EVL (Enah/Vasp-like) - Rat Genome Database

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Gene: EVL (Enah/Vasp-like) Pan paniscus
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Symbol: EVL
Name: Enah/Vasp-like
RGD ID: 11728489
Description: ENCODES a protein that exhibits actin binding (inferred); profilin binding (inferred); SH3 domain binding (inferred); INVOLVED IN cellular response to type II interferon (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); genetic disease (ortholog); FOUND IN focal adhesion (ortholog); lamellipodium (ortholog); phagocytic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ena/VASP-like protein-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215101,125,411 - 101,298,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114100,341,906 - 100,514,669 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,594,889 - 80,767,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,959,668 - 100,084,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14100,005,645 - 100,084,598 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EVL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215101,125,411 - 101,298,175 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114100,341,906 - 100,514,669 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,594,889 - 80,767,652 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,959,668 - 100,084,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14100,005,645 - 100,084,598 (+)Ensemblpanpan1.1panPan2
EVL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,971,422 - 100,144,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,971,449 - 100,144,236 (+)EnsemblGRCh38hg38GRCh38
GRCh3714100,437,759 - 100,610,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361499,601,504 - 99,680,326 (+)NCBINCBI36Build 36hg18NCBI36
Celera1480,586,599 - 80,665,405 (+)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,713,940 - 80,792,633 (+)NCBIHuRef
CHM1_114100,469,494 - 100,548,295 (+)NCBICHM1_1
T2T-CHM13v2.01494,204,463 - 94,377,284 (+)NCBIT2T-CHM13v2.0
Evl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,520,942 - 108,654,775 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,520,979 - 108,654,775 (+)EnsemblGRCm39 Ensembl
GRCm3812108,554,681 - 108,688,516 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,554,720 - 108,688,516 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712109,792,930 - 109,926,726 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612109,002,527 - 109,136,323 (+)NCBIMGSCv36mm8
Celera12109,790,151 - 109,924,702 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.46NCBI
Evl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86133,238,547 - 133,358,730 (+)NCBIGRCr8
mRatBN7.26127,473,119 - 127,594,342 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,474,543 - 127,594,344 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6127,598,518 - 127,718,462 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06127,893,578 - 128,013,521 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06127,251,788 - 127,371,660 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06132,470,283 - 132,590,242 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6132,510,757 - 132,590,241 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06141,693,628 - 141,760,318 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,952,804 - 133,019,870 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16132,987,208 - 133,026,056 (+)NCBI
Celera6125,029,592 - 125,149,350 (+)NCBICelera
Cytogenetic Map6q32NCBI
Evl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543821,198,763 - 21,298,657 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543821,198,761 - 21,298,657 (+)NCBIChiLan1.0ChiLan1.0
EVL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1868,352,717 - 68,461,684 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl868,352,853 - 68,484,269 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,874,009 - 67,982,868 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,637,968 - 68,746,949 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,600,082 - 68,746,947 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1868,299,395 - 68,409,002 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0868,401,299 - 68,474,330 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,763,019 - 68,872,002 (+)NCBIUU_Cfam_GSD_1.0
Evl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,262,540 - 6,362,430 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,719,976 - 3,822,334 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,720,038 - 3,819,928 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EVL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,911,648 - 121,056,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,911,814 - 121,056,556 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27128,577,563 - 128,588,364 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EVL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,937,319 - 78,113,011 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2478,029,684 - 78,112,664 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605365,072,012 - 65,246,606 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Evl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247343,927,004 - 4,071,621 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247343,926,939 - 4,023,841 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000042654   ⟹   ENSPPAP00000019876
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14100,005,645 - 100,084,598 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000042661   ⟹   ENSPPAP00000019882
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14100,005,821 - 100,047,492 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000042676   ⟹   ENSPPAP00000019897
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14100,024,702 - 100,084,100 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000042683   ⟹   ENSPPAP00000019903
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14100,024,702 - 100,042,549 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000042688   ⟹   ENSPPAP00000019908
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl14100,024,920 - 100,084,100 (+)Ensembl
RefSeq Acc Id: XM_003832852   ⟹   XP_003832900
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,219,063 - 101,298,175 (+)NCBI
NHGRI_mPanPan114100,435,565 - 100,514,669 (+)NCBI
Mhudiblu_PPA_v01480,688,547 - 80,767,652 (+)NCBI
PanPan1.114100,005,645 - 100,084,598 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008958300   ⟹   XP_008956548
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,173,455 - 101,298,175 (+)NCBI
NHGRI_mPanPan114100,389,949 - 100,514,669 (+)NCBI
Mhudiblu_PPA_v01480,642,794 - 80,767,652 (+)NCBI
PanPan1.11499,959,668 - 100,084,598 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008958303   ⟹   XP_008956551
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,173,420 - 101,298,175 (+)NCBI
NHGRI_mPanPan114100,389,915 - 100,514,669 (+)NCBI
Mhudiblu_PPA_v01480,642,927 - 80,767,652 (+)NCBI
PanPan1.11499,959,698 - 100,084,598 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034938126   ⟹   XP_034794017
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,125,411 - 101,298,175 (+)NCBI
NHGRI_mPanPan114100,341,906 - 100,514,669 (+)NCBI
Mhudiblu_PPA_v01480,594,889 - 80,767,652 (+)NCBI
RefSeq Acc Id: XM_063596121   ⟹   XP_063452191
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,173,436 - 101,298,175 (+)NCBI
RefSeq Acc Id: XM_063596122   ⟹   XP_063452192
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,219,066 - 101,298,175 (+)NCBI
RefSeq Acc Id: XM_063596123   ⟹   XP_063452193
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,173,438 - 101,298,175 (+)NCBI
RefSeq Acc Id: XR_010109781
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v215101,173,440 - 101,295,109 (+)NCBI
RefSeq Acc Id: XP_008956548   ⟸   XM_008958300
- Peptide Label: isoform X4
- UniProtKB: A0A2R9ARV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008956551   ⟸   XM_008958303
- Peptide Label: isoform X7
- UniProtKB: A0A2R9ARV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003832900   ⟸   XM_003832852
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AR90 (UniProtKB/TrEMBL),   A0A2R9ARV1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034794017   ⟸   XM_034938126
- Peptide Label: isoform X6
- UniProtKB: A0A2R9ARV1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000019876   ⟸   ENSPPAT00000042654
RefSeq Acc Id: ENSPPAP00000019882   ⟸   ENSPPAT00000042661
RefSeq Acc Id: ENSPPAP00000019897   ⟸   ENSPPAT00000042676
RefSeq Acc Id: ENSPPAP00000019908   ⟸   ENSPPAT00000042688
RefSeq Acc Id: ENSPPAP00000019903   ⟸   ENSPPAT00000042683
RefSeq Acc Id: XP_063452191   ⟸   XM_063596121
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063452193   ⟸   XM_063596123
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063452192   ⟸   XM_063596122
- Peptide Label: isoform X2
Protein Domains
WH1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033126 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042654.1 UniProtKB/TrEMBL
  ENSPPAT00000042661.1 UniProtKB/TrEMBL
  ENSPPAT00000042676.1 UniProtKB/TrEMBL
  ENSPPAT00000042683.1 UniProtKB/TrEMBL
  ENSPPAT00000042688.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  VASP/EVL UniProtKB/TrEMBL
  VASP_sf UniProtKB/TrEMBL
  VASP_tetra UniProtKB/TrEMBL
  WH1/EVH1_dom UniProtKB/TrEMBL
KEGG Report pps:100979361 UniProtKB/TrEMBL
NCBI Gene EVL ENTREZGENE
PANTHER PTHR11202:SF4 UniProtKB/TrEMBL
  SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam VASP_tetra UniProtKB/TrEMBL
  WH1 UniProtKB/TrEMBL
PIRSF Vasodilator_Phospo UniProtKB/TrEMBL
PROSITE WH1 UniProtKB/TrEMBL
SMART WH1 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF118370 UniProtKB/TrEMBL
UniProt A0A2R9AR90 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AR92_PANPA UniProtKB/TrEMBL
  A0A2R9ARA5_PANPA UniProtKB/TrEMBL
  A0A2R9ARU6_PANPA UniProtKB/TrEMBL
  A0A2R9ARV1 ENTREZGENE, UniProtKB/TrEMBL