GRK5 (G protein-coupled receptor kinase 5)

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Gene: GRK5 (G protein-coupled receptor kinase 5) Pan paniscus

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Symbol:

GRK5

Name:

G protein-coupled receptor kinase 5

RGD ID:

11726087

Description:

ENCODES a protein that exhibits ATP binding (inferred); beta-adrenergic receptor kinase activity (inferred); G protein-coupled receptor kinase activity (inferred); INVOLVED IN desensitization of G protein-coupled receptor signaling pathway (ortholog); fat cell differentiation (ortholog); negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; dopamine signaling pathway via D1 family of receptors; ASSOCIATED WITH Alzheimer's disease (ortholog); cardiovascular system disease (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nuclear membrane (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	131,064,338 - 131,314,329 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	131,069,692 - 131,319,683 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	115,776,236 - 116,026,221 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	119,200,901 - 119,448,006 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	119,200,688 - 119,450,809 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

cardiovascular system disease (ISO)

Cocaine-Related Disorders (ISO)

congestive heart failure (ISO)

hypertension (ISO)

Inflammation (ISO)

liver disease (ISO)

obstructive lung disease (ISO)

Parkinson's disease (ISO)

rheumatoid arthritis (ISO)

Sepsis (ISO)

Temporomandibular Joint Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

desensitization of G protein-coupled receptor signaling pathway (ISO)

fat cell differentiation (ISO)

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (ISO)

negative regulation of apoptotic process (IEA)

oligodendrocyte differentiation (ISO)

positive regulation of cell population proliferation (IEA)

protein autophosphorylation (ISO)

regulation of cell cycle (IEA)

regulation of G protein-coupled receptor signaling pathway (ISO)

regulation of signal transduction (IEA)

response to cocaine (ISO)

signal transduction (IEA)

tachykinin receptor signaling pathway (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA)

nuclear membrane (IEA)

nuclear speck (IEA)

plasma membrane (IEA)

Molecular Function

ATP binding (IEA)

beta-adrenergic receptor kinase activity (IEA)

G protein-coupled receptor kinase activity (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylcholine signaling pathway via muscarinic acetylcholine receptor (ISO)

angiotensin II signaling pathway via AT1 receptor (ISO)

dopamine signaling pathway via D1 family of receptors (ISO)

dopamine signaling pathway via D2 family of receptors (ISO)

epinephrine signaling pathway via adrenergic receptor beta (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GRK5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	131,064,338 - 131,314,329 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	131,069,692 - 131,319,683 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	115,776,236 - 116,026,221 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	119,200,901 - 119,448,006 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	119,200,688 - 119,450,809 (+)	Ensembl	panpan1.1		panPan2

GRK5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	119,207,571 - 119,459,745 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	119,207,571 - 119,459,745 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	120,967,083 - 121,219,257 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	120,957,187 - 121,205,121 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	120,957,186 - 121,205,120	NCBI
Celera	10	114,696,799 - 114,943,133 (+)	NCBI		Celera
Cytogenetic Map	10	q26.11	NCBI
HuRef	10	114,596,405 - 114,842,644 (+)	NCBI		HuRef
CHM1_1	10	121,251,583 - 121,499,541 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	120,102,994 - 120,355,311 (+)	NCBI		T2T-CHM13v2.0

Grk5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	60,877,995 - 61,084,406 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	60,878,187 - 61,084,406 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	60,889,560 - 61,095,968 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	60,889,749 - 61,095,968 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	60,965,652 - 61,168,459 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	60,945,139 - 61,147,005 (+)	NCBI		MGSCv36	mm8
Celera	19	63,189,741 - 63,294,504 (+)	NCBI		Celera
Cytogenetic Map	19	D3	NCBI
cM Map	19	56.52	NCBI

Grk5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	270,014,314 - 270,208,294 (+)	NCBI		GRCr8
mRatBN7.2	1	260,028,269 - 260,223,699 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	260,028,242 - 260,218,701 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	268,234,940 - 268,425,947 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	274,940,966 - 275,131,956 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	267,595,271 - 267,786,197 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	282,265,371 - 282,467,842 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	282,265,370 - 282,462,605 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	289,603,922 - 289,802,914 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	267,495,534 - 267,693,144 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	267,706,618 - 267,904,229 (+)	NCBI
Celera	1	255,668,943 - 255,859,242 (+)	NCBI		Celera
Cytogenetic Map	1	q55	NCBI

Grk5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955551	44,156 - 254,534 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955551	43,918 - 255,118 (+)	NCBI	ChiLan1.0	ChiLan1.0

GRK5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	28	29,424,350 - 29,636,552 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	28	29,424,593 - 29,632,741 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	28	29,566,413 - 29,778,694 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	28	29,955,098 - 30,167,121 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	28	29,955,134 - 30,165,427 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	28	29,509,598 - 29,721,404 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	28	29,529,525 - 29,741,448 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	28	29,723,728 - 29,936,023 (+)	NCBI		UU_Cfam_GSD_1.0

Grk5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	16,730,225 - 16,924,264 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936486	8,720,036 - 8,831,075 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936486	8,720,036 - 8,830,472 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GRK5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	129,113,603 - 129,347,152 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	129,113,933 - 129,351,135 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	140,638,292 - 140,875,396 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GRK5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	111,996,780 - 112,249,247 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	111,996,599 - 112,244,570 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	73,269,146 - 73,517,028 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Grk5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624737	27,375,149 - 27,600,210 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624737	27,379,114 - 27,600,132 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003825647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063607919	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000033345 ⟹ ENSPPAP00000010692

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	119,200,688 - 119,450,809 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000033350 ⟹ ENSPPAP00000010697

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	119,412,204 - 119,447,448 (+)	Ensembl

RefSeq Acc Id:

XM_003825647 ⟹ XP_003825695

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	131,064,338 - 131,314,329 (+)	NCBI
NHGRI_mPanPan1	10	131,069,692 - 131,319,683 (+)	NCBI
Mhudiblu_PPA_v0	10	115,776,236 - 116,026,221 (+)	NCBI
PanPan1.1	10	119,200,901 - 119,448,006 (+)	NCBI

Sequence:

show sequence

GAGCGTGTTGGAGGGGAGGGGGGAGGGGGACACAGAGGGAGGAAGAAGCGGCGGCGGCGGCGGC
GGCGGCTCCTCTTTGCAGAGGGGGAAACTCTTGGGCTGAGAGCAGGAATAATGCGGTAGGCAAG
GCGGGCTGCTGGCTCCCCCGGCTCCGGCAGCAGCGGCGGCAGCCCGAGCAGCGGCAGCAGCAGC
GGCAGCACCCCAGGCGCTGACAGCCCCGCCGGCCGGCTCCGTTGCTGACCGCCGACTGTCAATG
GAGCTGGAAAACATCGTGGCCAACACGGTCTTGCTGAAAGCCAGGGAAGGGGGCGGAGGAAAGC
GCAAAGGGAAAAGCAAGAAGTGGAAAGAAATCCTGAAGTTCCCTCACATTAGCCAGTGTGAAGA
CCTCCGAAGGACCATAGACAGAGATTACTGCAGTTTATGTGACAAGCAGCCAATTGGGAGGCTG
CTTTTCCGGCAGTTTTGTGAAACCAGGCCTGGGCTGGAGTGTTACATTCAGTTCCTGGACTCCG
TGGCAGAATATGAAGTTACTCCAGATGAAAAACTGGGAGAGAAAGGGAAGGAAATTATGACCAA
GTACCTCACCCCAAAGTCCCCTGTTTTCATAGCCCAAGTTGGCCAAGACCTGGTCTCCCAGACG
GAGGAGAAGCTCCTGCAGAAGCCGTGCAAAGAACTCTTTTCTGCCTGTGCACAGTCTGTCCACG
AGTACCTGAGGGGAGAACCATTCCACGAATATCTGGACAGCATGTATTTTGACCGCTTTCTCCA
GTGGAAGTGGTTGGAAAGGCAACCGGTGACCAAAAACACTTTCAGGCAGTATCGAGTGCTAGGA
AAAGGGGGCTTCGGGGAGGTCTGTGCCTGCCAGGTTCGGGCCACGGGTAAAATGTATGCCTGCA
AGCGCTTGGAGAAGAAGAGGATCAAAAAGAGGAAAGGGGAGTCCATGGCCCTCAACGAGAAGCA
GATCCTCGAGAAGGTCAACAGTCAGTTTGTGGTCAACCTGGCCTATGCCTACGAGACCAAGGAT
GCACTGTGCTTGGTCTTGACCATCATGAATGGGGGTGACCTGAAGTTCCACATCTACAACATGG
GCAACCCCGGCTTCGAGGAGGAGCGGGCCTTGTTTTATGCGGCAGAGATCCTCTGCGGCTTGGA
AGACCTCCACCGTGAGAACACCGTCTACCGAGATCTGAAACCTGAAAACATCCTGTTAGATGAT
TATGGCCACATTAGGATCTCAGACCTGGGCTTGGCTGTGAAGATCCCCGAGGGAGACCTGATCC
GCGGCCGGGTGGGCACTGTTGGCTACATGGCTCCAGAGGTCCTGAACAACCAGAGGTACGGCCT
GAGCCCCGACTACTGGGGCCTTGGCTGCCTCATCTATGAGATGATCGAGGGCCAGTCGCCGTTC
CGCGGCCGCAAGGAGAAGGTGAAGCGGGAGGAGGTGGACCGCCGGGTCCTGGAGACGGAGGAGG
TGTACTCCCACAAGTTCTCCGAGGAGGCCAAGTCCATCTGCAAGATGCTGCTCACGAAAGATGC
GAAGCAGAGGCTGGGCTGCCAGGAGGAGGGGGCTGCAGAGGTCAAGAGACACCCCTTCTTCAGG
AACATGAACTTCAAGCGCTTAGAAGCCGGGATGTTGGACCCTCCCTTTGTTCCAGACCCCCGCG
CTGTGTACTGTAAGGACGTGCTGGACATCGAGCAGTTCTCCACTGTGAAGGGCGTCAATCTGGA
CCACACAGACGACGACTTCTACTCCAAGTTCTCCACGGGCTCTGTGTCCATCCCGTGGCAAAAC
GAGATGATAGAAACAGAATGCTTTAAGGAGCTGAACGTGTTTGGACCTAATGGTACCCTCTCGC
CAGATCTGAACAGAAACCACCCTCCGGAACCGCCCAAGAAAGGGCTGCTCCAGAGACTCTTCAA
GCGGCAGCATCAGAACAATTCCAAGAGTTCGCCCAGCTCCAAGACCAGTTTTAACCACCACATA
AACTCAAACCACGTCAGCTCGAACTCCACCGGAAGCAGCTAGTTTCGGCTCTGGCCTCCAAGTC
CACAGTGGAACCAGCCCAGACCCTTCTCCTTAGAAGCGGAAGTAGTGGAGCCCCTGCTCTGGTG
GGGCTGCCAGGGGAGCCCCCCGGGAGCCGGTGAAGGAGGCCGTCCATCCCGTCGACGTAGAACC
TCGAGGTTTCTCAAAGAAATTTCCACTCAGGTCTGTTTTCCGAGGCGGCCCCGGCCGGGGTGGA
TTGGATTTGTCTTTGGTGAACATTGCAATAGAAATCCAATTGGATACGACAACTTGCACGTATT
TTAATAGCGTCATAACTAGAACTGAATTTTGTCTTTATGATTTTTAAAGAAAAGTTTTGTAAAT
TTCTCTACTGTCTCAGTTTACATTTTGTATATTTGTATTTAAATGAAAGTGAGACTTTGAGGGT
GTATATTTTCTGTGCAGCCACTGTTAAGCCATGTGTTCCAAGGCATTTTAGCGGGGAGGGGGTT
ATCCAAAAAAAAAAAAAATGTGACTCAAGACTTCCAGAGCCTCAAATGAGAAAATGTCTTTATT
AAATGTAGAAAGTGATCCACACTT

hide sequence

RefSeq Acc Id:

XM_034931601 ⟹ XP_034787492

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	131,064,344 - 131,314,329 (+)	NCBI
NHGRI_mPanPan1	10	131,069,822 - 131,319,473 (+)	NCBI
Mhudiblu_PPA_v0	10	115,776,337 - 116,026,221 (+)	NCBI

RefSeq Acc Id:

XM_063607919 ⟹ XP_063463989

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	131,064,443 - 131,314,329 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003825695	(Get FASTA)	NCBI Sequence Viewer
	XP_034787492	(Get FASTA)	NCBI Sequence Viewer
	XP_063463989	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000010692
	ENSPPAP00000010692.1
	ENSPPAP00000010697.1

RefSeq Acc Id:	XP_003825695 ⟸ XM_003825647
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9A0D5 (UniProtKB/TrEMBL), A0A2R9A0E3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPIGR LLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQVGQDLVSQ TEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMYFDRFLQWKWLERQPVTKNTFRQYRVL GKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSQFVVNLAYAYETK DALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLD DYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSP FRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFF RNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDIEQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQ NEMIETECFKELNVFGPNGTLSPDLNRNHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTSFNHH INSNHVSSNSTGSS hide sequence

RefSeq Acc Id:	XP_034787492 ⟸ XM_034931601
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSPPAP00000010692 ⟸ ENSPPAT00000033345

Ensembl Acc Id:

ENSPPAP00000010697 ⟸ ENSPPAT00000033350

RefSeq Acc Id:	XP_063463989 ⟸ XM_063607919
- Peptide Label:	isoform X3

Protein Domains

AGC-kinase C-terminal Protein kinase RGS

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000028552	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000033345.1	UniProtKB/TrEMBL
	ENSPPAT00000033350.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.167.10	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	AGC-kinase_C	UniProtKB/TrEMBL
	GPCR_kinase	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
	RGS_sf	UniProtKB/TrEMBL
	RGS_subdomain_2	UniProtKB/TrEMBL
KEGG Report	pps:100975050	UniProtKB/TrEMBL
NCBI Gene	GRK5	ENTREZGENE
PANTHER	G PROTEIN-COUPLED RECEPTOR KINASE 5	UniProtKB/TrEMBL
	G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
PRINTS	GPCRKINASE	UniProtKB/TrEMBL
PROSITE	AGC_KINASE_CTER	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	RGS	UniProtKB/TrEMBL
SMART	RGS	UniProtKB/TrEMBL
	S_TK_X	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48097	UniProtKB/TrEMBL
	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9A0D5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A0E3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - CTD

RGD Manual Annotations