptide Label: isoform X3
Protein Domains
RING-type   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042408 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062318.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  SH3RF2_RING-HC_Zfn UniProtKB/TrEMBL
  SH3RF2_SH3_1 UniProtKB/TrEMBL
  SH3RF2_SH3_2 UniProtKB/TrEMBL
  SH3RF2_SH3_3 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report pps:100995837 UniProtKB/TrEMBL
NCBI Gene SH3RF2 ENTREZGENE
PANTHER PTHR14167:SF60 UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam SH3_1 UniProtKB/TrEMBL
  SH3_2 UniProtKB/TrEMBL
  SH3_9 UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PRINTS SH3DOMAIN UniProtKB/TrEMBL
PROSITE SH3 UniProtKB/TrEMBL
  ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt A0A2R9CMR3 ENTREZGENE, UniProtKB/TrEMBL