RIMS4 (regulating synaptic membrane exocytosis 4) - Rat Genome Database

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Gene: RIMS4 (regulating synaptic membrane exocytosis 4) Pan paniscus
Analyze
Symbol: RIMS4
Name: regulating synaptic membrane exocytosis 4
RGD ID: 11732074
Description: ENCODES a protein that exhibits small GTPase binding (inferred); transmembrane transporter binding (inferred); INVOLVED IN regulation of membrane potential (ortholog); regulation of synapse organization (ortholog); regulation of synaptic vesicle exocytosis (ortholog); ASSOCIATED WITH focal epilepsy (ortholog); genetic disease (ortholog); T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulating synaptic membrane exocytosis protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,484,715 - 50,543,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,477,818 - 50,536,692 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,082,200 - 41,141,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,176,426 - 42,266,587 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,180,764 - 42,234,847 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RIMS4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,484,715 - 50,543,589 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,477,818 - 50,536,692 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,082,200 - 41,141,119 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,176,426 - 42,266,587 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,180,764 - 42,234,847 (-)Ensemblpanpan1.1panPan2
RIMS4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382044,751,808 - 44,810,546 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2044,751,808 - 44,810,546 (-)EnsemblGRCh38hg38GRCh38
GRCh372043,380,449 - 43,439,187 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362042,813,863 - 42,872,326 (-)NCBINCBI36Build 36hg18NCBI36
Build 342042,813,862 - 42,872,326NCBI
Celera2040,089,112 - 40,147,575 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2040,121,981 - 40,180,831 (-)NCBIHuRef
CHM1_12043,283,483 - 43,342,017 (-)NCBICHM1_1
T2T-CHM13v2.02046,487,544 - 46,546,418 (-)NCBIT2T-CHM13v2.0
Rims4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,701,676 - 163,760,893 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2163,701,671 - 163,760,603 (-)EnsemblGRCm39 Ensembl
GRCm382163,859,756 - 163,918,973 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2163,859,751 - 163,918,683 (-)EnsemblGRCm38mm10GRCm38
MGSCv372163,689,617 - 163,744,419 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362163,555,322 - 163,610,124 (-)NCBIMGSCv36mm8
Celera2169,800,550 - 169,854,461 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.52NCBI
Rims4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,940,404 - 173,004,490 (-)NCBIGRCr8
mRatBN7.23152,520,982 - 152,585,070 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3152,524,095 - 152,584,780 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3156,332,581 - 156,392,228 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03164,831,527 - 164,891,168 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03162,575,762 - 162,635,427 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03160,237,659 - 160,301,792 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3160,241,619 - 160,301,552 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03166,431,305 - 166,490,895 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,782,944 - 154,843,492 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13154,688,979 - 154,749,528 (-)NCBI
Celera3151,175,573 - 151,235,122 (-)NCBICelera
Cytogenetic Map3q42NCBI
Rims4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544512,542,818 - 12,604,355 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544512,542,824 - 12,604,355 (+)NCBIChiLan1.0ChiLan1.0
RIMS4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,199,068 - 32,256,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,203,410 - 32,256,480 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2431,839,817 - 31,928,051 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02432,905,312 - 32,993,662 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2432,907,289 - 32,968,231 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12432,166,872 - 32,254,873 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02432,281,598 - 32,369,791 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02432,823,164 - 32,911,484 (-)NCBIUU_Cfam_GSD_1.0
Rims4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640192,469,376 - 192,523,550 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,923,013 - 7,973,299 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,923,019 - 7,977,193 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIMS4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,167,305 - 47,235,386 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,167,302 - 47,235,237 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21752,620,971 - 52,627,488 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIMS4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1219,001,516 - 19,058,797 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl219,001,617 - 19,058,863 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605067,669,745 - 67,727,184 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rims4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247909,658,850 - 9,721,084 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247909,654,266 - 9,720,522 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044166   ⟹   ENSPPAP00000021364
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,180,764 - 42,234,847 (-)Ensembl
RefSeq Acc Id: XM_034947323   ⟹   XP_034803214
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,484,715 - 50,543,589 (-)NCBI
NHGRI_mPanPan12050,477,818 - 50,536,692 (-)NCBI
Mhudiblu_PPA_v02041,082,200 - 41,141,119 (-)NCBI
RefSeq Acc Id: XM_034947324   ⟹   XP_034803215
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,484,715 - 50,543,589 (-)NCBI
NHGRI_mPanPan12050,477,818 - 50,536,692 (-)NCBI
Mhudiblu_PPA_v02041,082,200 - 41,141,119 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034803214 (Get FASTA)   NCBI Sequence Viewer  
  XP_034803215 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021364.1
Reference Protein Sequences
RefSeq Acc Id: XP_034803215   ⟸   XM_034947324
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B1R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034803214   ⟸   XM_034947323
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B1R5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000021364   ⟸   ENSPPAT00000044166
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033892 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044166.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Rim-like UniProtKB/TrEMBL
NCBI Gene RIMS4 ENTREZGENE
PANTHER PTHR12157 UniProtKB/TrEMBL
  REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN 3 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A2R9B1R5 ENTREZGENE, UniProtKB/TrEMBL