ST8SIA6 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6) - Rat Genome Database

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Gene: ST8SIA6 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6) Pan paniscus
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Symbol: ST8SIA6
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
RGD ID: 11724454
Description: ENCODES a protein that exhibits alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity (inferred); sialyltransferase activity (inferred); transferase activity (inferred); INVOLVED IN blastocyst hatching (ortholog); carbohydrate biosynthetic process (ortholog); glycolipid biosynthetic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-2,8-sialyltransferase 8F
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,157,749 - 30,296,661 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,163,078 - 30,301,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,632,154 - 17,771,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11017,908,992 - 18,042,179 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1017,909,556 - 18,041,946 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ST8SIA6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2830,157,749 - 30,296,661 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11030,163,078 - 30,301,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,632,154 - 17,771,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11017,908,992 - 18,042,179 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1017,909,556 - 18,041,946 (-)Ensemblpanpan1.1panPan2
ST8SIA6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,315,421 - 17,454,595 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,315,421 - 17,454,595 (-)EnsemblGRCh38hg38GRCh38
GRCh371017,357,420 - 17,496,594 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,402,682 - 17,536,260 (-)NCBINCBI36Build 36hg18NCBI36
Celera1017,295,946 - 17,429,480 (-)NCBICelera
Cytogenetic Map10p12.33NCBI
HuRef1017,275,955 - 17,409,503 (-)NCBIHuRef
CHM1_11017,363,085 - 17,496,601 (-)NCBICHM1_1
T2T-CHM13v2.01017,333,849 - 17,473,031 (-)NCBIT2T-CHM13v2.0
St8sia6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39213,659,745 - 13,798,659 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl213,655,832 - 13,798,875 (-)EnsemblGRCm39 Ensembl
GRCm38213,651,018 - 13,794,734 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl213,651,021 - 13,794,064 (-)EnsemblGRCm38mm10GRCm38
MGSCv37213,576,561 - 13,715,147 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,572,787 - 13,711,274 (-)NCBIMGSCv36mm8
Celera213,563,519 - 13,699,249 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map210.09NCBI
St8sia6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81781,649,866 - 81,847,970 (-)NCBIGRCr8
mRatBN7.21776,740,755 - 76,884,178 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1776,745,224 - 76,884,299 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,220,377 - 80,344,118 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01784,055,770 - 84,179,521 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01778,103,669 - 78,227,420 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01780,960,785 - 81,002,830 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1780,960,785 - 81,002,838 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,587,821 - 82,756,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41787,927,956 - 88,070,368 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11787,938,788 - 88,081,201 (-)NCBI
Celera1776,117,552 - 76,241,106 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
St8sia6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,538,661 - 10,658,008 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,538,660 - 10,660,493 (+)NCBIChiLan1.0ChiLan1.0
ST8SIA6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,392,690 - 19,618,127 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,482,468 - 19,616,339 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,585,594 - 16,719,315 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0219,773,544 - 19,907,512 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,773,544 - 19,909,106 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1216,976,396 - 17,110,191 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0217,811,908 - 17,947,997 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,431,883 - 18,566,169 (+)NCBIUU_Cfam_GSD_1.0
St8sia6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934417,966,001 - 18,090,919 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365209,869,195 - 9,988,541 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365209,869,166 - 9,990,205 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST8SIA6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,602,908 - 43,755,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,601,677 - 43,755,154 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,311,195 - 48,393,885 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ST8SIA6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,269,548 - 17,400,860 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605122,908,115 - 23,043,088 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St8sia6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,458,466 - 10,570,959 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,383,947 - 10,577,117 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000013497   ⟹   ENSPPAP00000002865
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1017,909,556 - 18,041,946 (-)Ensembl
RefSeq Acc Id: XM_034930052   ⟹   XP_034785943
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2830,157,749 - 30,296,661 (-)NCBI
NHGRI_mPanPan11030,163,078 - 30,301,982 (-)NCBI
Mhudiblu_PPA_v01017,632,154 - 17,771,102 (-)NCBI
RefSeq Acc Id: XM_055092447   ⟹   XP_054948422
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2830,157,749 - 30,296,438 (-)NCBI
NHGRI_mPanPan11030,163,078 - 30,301,759 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034785943 (Get FASTA)   NCBI Sequence Viewer  
  XP_054948422 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000002865.1
RefSeq Acc Id: XP_034785943   ⟸   XM_034930052
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZCT3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000002865   ⟸   ENSPPAT00000013497
RefSeq Acc Id: XP_054948422   ⟸   XM_055092447
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000012351 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000013497.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/TrEMBL
NCBI Gene ST8SIA6 ENTREZGENE
PANTHER ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/TrEMBL
  ALPHA-2,8-SIALYLTRANSFERASE 8F UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/TrEMBL
PIRSF Sialyl_trans UniProtKB/TrEMBL
UniProt A0A2R8ZCT3 ENTREZGENE, UniProtKB/TrEMBL