NUP54 (nucleoporin 54) - Rat Genome Database

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Gene: NUP54 (nucleoporin 54) Pan paniscus
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Symbol: NUP54
Name: nucleoporin 54
RGD ID: 11728755
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN nucleocytoplasmic transport (ortholog); protein targeting (ortholog); regulation of protein import into nucleus (ortholog); PARTICIPATES IN mRNA nuclear export pathway; ASSOCIATED WITH dystonia 37, early-onset with striatal lesions (ortholog); genetic disease (ortholog); progressive myoclonus epilepsy (ortholog); FOUND IN nuclear envelope (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nucleoporin p54
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2353,924,149 - 53,958,784 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1454,113,869 - 54,150,174 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0448,057,553 - 48,091,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1453,896,058 - 53,929,596 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl453,896,058 - 53,929,596 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NUP54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2353,924,149 - 53,958,784 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1454,113,869 - 54,150,174 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0448,057,553 - 48,091,471 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1453,896,058 - 53,929,596 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl453,896,058 - 53,929,596 (+)Ensemblpanpan1.1panPan2
NUP54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38476,114,664 - 76,148,397 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl476,107,562 - 76,148,485 (-)EnsemblGRCh38hg38GRCh38
GRCh37477,035,817 - 77,069,550 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36477,254,841 - 77,288,679 (-)NCBINCBI36Build 36hg18NCBI36
Build 34477,392,996 - 77,426,834NCBI
Celera474,336,017 - 74,369,792 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef472,788,244 - 72,821,694 (-)NCBIHuRef
CHM1_1477,012,297 - 77,046,159 (-)NCBICHM1_1
T2T-CHM13v2.0479,455,330 - 79,489,069 (-)NCBIT2T-CHM13v2.0
Nup54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39592,563,399 - 92,583,117 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl592,563,399 - 92,583,078 (-)EnsemblGRCm39 Ensembl
GRCm38592,415,540 - 92,435,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl592,415,540 - 92,435,219 (-)EnsemblGRCm38mm10GRCm38
MGSCv37592,844,566 - 92,864,225 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36593,490,746 - 93,510,323 (-)NCBIMGSCv36mm8
Celera590,564,003 - 90,583,663 (-)NCBICelera
Cytogenetic Map5E2NCBI
cM Map546.75NCBI
Nup54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81415,901,936 - 15,920,335 (+)NCBIGRCr8
mRatBN7.21415,617,630 - 15,636,029 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1415,617,679 - 15,636,028 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1415,625,954 - 15,644,122 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01416,944,808 - 16,962,972 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01415,640,226 - 15,658,388 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01417,123,434 - 17,141,832 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1417,123,360 - 17,141,767 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01417,039,514 - 17,057,924 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41417,178,761 - 17,197,062 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11417,178,760 - 17,197,061 (+)NCBI
Celera1415,012,204 - 15,030,485 (+)NCBICelera
Cytogenetic Map14p22NCBI
Nup54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955433853,921 - 879,861 (-)NCBIChiLan1.0ChiLan1.0
NUP54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.132751,568 - 782,342 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl32751,982 - 782,314 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3241,100,154 - 41,131,148 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.032777,963 - 808,974 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl32777,883 - 808,921 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.132776,011 - 807,023 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.032730,301 - 761,292 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03239,408,219 - 39,439,234 (+)NCBIUU_Cfam_GSD_1.0
Nup54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528511,345,313 - 11,377,591 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936676133,782 - 161,938 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936676130,877 - 161,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl871,792,155 - 71,833,157 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1871,792,153 - 71,833,180 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2875,992,615 - 76,028,904 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUP54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1724,616,645 - 24,649,595 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl724,613,767 - 24,650,359 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660372,964,814 - 2,997,872 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475714,800,780 - 14,840,115 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000057891   ⟹   ENSPPAP00000035006
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl453,896,058 - 53,929,596 (+)Ensembl
RefSeq Acc Id: XM_003832292   ⟹   XP_003832340
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2353,924,149 - 53,958,784 (+)NCBI
NHGRI_mPanPan1454,113,869 - 54,148,535 (+)NCBI
Mhudiblu_PPA_v0448,057,553 - 48,091,471 (+)NCBI
PanPan1.1453,896,058 - 53,929,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034958626   ⟹   XP_034814517
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2353,924,888 - 53,958,784 (+)NCBI
NHGRI_mPanPan1454,114,608 - 54,150,171 (+)NCBI
Mhudiblu_PPA_v0448,057,571 - 48,091,471 (+)NCBI
RefSeq Acc Id: XM_034958627   ⟹   XP_034814518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2353,924,892 - 53,958,784 (+)NCBI
NHGRI_mPanPan1454,114,609 - 54,150,174 (+)NCBI
Mhudiblu_PPA_v0448,057,570 - 48,091,471 (+)NCBI
RefSeq Acc Id: XM_063603552   ⟹   XP_063459622
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2353,924,857 - 53,958,784 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003832340 (Get FASTA)   NCBI Sequence Viewer  
  XP_034814517 (Get FASTA)   NCBI Sequence Viewer  
  XP_034814518 (Get FASTA)   NCBI Sequence Viewer  
  XP_063459622 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035006
  ENSPPAP00000035006.1
RefSeq Acc Id: XP_003832340   ⟸   XM_003832292
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BZV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034814518   ⟸   XM_034958627
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034814517   ⟸   XM_034958626
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000035006   ⟸   ENSPPAT00000057891
RefSeq Acc Id: XP_063459622   ⟸   XM_063603552
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040336 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057891.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
InterPro Nup54/Nup57/Nup44 UniProtKB/TrEMBL
  Nup54_alpha-helical_dom UniProtKB/TrEMBL
  Nup54_C UniProtKB/TrEMBL
KEGG Report pps:100991609 UniProtKB/TrEMBL
NCBI Gene NUP54 ENTREZGENE
PANTHER NUCLEOPORIN P54 UniProtKB/TrEMBL
  PTHR13000 UniProtKB/TrEMBL
Pfam Nup54 UniProtKB/TrEMBL
  Nup54_C UniProtKB/TrEMBL
UniProt A0A2R9BZV1 ENTREZGENE, UniProtKB/TrEMBL