RFLNB (refilin B) - Rat Genome Database

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Gene: RFLNB (refilin B) Pan paniscus
Analyze
Symbol: RFLNB
Name: refilin B
RGD ID: 11736086
Description: ENCODES a protein that exhibits filamin binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament bundle organization (ortholog); epithelial to mesenchymal transition (ortholog); ASSOCIATED WITH cholestasis (ortholog); FOUND IN actin cytoskeleton (inferred); actin filament bundle (inferred); cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: filamin-interacting protein FAM101B; refilin-B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,012,363 - 8,023,112 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,558,897 - 9,569,421 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017359,016 - 367,464 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117375,874 - 384,872 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17375,885 - 381,580 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
cholestasis  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RFLNB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2198,012,363 - 8,023,112 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1179,558,897 - 9,569,421 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v017359,016 - 367,464 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.117375,874 - 384,872 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl17375,885 - 381,580 (-)Ensemblpanpan1.1panPan2
RFLNB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3817439,978 - 445,940 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl17439,978 - 445,939 (-)EnsemblGRCh38hg38GRCh38
GRCh3717289,769 - 295,731 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3617289,997 - 295,959 (-)NCBINCBI36Build 36hg18NCBI36
Celera17390,834 - 394,350 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef17301,396 - 307,358 (-)NCBIHuRef
CHM1_117298,551 - 304,511 (-)NCBICHM1_1
T2T-CHM13v2.017361,879 - 374,190 (-)NCBIT2T-CHM13v2.0
Rflnb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391175,910,020 - 75,918,608 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1175,910,020 - 75,918,608 (-)EnsemblGRCm39 Ensembl
GRCm381176,019,194 - 76,027,782 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1176,019,194 - 76,027,782 (-)EnsemblGRCm38mm10GRCm38
MGSCv371175,832,696 - 75,841,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361175,835,392 - 75,844,219 (-)NCBIMGSCv36mm8
Celera1183,528,300 - 83,536,915 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.92NCBI
Rflnb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81061,391,947 - 61,398,224 (-)NCBIGRCr8
mRatBN7.21060,893,693 - 60,899,970 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1060,893,713 - 60,899,976 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1065,535,866 - 65,542,094 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01065,041,316 - 65,047,544 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01060,511,848 - 60,518,117 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01064,196,103 - 64,202,380 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1064,196,127 - 64,202,380 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01063,810,534 - 63,816,811 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41063,384,402 - 63,390,679 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11063,398,048 - 63,404,302 (-)NCBI
Celera1059,909,698 - 59,915,491 (-)NCBICelera
Cytogenetic Map10q24NCBI
Rflnb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554812,102,586 - 2,107,967 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554812,102,576 - 2,107,947 (-)NCBIChiLan1.0ChiLan1.0
RFLNB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1945,232,910 - 45,239,569 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl945,232,975 - 45,239,130 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha944,382,987 - 44,391,993 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0946,051,227 - 46,060,240 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl946,051,277 - 46,057,442 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1944,829,900 - 44,838,890 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0945,123,087 - 45,132,085 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0945,202,100 - 45,211,135 (+)NCBIUU_Cfam_GSD_1.0
Rflnb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560244,348,625 - 44,357,796 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365387,226,570 - 7,233,185 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365387,226,570 - 7,233,203 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RFLNB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1247,307,637 - 47,314,589 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11247,307,657 - 47,316,652 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21249,516,707 - 49,525,696 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RFLNB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.116269,395 - 278,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl16271,418 - 278,115 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605921,812,071 - 21,821,657 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rflnb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247863,793,302 - 3,801,630 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247863,793,266 - 3,801,894 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034941195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000059970   ⟹   ENSPPAP00000037074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl17375,885 - 381,580 (-)Ensembl
RefSeq Acc Id: XM_034941195   ⟹   XP_034797086
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2198,012,363 - 8,023,112 (-)NCBI
NHGRI_mPanPan1179,558,897 - 9,569,421 (-)NCBI
Mhudiblu_PPA_v017359,016 - 367,464 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034797086 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037074.1
Reference Protein Sequences
RefSeq Acc Id: XP_034797086   ⟸   XM_034941195
RefSeq Acc Id: ENSPPAP00000037074   ⟸   ENSPPAT00000059970


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041290 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059970.1 UniProtKB/TrEMBL
InterPro Refilin UniProtKB/TrEMBL
NCBI Gene RFLNB ENTREZGENE
PANTHER PTHR31848 UniProtKB/TrEMBL
  REFILIN-B UniProtKB/TrEMBL
Pfam FAM101 UniProtKB/TrEMBL
UniProt A0A2R9C5H2_PANPA UniProtKB/TrEMBL