CCDC65 (coiled-coil domain containing 65)

Gene: CCDC65 (coiled-coil domain containing 65) Pan paniscus

Analyze

Symbol:

CCDC65

Name:

coiled-coil domain containing 65

RGD ID:

11709695

Description:

INVOLVED IN axonemal dynein complex assembly (inferred); cilium assembly (inferred); cilium-dependent cell motility (inferred); ASSOCIATED WITH Cough (ortholog); genetic disease (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN axonemal dynein complex (inferred); axoneme (inferred); ciliary basal body (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 65; dynein regulatory complex subunit 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,263,470 - 45,279,339 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,260,231 - 45,276,283 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	39,829,171 - 39,845,221 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,708,937 - 40,723,750 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,697,723 - 40,723,750 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cough (ISO)

genetic disease (ISO)

primary ciliary dyskinesia (ISO)

primary ciliary dyskinesia 27 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axonemal dynein complex assembly (IEA)

cilium assembly (IEA)

cilium-dependent cell motility (IEA)

regulation of cilium movement (IEA)

Cellular Component

axonemal dynein complex (IEA)

axoneme (IEA)

ciliary basal body (IEA)

cytoplasm (IEA)

motile cilium (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

CCDC65
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	45,263,470 - 45,279,339 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	45,260,231 - 45,276,283 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	39,829,171 - 39,845,221 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	40,708,937 - 40,723,750 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	40,697,723 - 40,723,750 (-)	Ensembl	panpan1.1		panPan2

CCDC65
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	48,904,133 - 48,921,576 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	48,904,110 - 48,931,840 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	49,297,916 - 49,315,359 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	47,584,197 - 47,601,625 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	48,092,267 - 48,109,838 (+)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	46,329,756 - 46,347,363 (+)	NCBI		HuRef
CHM1_1	12	49,263,727 - 49,281,199 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	48,866,309 - 48,883,770 (+)	NCBI		T2T-CHM13v2.0

Ccdc65
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	98,606,075 - 98,621,221 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	98,606,088 - 98,621,217 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	98,708,194 - 98,723,340 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	98,708,207 - 98,723,336 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	98,538,658 - 98,553,767 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	98,536,261 - 98,551,370 (+)	NCBI		MGSCv36	mm8
Celera	15	100,856,708 - 100,871,723 (+)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	54.65	NCBI

Ccdc65
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	131,736,002 - 131,749,761 (+)	NCBI		GRCr8
mRatBN7.2	7	129,857,118 - 129,870,803 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	129,857,247 - 129,870,803 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	131,664,390 - 131,677,788 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	133,889,935 - 133,903,335 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	133,802,444 - 133,815,847 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	140,383,395 - 140,397,186 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	140,383,397 - 140,397,179 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	114,893,569 - 114,907,348 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	137,474,981 - 137,489,918 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	126,346,335 - 126,360,127 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

Ccdc65
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955500	7,733,045 - 7,747,327 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955500	7,733,054 - 7,744,135 (+)	NCBI	ChiLan1.0	ChiLan1.0

CCDC65
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	5,639,886 - 5,650,140 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	5,639,893 - 5,650,109 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	40,607,677 - 40,617,811 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	5,690,883 - 5,701,009 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	5,689,485 - 5,701,008 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	5,654,819 - 5,664,943 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	5,644,882 - 5,655,006 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	40,999,973 - 41,010,107 (+)	NCBI		UU_Cfam_GSD_1.0

Ccdc65
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	66,433,256 - 66,443,987 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	6,720,693 - 6,731,478 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	6,720,846 - 6,731,955 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC65
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	14,950,492 - 14,959,327 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	14,949,864 - 14,958,967 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	15,361,365 - 15,368,749 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC65
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	45,146,225 - 45,166,152 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	45,147,199 - 45,165,761 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	200,982,844 - 200,998,419 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc65
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	3,266,395 - 3,280,855 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	3,266,483 - 3,282,580 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008951149	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000064844 ⟹ ENSPPAP00000041916

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	40,697,723 - 40,723,527 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000064848 ⟹ ENSPPAP00000041920

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	40,708,937 - 40,723,750 (-)	Ensembl

RefSeq Acc Id:

XM_008951149 ⟹ XP_008949397

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	45,263,470 - 45,279,339 (-)	NCBI
NHGRI_mPanPan1	12	45,260,231 - 45,276,283 (-)	NCBI
Mhudiblu_PPA_v0	12	39,829,171 - 39,845,221 (-)	NCBI
PanPan1.1	12	40,708,937 - 40,723,750 (-)	NCBI

Sequence:

show sequence

TCCTCGTTGCTAGGAGACTAGACGCGTCTTACCGTGGGAGAGCTCAGCCTCACTGATAGCCGGG
GATCTCTCCTGTTCGAGGGCTGAGATCTCCGGTCCCACAACCGCCCACAACCAGGGGCACTTCT
GGAAGGCCCCTTTCTAGGGACATTTTTCTTCTAAGCTCTGTAACGCGGGCCGAGGCAGACCGAG
GCTTCTTTCCTGGATCCAATCCCCTGCCCCCATGCCTAAGAAAGAAAAAATGGCCAAGACGCCC
CTGTCCGATGAGGAGCAGCTGCTTCTGTTTCAGCAGAAGTTGCTGGCAGAGGAGGAGATGGCCA
AAAAGAAGGAGAGGCTCCTCAGCCAGTTCTTGAAGGACAAGCTGGCCAAGGAGGAACACAACAG
TGCTCTGAACCTTAATAAGATTAACACACAGTGGAGAACTGTCCTTCGGGAAGTCAAGACCAGA
GAACTTCATAAGGACATTGAGATCCTCAGCCAAACATTTGAACGAGTGGTGGACTGTAAGGACA
ATGTCATCAAGTCTTTAGCTAAAGACCTGTCCGAAGCCGAGGAGCAGTACGCCCGTGCCCTGCG
CAGCCACTTGCACAATGTTGACCAGCTCTTGGCCCTGCAGAGGCGCCGGCTCAGTCTCCTGGAG
GAAAGTTACAACATGGAGCTGGAAGCCCTAACCAAGGAGTTTGAGACAGAAAGGAAGACAATTA
TTGACCAACATGAGAAAGAGATTCACTATCTGCAAGATATCTTCATGGCCATGGAGCAGAACTA
TATAGATTCTGAGTATGAAAGCAAGCTGGAGTTCCAGAGCATGTGGAATGATCTCAAAAACATG
AATTTAGAAGAGAAGCACTTTCTAAGACTGCACCTGGAGAACATAGTAGAAGATCTGTGGAGAA
AGTTCCAGGATGTACTCAAGAATTACACTGATGCCACAGAGGATCGAAAGGCTGCCTTTGAGAC
CCTGCAGGTGAAGGATGAGAAGAGCTCCAAAGAGATTGAAGTACAGATGAAAAAAATACAGAAA
CTACAGGATGCCATAACTATTTCAAAAGGCAAGATCATGATACACAGCCGTGAGAGTGAAGATG
AGAACCGGTATATCCGTAATGACAAGGAATTGGTCCTGGTACAACTGCGAAAACTTAAGGCCCA
AAGGACTCAGGCCCGGGCAGCATCCCAGAAGAACTTAGTCAGACTCACCCTGGAAAGTAATGCC
ACCCTCAAGGCCCTGAGAAAGATTGTTGATAAGGGTGAAAAGATCCTTAAACTTGCTGAAATAT
GTAGGAAATTTGAAACCGAGGAAGAAAAAGTGCTGCCTTTTTATTCATCAGTATTGACTCCTAA
GGAGCAGGAGGGGATTCAGGAGAATAATCTAGAAGAGCTTACTGAGGAGCTCACCAAGGTGATG
GTGGACTACATAGGAATGGAGAATTTCTGGAAAAGGTACAACAAAGTGAAACTGGAGCAACTGA
GCCTCCAACATAGACGAGCCCAGCTGCTAGATATCAATGGGAAGCTGCGGGAGATGCTGAAGCA
GTACTTGGATGGCATCTCAGTGAGTGACGAAGTGCTGAGCCAGCTCAACCCACTCTTTATAGTC
AACTATCAAAGCAACTTACCCCAGCCCTTGTCCATACGTATAGCCCATCCAGGTGATAAACAAC
ATCCAACCACTTAAAATATAATTGAAGCAGCCCACATGATCTTCCACAACCTGTGATCTAAGGA
AAAAAATCTTTCAACTCCTAGAGATTTTTTTTTTTTTTGAGAAATGTAGGGATGTTGCTATTAA
AAATTTCCATGGAGTTTA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008949397	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000041916.1
	ENSPPAP00000041920
	ENSPPAP00000041920.1

RefSeq Acc Id:

XP_008949397 ⟸ XM_008951149

- UniProtKB:

A0A2R9CJ03 (UniProtKB/TrEMBL), A0A2R9CIW7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPKKEKMAKTPLSDEEQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQ
WRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYARALRSHLHNVDQLL
ALQRRRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLE
FQSMWNDLKNMNLEEKHFLRLHLENIVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSK
EIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQK
NLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQENNL
EELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDE
VLSQLNPLFIVNYQSNLPQPLSIRIAHPGDKQHPTT

hide sequence

RefSeq Acc Id:

ENSPPAP00000041920 ⟸ ENSPPAT00000064848

RefSeq Acc Id:

ENSPPAP00000041916 ⟸ ENSPPAT00000064844

Protein Domains

Dynein regulatory complex protein 1/2 N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000043558	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000064844.1	UniProtKB/TrEMBL
	ENSPPAT00000064848.1	UniProtKB/TrEMBL
InterPro	DRC1/2_N	UniProtKB/TrEMBL
	DRC1/DRC2	UniProtKB/TrEMBL
KEGG Report	pps:100992939	UniProtKB/TrEMBL
NCBI Gene	CCDC65	ENTREZGENE
PANTHER	DYNEIN REGULATORY COMPLEX SUBUNIT 2	UniProtKB/TrEMBL
	PTHR21625	UniProtKB/TrEMBL
Pfam	NYD-SP28	UniProtKB/TrEMBL
UniProt	A0A2R9CIW7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CJ03	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM