SOSTDC1 (sclerostin domain containing 1) - Rat Genome Database
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Gene: SOSTDC1 (sclerostin domain containing 1) Pan paniscus
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Symbol: SOSTDC1
Name: sclerostin domain containing 1
RGD ID: 11721783
Description: ENCODES a protein that exhibits BMP binding (ortholog); BMP receptor activity (ortholog); INVOLVED IN hair follicle morphogenesis (ortholog); mammary gland bud morphogenesis (ortholog); negative regulation of BMP signaling pathway (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy A7 (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: sclerostin domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1716,443,703 - 16,448,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,443,703 - 16,448,076 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0717,116,828 - 17,121,142 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
SOSTDC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1716,443,703 - 16,448,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,443,703 - 16,448,076 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0717,116,828 - 17,121,142 (-)NCBIMhudiblu_PPA_v0panPan3
SOSTDC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl716,461,481 - 16,530,580 (-)EnsemblGRCh38hg38GRCh38
GRCh38716,461,481 - 16,465,738 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37716,501,106 - 16,505,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36716,467,631 - 16,471,999 (-)NCBINCBI36hg18NCBI36
Build 34716,274,347 - 16,278,714NCBI
Celera716,480,854 - 16,485,222 (-)NCBI
Cytogenetic Map7p21.2NCBI
HuRef716,387,637 - 16,392,005 (-)NCBIHuRef
CHM1_1716,500,852 - 16,505,220 (-)NCBICHM1_1
CRA_TCAGchr7v2716,554,239 - 16,558,607 (-)NCBI
Sostdc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391236,364,168 - 36,368,451 (+)NCBIGRCm39mm39
GRCm39 Ensembl1236,364,138 - 36,368,451 (+)Ensembl
GRCm381236,314,169 - 36,318,452 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1236,314,139 - 36,318,452 (+)EnsemblGRCm38mm10GRCm38
MGSCv371237,040,756 - 37,045,039 (+)NCBIGRCm37mm9NCBIm37
MGSCv361236,824,492 - 36,828,711 (+)NCBImm8
Celera1237,763,054 - 37,767,254 (+)NCBICelera
Cytogenetic Map12A3NCBI
Sostdc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2653,051,336 - 53,055,510 (+)NCBI
Rnor_6.0 Ensembl655,812,747 - 55,817,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0655,812,820 - 55,816,994 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0665,423,740 - 65,427,914 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4655,066,277 - 55,070,451 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1655,069,402 - 55,073,577 (+)NCBI
Celera652,193,795 - 52,197,969 (+)NCBICelera
Cytogenetic Map6q16NCBI
Sostdc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541019,657,029 - 19,662,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541019,657,805 - 19,662,121 (-)NCBIChiLan1.0ChiLan1.0
SOSTDC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1431,022,766 - 31,026,737 (-)NCBICanFam3.1canFam3CanFam3.1
CanFam3.11431,035,759 - 31,079,139 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Sostdc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365462,976,045 - 2,980,487 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOSTDC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl985,743,335 - 85,747,591 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1985,743,332 - 85,747,893 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2994,581,754 - 94,585,919 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOSTDC1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12141,645,884 - 41,651,360 (+)NCBI
ChlSab1.1 Ensembl2141,647,079 - 41,652,093 (+)Ensembl
Sostdc1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473913,767,523 - 13,771,708 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008978702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000045408   ⟹   ENSPPAP00000022597
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,443,703 - 16,448,076 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000045411   ⟹   ENSPPAP00000022600
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,444,775 - 16,447,887 (-)Ensembl
RefSeq Acc Id: XM_008978702   ⟹   XP_008976950
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1716,443,703 - 16,448,076 (-)NCBI
Mhudiblu_PPA_v0717,116,828 - 17,121,142 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008976950 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008976950   ⟸   XM_008978702
- Sequence:
RefSeq Acc Id: ENSPPAP00000022597   ⟸   ENSPPAT00000045408
RefSeq Acc Id: ENSPPAP00000022600   ⟸   ENSPPAT00000045411
Protein Domains
CTCK


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034484 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022597 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000022600 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045408 UniProtKB/TrEMBL
  ENSPPAT00000045411 UniProtKB/TrEMBL
Gene3D-CATH 2.10.90.10 UniProtKB/TrEMBL
InterPro Cys_knot_C UniProtKB/TrEMBL
  Cystine-knot_cytokine UniProtKB/TrEMBL
  Sclerostin/SOSTDC1 UniProtKB/TrEMBL
KEGG Report pps:100991326 UniProtKB/TrEMBL
NCBI Gene SOSTDC1 ENTREZGENE
PANTHER PTHR14903 UniProtKB/TrEMBL
Pfam Sclerostin UniProtKB/TrEMBL
PROSITE CTCK_2 UniProtKB/TrEMBL
UniProt A0A2R9AZE5_PANPA UniProtKB/TrEMBL
  A0A2R9B357_PANPA UniProtKB/TrEMBL