NUDT14 (nudix hydrolase 14) - Rat Genome Database

Name: NUDT14
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: NUDT14 (nudix hydrolase 14) Pan paniscus

Analyze

Symbol:

NUDT14

Name:

nudix hydrolase 14

RGD ID:

11730918

Description:

ENCODES a protein that exhibits ADP-ribose diphosphatase activity (inferred); ADP-sugar diphosphatase activity (inferred); bis(5'-adenosyl)-pentaphosphatase activity (inferred); INVOLVED IN nucleoside phosphate metabolic process (inferred); ribose phosphate metabolic process (inferred); ASSOCIATED WITH Charcot-Marie-Tooth disease axonal type 2O (ortholog); focal segmental glomerulosclerosis 5 (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

uridine diphosphate glucose pyrophosphatase; uridine diphosphate glucose pyrophosphatase NUDT14

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NUDT14 (nudix hydrolase 14)	NCBI	Ortholog
Mus musculus (house mouse):	Nudt14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nudt14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nudt14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NUDT14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nudt14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NUDT14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103229796 (uridine diphosphate glucose pyrophosphatase NUDT14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nudt14 (nudix hydrolase 14)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	106,352,997 - 106,361,331 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	105,569,499 - 105,577,835 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	85,816,561 - 85,824,887 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	105,600,783 - 105,608,697 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	105,600,783 - 105,605,538 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease axonal type 2O (ISO)

focal segmental glomerulosclerosis 5 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

nucleoside phosphate metabolic process (IEA)

ribose phosphate metabolic process (IEA)

Cellular Component

cytosol (IEA)

Molecular Function

ADP-ribose diphosphatase activity (IEA)

ADP-sugar diphosphatase activity (IEA)

bis(5'-adenosyl)-pentaphosphatase activity (IEA)

guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (IEA)

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (IEA)

identical protein binding (IEA)

metal ion binding (IEA)

protein binding (ISO)

UDP-sugar diphosphatase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

NUDT14
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	106,352,997 - 106,361,331 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	105,569,499 - 105,577,835 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	85,816,561 - 85,824,887 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	105,600,783 - 105,608,697 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	105,600,783 - 105,605,538 (-)	Ensembl	panpan1.1		panPan2

NUDT14
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	105,172,939 - 105,181,312 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	105,172,938 - 105,181,323 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	105,639,276 - 105,647,649 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	104,710,321 - 104,718,685 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	104,710,321 - 104,718,685	NCBI
Celera	14	85,692,507 - 85,700,860 (-)	NCBI		Celera
Cytogenetic Map	14	q32.33	NCBI
HuRef	14	85,831,085 - 85,839,440 (-)	NCBI		HuRef
CHM1_1	14	105,577,035 - 105,585,421 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	99,414,864 - 99,423,206 (-)	NCBI		T2T-CHM13v2.0

Nudt14
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	112,897,911 - 112,905,762 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	112,897,911 - 112,905,744 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	112,934,291 - 112,942,142 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	112,934,291 - 112,942,124 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	114,172,944 - 114,180,329 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	113,382,541 - 113,389,926 (-)	NCBI		MGSCv36	mm8
Celera	12	114,145,321 - 114,152,146 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	61.42	NCBI

Nudt14
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	137,831,382 - 137,838,370 (-)	NCBI		GRCr8
mRatBN7.2	6	132,010,309 - 132,017,298 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	132,010,297 - 132,017,298 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	132,179,990 - 132,187,011 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	132,469,750 - 132,476,773 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	131,844,677 - 131,851,709 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	137,738,150 - 137,745,143 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	137,738,124 - 137,745,127 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	146,734,337 - 146,741,325 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	137,935,992 - 137,942,980 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	137,942,177 - 137,949,130 (-)	NCBI
Celera	6	129,548,189 - 129,555,177 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

Nudt14
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	3,444,591 - 3,450,194 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	3,444,498 - 3,450,396 (-)	NCBI	ChiLan1.0	ChiLan1.0

NUDT14
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	72,562,314 - 72,568,542 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	72,562,314 - 72,567,057 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	72,074,078 - 72,080,968 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	72,849,806 - 72,856,744 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	72,822,931 - 72,856,860 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	72,530,342 - 72,537,214 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	72,581,473 - 72,588,360 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	72,971,347 - 72,978,237 (-)	NCBI		UU_Cfam_GSD_1.0

Nudt14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	1,517,696 - 1,525,057 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936621	346,479 - 354,042 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936621	346,463 - 354,014 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUDT14
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	131,249,502 - 131,253,711 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103229796
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	83,082,072 - 83,090,373 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	83,081,793 - 83,090,316 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666500	42,686 - 50,979 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nudt14
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	298,357 - 304,048 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	288,223 - 304,136 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008959038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034938291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000018354 ⟹ ENSPPAP00000003958

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	14	105,600,783 - 105,605,538 (-)	Ensembl

RefSeq Acc Id:

XM_008959038 ⟹ XP_008957286

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	106,352,997 - 106,361,082 (-)	NCBI
NHGRI_mPanPan1	14	105,569,499 - 105,577,572 (-)	NCBI
Mhudiblu_PPA_v0	14	85,816,561 - 85,824,529 (-)	NCBI
PanPan1.1	14	105,600,783 - 105,608,697 (-)	NCBI

Sequence:

show sequence

TCAAGGAAGCATTGCTGGGCCCCATCCTTCCCGCCCGCCCAATCCGACCCTCTTGGCAGTGGAA
CTCCTTGGTTGCCCTGGGGATCAGGGAAGGCTTCCTGGAAGTGGTGGCTTTCATGCTACCACTT
GAAGGAGGAGATAGCTGGGCCGAGGAGGAAGGAGCAAGGAGTGCAGAGGCCGGGCGCAGAGAGA
ATGGTGCCCAGAAGTCCTGGGACTTCATGAAGACGCATGACAGCGTGACCGTTCTCTTATTCAA
CTCTTCTCGGAGGAGCCTGGTGTTGGTGAAGCAGTTCCGGCCAGCTGTGTATGCGGGTGAGGTG
GAGCGCCGCTTCCCAGGGTCCCTAGCAGCTGTAGACCAGGACGGGCCTCGGGAGCTACAGCCAG
CCCTGCCTGGCTCAGCGGGGGTGACAGTTGAGCTGTGTGCCGGCCTCGTGGACCAGCCTGGGCT
CTCGCTGGAGGAAGTGGCTTGCAAGGAGGCTTGGGAGGAGTGTGGCTACCACTTGGCCCCCTCT
GATCTGCGCCGGGTTGCCACATACTGGTCTGGAGTGGGACTGACTGGCTCCAGACAGACCATGT
TCTACACAGAGGTGACAGATGCCCAGCATAGCGGTCCAGGTGGGGGCCTGGTGGAGGAGGGTGA
GCTCATTGAGGTGGTGCACCTGCCCCTGGAAGGCGCCCAGGCCTTTGCAGACGACCCGGACATC
CCCAAGACCCTTGGCGTCATCTTTGGTGTCTCGTGGTTCCTCAGCCAGGTGGCCCCCAACCTGG
ATCTCCAGTGAGACTCCAGGGTTCTAGACAGAGGCCAGTCTTGGCCACTCACCCAACACCCCGC
GGACCCCAATAAAGGCTTGCATAGCTCCA

hide sequence

RefSeq Acc Id:

XM_034938291 ⟹ XP_034794182

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	15	106,352,997 - 106,361,331 (-)	NCBI
NHGRI_mPanPan1	14	105,569,499 - 105,577,835 (-)	NCBI
Mhudiblu_PPA_v0	14	85,816,561 - 85,824,887 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_008957286	(Get FASTA)	NCBI Sequence Viewer
	XP_034794182	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000003958
	ENSPPAP00000003958.1

RefSeq Acc Id:	XP_008957286 ⟸ XM_008959038
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZMF6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLPLEGGDSWAEEEGARSAEAGRRENGAQKSWDFMKTHDSVTVLLFNSSRRSLVLVKQFRPAVY AGEVERRFPGSLAAVDQDGPRELQPALPGSAGVTVELCAGLVDQPGLSLEEVACKEAWEECGYH LAPSDLRRVATYWSGVGLTGSRQTMFYTEVTDAQHSGPGGGLVEEGELIEVVHLPLEGAQAFAD DPDIPKTLGVIFGVSWFLSQVAPNLDLQ hide sequence

RefSeq Acc Id:	XP_034794182 ⟸ XM_034938291
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZMF6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSPPAP00000003958 ⟸ ENSPPAT00000018354

Protein Domains

Nudix hydrolase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000016772	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000018354.1	UniProtKB/TrEMBL
Gene3D-CATH	Nucleoside Triphosphate Pyrophosphohydrolase	UniProtKB/TrEMBL
InterPro	NDP_pyrophosphatase	UniProtKB/TrEMBL
	NUDIX_hydrolase-like_dom_sf	UniProtKB/TrEMBL
	NUDIX_hydrolase_dom	UniProtKB/TrEMBL
NCBI Gene	NUDT14	ENTREZGENE
PANTHER	UDP/ADP-SUGAR PYROPHOSPHATASE	UniProtKB/TrEMBL
	URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14	UniProtKB/TrEMBL
PROSITE	NUDIX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55811	UniProtKB/TrEMBL
UniProt	A0A2R8ZMF6	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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