PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase like 1) - Rat Genome Database

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Gene: PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase like 1) Pan paniscus
Analyze
Symbol: PIP5KL1
Name: phosphatidylinositol-4-phosphate 5-kinase like 1
RGD ID: 11709768
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-4-phosphate 5-kinase activity (inferred); ATP binding (inferred); kinase activity (inferred); INVOLVED IN negative regulation of cell migration (inferred); negative regulation of mitochondrial membrane potential (inferred); negative regulation of protein phosphorylation (inferred); ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 31A (ortholog); FOUND IN cell projection (inferred); cytosol (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphatidylinositol 4-phosphate 5-kinase-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,422,581 - 11,432,558 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,420,766 - 11,434,906 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,041,687 - 99,051,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,712,944 - 127,722,332 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,712,944 - 127,722,332 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PIP5KL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,422,581 - 11,432,558 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,420,766 - 11,434,906 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,041,687 - 99,051,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,712,944 - 127,722,332 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,712,944 - 127,722,332 (-)Ensemblpanpan1.1panPan2
PIP5KL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,920,881 - 127,930,777 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,920,881 - 127,930,785 (-)EnsemblGRCh38hg38GRCh38
GRCh379130,683,160 - 130,693,056 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,723,629 - 129,729,591 (-)NCBINCBI36Build 36hg18NCBI36
Build 349127,763,361 - 127,769,324NCBI
Celera9101,335,032 - 101,344,303 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,300,746 - 100,310,021 (-)NCBIHuRef
CHM1_19130,836,106 - 130,845,374 (-)NCBICHM1_1
T2T-CHM13v2.09140,128,656 - 140,138,557 (-)NCBIT2T-CHM13v2.0
Pip5kl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,465,238 - 32,473,799 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,464,809 - 32,473,794 (+)EnsemblGRCm39 Ensembl
GRCm38232,575,226 - 32,583,787 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,574,797 - 32,583,782 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,431,339 - 32,439,299 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,397,828 - 32,405,788 (+)NCBIMGSCv36mm8
Celera232,281,603 - 32,289,592 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Pip5kl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,258,141 - 36,266,902 (+)NCBIGRCr8
mRatBN7.2315,860,493 - 15,869,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,855,946 - 15,869,165 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0311,592,156 - 11,597,513 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,593,655 - 11,597,410 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,941,608 - 16,947,929 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera310,600,220 - 10,608,899 (+)NCBICelera
Cytogenetic Map3p11NCBI
Pip5kl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419745,344 - 753,819 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955419745,400 - 753,819 (+)NCBIChiLan1.0ChiLan1.0
PIP5KL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,490,881 - 55,499,755 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,490,942 - 55,498,891 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,684,983 - 54,693,829 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,412,941 - 56,421,788 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,413,002 - 56,420,828 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,172,948 - 55,181,794 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,487,663 - 55,496,508 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,578,889 - 55,587,737 (+)NCBIUU_Cfam_GSD_1.0
Pip5kl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,785,445 - 195,793,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,554,565 - 15,562,131 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,554,565 - 15,562,131 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIP5KL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,408,448 - 268,417,944 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,409,113 - 268,417,580 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,331,469 - 302,339,378 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIP5KL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,191,317 - 10,201,268 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,191,818 - 10,200,949 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660796,016,840 - 6,027,165 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pip5kl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,642,577 - 7,651,083 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,642,551 - 7,650,321 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000042063   ⟹   ENSPPAP00000019305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,712,944 - 127,722,332 (-)Ensembl
RefSeq Acc Id: XM_003822307   ⟹   XP_003822355
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,422,581 - 11,432,558 (+)NCBI
NHGRI_mPanPan1911,424,929 - 11,434,906 (+)NCBI
Mhudiblu_PPA_v0999,041,687 - 99,051,031 (-)NCBI
PanPan1.19127,712,944 - 127,722,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008975831   ⟹   XP_008974079
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,422,581 - 11,432,558 (+)NCBI
NHGRI_mPanPan1911,424,929 - 11,434,906 (+)NCBI
Mhudiblu_PPA_v0999,041,687 - 99,051,031 (-)NCBI
PanPan1.19127,712,944 - 127,722,332 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008975832   ⟹   XP_008974080
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,422,633 - 11,432,558 (+)NCBI
NHGRI_mPanPan1911,424,981 - 11,434,906 (+)NCBI
Mhudiblu_PPA_v0999,041,687 - 99,050,979 (-)NCBI
PanPan1.19127,712,944 - 127,722,316 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034929134   ⟹   XP_034785025
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,422,581 - 11,432,558 (+)NCBI
NHGRI_mPanPan1911,424,929 - 11,434,906 (+)NCBI
Mhudiblu_PPA_v0999,041,687 - 99,051,031 (-)NCBI
RefSeq Acc Id: XM_034929135   ⟹   XP_034785026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,422,627 - 11,432,558 (+)NCBI
NHGRI_mPanPan1911,424,975 - 11,434,906 (+)NCBI
Mhudiblu_PPA_v0999,041,687 - 99,050,985 (-)NCBI
RefSeq Acc Id: XP_008974079   ⟸   XM_008975831
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003822355   ⟸   XM_003822307
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AU62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008974080   ⟸   XM_008975832
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_034785025   ⟸   XM_034929134
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034785026   ⟸   XM_034929135
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000019305   ⟸   ENSPPAT00000042063
Protein Domains
PIPK


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032832 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042063.1 UniProtKB/TrEMBL
Gene3D-CATH 2-Layer Sandwich UniProtKB/TrEMBL
  3.30.800.10 UniProtKB/TrEMBL
InterPro PInositol-4-P-4/5-kinase_C_sf UniProtKB/TrEMBL
  PInositol-4-P-5-kinase UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_core UniProtKB/TrEMBL
  PInositol-4-P-5-kinase_N UniProtKB/TrEMBL
KEGG Report pps:100996122 UniProtKB/TrEMBL
NCBI Gene PIP5KL1 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE-LIKE PROTEIN 1 UniProtKB/TrEMBL
  PTHR23086 UniProtKB/TrEMBL
Pfam PIP5K UniProtKB/TrEMBL
PROSITE PIPK UniProtKB/TrEMBL
SMART PIPKc UniProtKB/TrEMBL
Superfamily-SCOP SAICAR synthase-like UniProtKB/TrEMBL
UniProt A0A2R9AU62 ENTREZGENE, UniProtKB/TrEMBL