SRSF5 (serine and arginine rich splicing factor 5) - Rat Genome Database

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Gene: SRSF5 (serine and arginine rich splicing factor 5) Pan paniscus
Analyze
Symbol: SRSF5
Name: serine and arginine rich splicing factor 5
RGD ID: 11715426
Description: ENCODES a protein that exhibits protein kinase B binding (ortholog); RNA binding (ortholog); RS domain binding (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); liver development (ortholog); liver regeneration (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH breast cancer (ortholog); clear cell renal cell carcinoma (ortholog); colon adenocarcinoma (ortholog); FOUND IN nuclear speck (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/arginine-rich splicing factor 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21570,851,134 - 70,896,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11470,067,686 - 70,112,551 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01450,320,820 - 50,365,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11469,230,730 - 69,236,596 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1469,230,730 - 69,236,596 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nuclear speck  (ISO)
nucleolus  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SRSF5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21570,851,134 - 70,896,038 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11470,067,686 - 70,112,551 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01450,320,820 - 50,365,650 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11469,230,730 - 69,236,596 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1469,230,730 - 69,236,596 (+)Ensemblpanpan1.1panPan2
SRSF5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381469,767,142 - 69,772,005 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1469,726,900 - 69,772,005 (+)EnsemblGRCh38hg38GRCh38
GRCh371470,233,859 - 70,238,722 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361469,303,582 - 69,308,475 (+)NCBINCBI36Build 36hg18NCBI36
Build 341469,303,562 - 69,308,474NCBI
Celera1450,297,941 - 50,302,834 (+)NCBICelera
Cytogenetic Map14q24.1NCBI
HuRef1450,402,386 - 50,407,279 (+)NCBIHuRef
CHM1_11470,171,971 - 70,176,864 (+)NCBICHM1_1
T2T-CHM13v2.01463,934,566 - 63,979,677 (+)NCBIT2T-CHM13v2.0
Srsf5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391280,992,308 - 80,997,277 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1280,992,278 - 80,997,281 (+)EnsemblGRCm39 Ensembl
GRCm381280,945,495 - 80,950,507 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1280,945,504 - 80,950,507 (+)EnsemblGRCm38mm10GRCm38
MGSCv371282,046,491 - 82,051,494 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361281,865,424 - 81,869,347 (+)NCBIMGSCv36mm8
Celera1282,411,025 - 82,416,029 (+)NCBICelera
Cytogenetic Map12D1NCBI
cM Map1237.2NCBI
Srsf5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86106,333,998 - 106,341,467 (+)NCBIGRCr8
mRatBN7.26100,605,165 - 100,610,192 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6100,605,456 - 100,610,177 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6100,766,147 - 100,770,857 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06101,065,329 - 101,070,039 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06100,445,515 - 100,450,226 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06104,611,026 - 104,640,033 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6104,611,026 - 104,615,302 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01721,149,626 - 21,149,932 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.06112,776,230 - 112,805,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46104,728,286 - 104,732,982 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16104,731,761 - 104,736,439 (+)NCBI
Celera698,461,136 - 98,465,890 (+)NCBICelera
Cytogenetic Map6q24NCBI
Srsf5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955466612,221 - 617,753 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955466612,221 - 617,087 (-)NCBIChiLan1.0ChiLan1.0
SRSF5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1843,514,048 - 43,519,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl843,514,076 - 43,518,481 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha843,202,998 - 43,207,951 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0843,742,032 - 43,746,990 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl843,742,032 - 43,746,989 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1843,356,400 - 43,361,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0843,430,128 - 43,435,082 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0843,790,108 - 43,795,064 (+)NCBIUU_Cfam_GSD_1.0
Srsf5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864061,234,058 - 61,239,077 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649512,952,646 - 12,960,681 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649512,952,610 - 12,957,640 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRSF5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl793,393,426 - 93,403,011 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1793,393,379 - 93,398,510 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2799,667,698 - 99,676,353 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SRSF5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12447,009,211 - 47,014,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2447,009,122 - 47,013,644 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605335,235,478 - 35,241,387 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srsf5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473431,309,656 - 31,314,891 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473431,309,647 - 31,314,923 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000036191   ⟹   ENSPPAP00000013519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1469,230,730 - 69,236,596 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036216   ⟹   ENSPPAP00000013544
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1469,232,745 - 69,236,050 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036219   ⟹   ENSPPAP00000013547
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1469,232,745 - 69,234,149 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000036220   ⟹   ENSPPAP00000013548
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1469,232,745 - 69,233,714 (+)Ensembl
RefSeq Acc Id: XM_008977815   ⟹   XP_008976063
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,851,134 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,067,686 - 70,112,551 (+)NCBI
Mhudiblu_PPA_v01450,320,820 - 50,365,650 (+)NCBI
PanPan1.11469,230,730 - 69,236,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008977816   ⟹   XP_008976064
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,109 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,662 - 70,112,551 (+)NCBI
Mhudiblu_PPA_v01450,360,762 - 50,365,650 (+)NCBI
PanPan1.11469,231,704 - 69,236,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008977817   ⟹   XP_008976065
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,040 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,784 - 70,112,551 (+)NCBI
Mhudiblu_PPA_v01450,360,813 - 50,365,650 (+)NCBI
PanPan1.11469,231,725 - 69,236,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008977818   ⟹   XP_008976066
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,134 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,647 - 70,112,551 (+)NCBI
Mhudiblu_PPA_v01450,360,765 - 50,365,650 (+)NCBI
PanPan1.11469,231,705 - 69,236,596 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055097736   ⟹   XP_054953711
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,152 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,784 - 70,112,551 (+)NCBI
RefSeq Acc Id: XM_055097737   ⟹   XP_054953712
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,149 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,662 - 70,112,551 (+)NCBI
RefSeq Acc Id: XM_055097738   ⟹   XP_054953713
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,146 - 70,893,815 (+)NCBI
NHGRI_mPanPan11470,107,784 - 70,111,021 (+)NCBI
RefSeq Acc Id: XM_063596088   ⟹   XP_063452158
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,134 - 70,893,815 (+)NCBI
RefSeq Acc Id: XR_008620907
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,134 - 70,896,038 (+)NCBI
NHGRI_mPanPan11470,107,647 - 70,112,551 (+)NCBI
RefSeq Acc Id: XR_010109766
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,152 - 70,896,038 (+)NCBI
RefSeq Acc Id: XR_010109767
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21570,891,150 - 70,896,038 (+)NCBI
RefSeq Acc Id: XP_008976063   ⟸   XM_008977815
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A8C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976064   ⟸   XM_008977816
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A8C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008976066   ⟸   XM_008977818
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008976065   ⟸   XM_008977817
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A8C0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000013547   ⟸   ENSPPAT00000036219
RefSeq Acc Id: ENSPPAP00000013544   ⟸   ENSPPAT00000036216
RefSeq Acc Id: ENSPPAP00000013548   ⟸   ENSPPAT00000036220
RefSeq Acc Id: ENSPPAP00000013519   ⟸   ENSPPAT00000036191
RefSeq Acc Id: XP_054953712   ⟸   XM_055097737
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054953711   ⟸   XM_055097736
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054953713   ⟸   XM_055097738
- Peptide Label: isoform X3
- UniProtKB: A0A2R9ADM0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452158   ⟸   XM_063596088
- Peptide Label: isoform X3
- UniProtKB: A0A2R9ADM0 (UniProtKB/TrEMBL)
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029921 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036191.1 UniProtKB/TrEMBL
  ENSPPAT00000036216.1 UniProtKB/TrEMBL
  ENSPPAT00000036219.1 UniProtKB/TrEMBL
  ENSPPAT00000036220.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report pps:100985817 UniProtKB/TrEMBL
NCBI Gene SRSF5 ENTREZGENE
PANTHER RIBONUCLEOPROTEIN RB97D UniProtKB/TrEMBL
  RIBONUCLEOPROTEIN RB97D UniProtKB/TrEMBL
  RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  RRM DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A2R9A8C0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A8D6_PANPA UniProtKB/TrEMBL
  A0A2R9ADH1_PANPA UniProtKB/TrEMBL
  A0A2R9ADM0 ENTREZGENE, UniProtKB/TrEMBL