GRHL2 (grainyhead like transcription factor 2) - Rat Genome Database

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Gene: GRHL2 (grainyhead like transcription factor 2) Pan paniscus
Analyze
Symbol: GRHL2
Name: grainyhead like transcription factor 2
RGD ID: 11732788
Description: ENCODES a protein that exhibits chromatin binding (inferred); chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN anterior neural tube closure (ortholog); brain development (ortholog); camera-type eye development (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 28 (ortholog); Cohen syndrome (ortholog); corneal dystrophy (ortholog); FOUND IN cell-cell junction (inferred); nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: grainyhead-like 2; grainyhead-like protein 2 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27118,838,709 - 119,023,205 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1894,375,363 - 94,559,131 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0898,129,147 - 98,308,120 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18100,295,531 - 100,471,830 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8100,308,575 - 100,471,830 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GRHL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27118,838,709 - 119,023,205 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1894,375,363 - 94,559,131 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0898,129,147 - 98,308,120 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18100,295,531 - 100,471,830 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8100,308,575 - 100,471,830 (+)Ensemblpanpan1.1panPan2
GRHL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388101,492,439 - 101,681,200 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8101,492,439 - 101,669,726 (+)EnsemblGRCh38hg38GRCh38
GRCh378102,504,667 - 102,681,954 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368102,574,162 - 102,750,995 (+)NCBINCBI36Build 36hg18NCBI36
Build 348102,574,161 - 102,750,995NCBI
Celera898,689,599 - 98,866,864 (+)NCBICelera
Cytogenetic Map8q22.3NCBI
HuRef897,702,727 - 97,879,982 (+)NCBIHuRef
CHM1_18102,544,909 - 102,722,208 (+)NCBICHM1_1
T2T-CHM13v2.08102,618,002 - 102,807,085 (+)NCBIT2T-CHM13v2.0
Grhl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391537,233,065 - 37,363,813 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1537,233,280 - 37,363,813 (+)EnsemblGRCm39 Ensembl
GRCm381537,232,821 - 37,363,569 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1537,233,036 - 37,363,569 (+)EnsemblGRCm38mm10GRCm38
MGSCv371537,162,791 - 37,293,324 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361537,177,836 - 37,308,152 (+)NCBIMGSCv36mm8
Celera1537,856,086 - 37,983,260 (+)NCBICelera
Cytogenetic Map15B3.1NCBI
cM Map1514.84NCBI
Grhl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8770,280,360 - 70,415,277 (+)NCBIGRCr8
mRatBN7.2768,400,287 - 68,530,269 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl768,400,477 - 68,530,258 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx770,281,213 - 70,410,713 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0772,483,713 - 72,613,205 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0772,351,732 - 72,481,228 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0776,058,623 - 76,197,360 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl776,059,386 - 76,197,856 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0776,188,138 - 76,317,845 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4772,742,859 - 72,872,351 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera765,469,270 - 65,597,175 (+)NCBICelera
Cytogenetic Map7q22NCBI
Grhl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541726,401,363 - 26,533,297 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541726,401,337 - 26,533,297 (+)NCBIChiLan1.0ChiLan1.0
GRHL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1133,204,898 - 3,362,533 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl133,204,925 - 3,362,096 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha133,204,498 - 3,362,392 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0133,362,118 - 3,520,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl133,362,467 - 3,520,176 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1133,205,577 - 3,363,466 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0133,318,462 - 3,476,089 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0133,335,250 - 3,493,208 (+)NCBIUU_Cfam_GSD_1.0
Grhl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530334,430,577 - 34,577,590 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647041,859,035 - 42,002,844 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647041,856,683 - 41,961,666 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRHL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl435,371,136 - 35,564,919 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1435,368,788 - 35,565,394 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2438,263,513 - 38,412,524 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRHL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1896,340,459 - 96,526,366 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl896,342,189 - 96,526,363 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603944,151,564 - 44,338,050 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grhl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476318,784,187 - 18,916,358 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476318,784,815 - 18,916,358 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000063085   ⟹   ENSPPAP00000040171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8100,308,575 - 100,471,830 (+)Ensembl
RefSeq Acc Id: XM_008975192   ⟹   XP_008973440
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27118,838,709 - 119,023,205 (+)NCBI
NHGRI_mPanPan1894,375,363 - 94,559,131 (+)NCBI
Mhudiblu_PPA_v0898,129,148 - 98,308,120 (+)NCBI
PanPan1.18100,295,531 - 100,471,695 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055116805   ⟹   XP_054972780
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27118,838,709 - 119,023,205 (+)NCBI
NHGRI_mPanPan1894,375,363 - 94,559,131 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008973440 (Get FASTA)   NCBI Sequence Viewer  
  XP_054972780 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040171.1
Reference Protein Sequences
RefSeq Acc Id: XP_008973440   ⟸   XM_008975192
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CE02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000040171   ⟸   ENSPPAT00000063085
RefSeq Acc Id: XP_054972780   ⟸   XM_055116805
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CE02 (UniProtKB/TrEMBL)
Protein Domains
Grh/CP2 DB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042743 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063085.1 UniProtKB/TrEMBL
InterPro CP2 UniProtKB/TrEMBL
  TF_CP2-like UniProtKB/TrEMBL
NCBI Gene GRHL2 ENTREZGENE
PANTHER GRAINYHEAD-LIKE PROTEIN 2 HOMOLOG UniProtKB/TrEMBL
  TRANSCRIPTION FACTOR CP2 UniProtKB/TrEMBL
Pfam CP2 UniProtKB/TrEMBL
PROSITE GRH_CP2_DB UniProtKB/TrEMBL
UniProt A0A2R9CE02 ENTREZGENE, UniProtKB/TrEMBL