BCO2 (beta-carotene oxygenase 2) - Rat Genome Database

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Gene: BCO2 (beta-carotene oxygenase 2) Pan paniscus
Analyze
Symbol: BCO2
Name: beta-carotene oxygenase 2
RGD ID: 11711313
Description: ENCODES a protein that exhibits beta,beta-carotene-9',10'-cleaving oxygenase activity (inferred); beta-carotene 15,15'-dioxygenase activity (inferred); carotenoid dioxygenase activity (inferred); INVOLVED IN retinal metabolic process (ortholog); xanthophyll metabolic process (ortholog); ASSOCIATED WITH BH4-deficient hyperphenylalaninemia A (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); hepatocellular carcinoma (ortholog); FOUND IN mitochondrion (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta,beta-carotene 9',10'-oxygenase; carotenoid-cleaving dioxygenase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29112,920,417 - 112,971,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111114,015,150 - 114,065,619 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011107,056,525 - 107,105,358 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111110,899,703 - 110,942,556 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,899,703 - 110,942,547 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
BCO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29112,920,417 - 112,971,307 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111114,015,150 - 114,065,619 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011107,056,525 - 107,105,358 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111110,899,703 - 110,942,556 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11110,899,703 - 110,942,547 (+)Ensemblpanpan1.1panPan2
BCO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811112,175,512 - 112,218,946 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11112,175,510 - 112,224,699 (+)EnsemblGRCh38hg38GRCh38
GRCh3711112,046,235 - 112,089,669 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611111,551,418 - 111,594,862 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411111,551,567 - 111,594,072NCBI
Celera11109,199,441 - 109,242,886 (+)NCBICelera
Cytogenetic Map11q23.1NCBI
HuRef11107,970,380 - 108,015,210 (+)NCBIHuRef
CHM1_111111,929,662 - 111,973,106 (+)NCBICHM1_1
T2T-CHM13v2.011112,185,841 - 112,229,285 (+)NCBIT2T-CHM13v2.0
Bco2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39950,444,387 - 50,466,513 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl950,444,387 - 50,466,481 (-)EnsemblGRCm39 Ensembl
GRCm38950,533,087 - 50,555,214 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl950,533,087 - 50,555,181 (-)EnsemblGRCm38mm10GRCm38
MGSCv37950,341,192 - 50,363,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36950,285,381 - 50,302,932 (-)NCBIMGSCv36mm8
Celera947,822,891 - 47,850,079 (-)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map927.74NCBI
Bco2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8859,778,571 - 59,803,597 (-)NCBIGRCr8
mRatBN7.2850,882,174 - 50,907,676 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl850,882,181 - 50,915,467 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx856,387,689 - 56,412,994 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0854,666,588 - 54,691,892 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0852,530,858 - 52,556,168 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0854,965,577 - 54,990,604 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl854,965,583 - 54,998,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0853,562,900 - 53,587,926 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4853,892,017 - 53,917,522 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1853,911,481 - 53,932,108 (-)NCBI
Celera850,430,781 - 50,455,782 (-)NCBICelera
Cytogenetic Map8q23NCBI
Bco2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541213,837,782 - 13,872,886 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541213,838,260 - 13,872,886 (+)NCBIChiLan1.0ChiLan1.0
BCO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1520,914,658 - 20,969,847 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl520,915,647 - 20,964,177 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha520,838,144 - 20,892,509 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0520,937,599 - 20,992,072 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl520,919,161 - 20,987,893 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1521,000,542 - 21,054,904 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0520,900,812 - 20,955,168 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0520,948,956 - 20,998,527 (-)NCBIUU_Cfam_GSD_1.0
Bco2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494794,411,396 - 94,443,419 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366122,262,066 - 2,294,255 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366122,262,115 - 2,294,287 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl939,872,645 - 39,917,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1939,864,136 - 39,916,491 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2944,716,295 - 44,767,961 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103248467
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11103,511,730 - 103,566,526 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1103,521,658 - 103,565,659 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604322,419,766 - 22,475,321 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bco2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247847,334,472 - 7,353,802 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247847,324,312 - 7,353,733 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003805445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008971507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034933672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055094831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063608782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008620260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000059801   ⟹   ENSPPAP00000036906
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11110,899,703 - 110,942,547 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000059804   ⟹   ENSPPAP00000036909
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11110,899,986 - 110,942,547 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000059816   ⟹   ENSPPAP00000036921
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11110,917,246 - 110,941,500 (+)Ensembl
RefSeq Acc Id: XM_055094829   ⟹   XP_054950804
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,924,681 - 112,963,647 (+)NCBI
NHGRI_mPanPan111114,015,156 - 114,063,152 (+)NCBI
RefSeq Acc Id: XM_055094831   ⟹   XP_054950806
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,798 - 112,962,813 (+)NCBI
NHGRI_mPanPan111114,015,153 - 114,057,322 (+)NCBI
RefSeq Acc Id: XM_063608775   ⟹   XP_063464845
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,799 - 112,971,307 (+)NCBI
RefSeq Acc Id: XM_063608776   ⟹   XP_063464846
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,798 - 112,968,643 (+)NCBI
RefSeq Acc Id: XM_063608777   ⟹   XP_063464847
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,797 - 112,962,820 (+)NCBI
RefSeq Acc Id: XM_063608778   ⟹   XP_063464848
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,421 - 112,962,807 (+)NCBI
RefSeq Acc Id: XM_063608779   ⟹   XP_063464849
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,418 - 112,962,428 (+)NCBI
RefSeq Acc Id: XM_063608780   ⟹   XP_063464850
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,805 - 112,963,647 (+)NCBI
RefSeq Acc Id: XM_063608781   ⟹   XP_063464851
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,935,059 - 112,971,307 (+)NCBI
RefSeq Acc Id: XM_063608782   ⟹   XP_063464852
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,921,008 - 112,963,647 (+)NCBI
RefSeq Acc Id: XR_008620260
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29112,920,417 - 112,962,729 (+)NCBI
NHGRI_mPanPan111114,015,150 - 114,057,316 (+)NCBI
Ensembl Acc Id: ENSPPAP00000036909   ⟸   ENSPPAT00000059804
Ensembl Acc Id: ENSPPAP00000036906   ⟸   ENSPPAT00000059801
Ensembl Acc Id: ENSPPAP00000036921   ⟸   ENSPPAT00000059816
RefSeq Acc Id: XP_054950806   ⟸   XM_055094831
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054950804   ⟸   XM_055094829
- Peptide Label: isoform X6
- UniProtKB: A0A2R9C516 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464849   ⟸   XM_063608779
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464848   ⟸   XM_063608778
- Peptide Label: isoform X3
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464847   ⟸   XM_063608777
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464846   ⟸   XM_063608776
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464845   ⟸   XM_063608775
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464850   ⟸   XM_063608780
- Peptide Label: isoform X5
- UniProtKB: A0A2R9C4N2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464852   ⟸   XM_063608782
- Peptide Label: isoform X6
- UniProtKB: A0A2R9C516 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063464851   ⟸   XM_063608781
- Peptide Label: isoform X6
- UniProtKB: A0A2R9C516 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041214 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059801.1 UniProtKB/TrEMBL
  ENSPPAT00000059804.1 UniProtKB/TrEMBL
  ENSPPAT00000059816.1 UniProtKB/TrEMBL
InterPro Carotenoid_Oase UniProtKB/TrEMBL
KEGG Report pps:100968503 UniProtKB/TrEMBL
NCBI Gene BCO2 ENTREZGENE
PANTHER BETA,BETA-CAROTENE 9',10'-OXYGENASE UniProtKB/TrEMBL
  PTHR10543 UniProtKB/TrEMBL
Pfam RPE65 UniProtKB/TrEMBL
UniProt A0A2R9C4N2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C4Q2_PANPA UniProtKB/TrEMBL
  A0A2R9C516 ENTREZGENE, UniProtKB/TrEMBL