AK1 (adenylate kinase 1) - Rat Genome Database

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Gene: AK1 (adenylate kinase 1) Pan paniscus
Analyze
Symbol: AK1
Name: adenylate kinase 1
RGD ID: 11707628
Description: ENCODES a protein that exhibits adenylate kinase activity (ortholog); phosphotransferase activity, phosphate group as acceptor (ortholog); INVOLVED IN ADP biosynthetic process (ortholog); AMP metabolic process (ortholog); cerebellum development (ortholog); PARTICIPATES IN adefovir pharmacokinetics pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; ASSOCIATED WITH congenital disorder of glycosylation Iu (ortholog); congenital nonspherocytic hemolytic anemia (ortholog); Congenital Nonspherocytic Hemolytic Anemia 3 (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog); sarcomere (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate kinase isoenzyme 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,476,471 - 11,486,406 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,478,853 - 11,488,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,987,348 - 98,997,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,657,338 - 127,678,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,657,338 - 127,678,245 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,476,471 - 11,486,406 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,478,853 - 11,488,753 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0998,987,348 - 98,997,252 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,657,338 - 127,678,245 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,657,338 - 127,678,245 (-)Ensemblpanpan1.1panPan2
AK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389127,866,480 - 127,879,621 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9127,866,486 - 127,877,675 (-)EnsemblGRCh38hg38GRCh38
GRCh379130,628,759 - 130,641,900 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,668,580 - 129,679,843 (-)NCBINCBI36Build 36hg18NCBI36
Build 349127,708,222 - 127,719,495NCBI
Celera9101,279,601 - 101,290,850 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,246,223 - 100,257,472 (-)NCBIHuRef
CHM1_19130,780,691 - 130,791,941 (-)NCBICHM1_1
T2T-CHM13v2.09140,073,895 - 140,087,021 (-)NCBIT2T-CHM13v2.0
Ak1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,511,770 - 32,525,070 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,511,770 - 32,525,070 (+)EnsemblGRCm39 Ensembl
GRCm38232,621,758 - 32,635,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,621,758 - 32,635,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv37232,485,024 - 32,490,572 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,451,513 - 32,457,061 (+)NCBIMGSCv36mm8
Celera232,336,146 - 32,341,694 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Ak1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,310,113 - 36,320,760 (+)NCBIGRCr8
mRatBN7.2315,912,431 - 15,923,045 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,912,485 - 15,923,041 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,984,611 - 18,991,850 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,569,617 - 27,576,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,820,734 - 25,827,945 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,652,143 - 11,659,135 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0316,995,977 - 17,002,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4219,821,482 - 19,822,544 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1219,741,850 - 19,742,913 (+)NCBI
Celera310,656,923 - 10,664,139 (+)NCBICelera
Cytogenetic Map3p11NCBI
Ak1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419799,410 - 811,029 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955419799,415 - 807,138 (+)NCBIChiLan1.0ChiLan1.0
AK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,539,179 - 55,548,132 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,539,260 - 55,548,132 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,737,172 - 54,742,120 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,461,156 - 56,477,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl956,461,226 - 56,470,095 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1955,225,113 - 55,230,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,539,847 - 55,544,794 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,631,318 - 55,636,272 (+)NCBIUU_Cfam_GSD_1.0
Ak1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,739,140 - 195,748,925 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,507,498 - 15,517,469 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,507,663 - 15,517,401 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,355,033 - 268,365,598 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,355,032 - 268,365,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,278,352 - 302,287,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,251,793 - 10,261,635 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,256,054 - 10,261,465 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660795,960,893 - 5,972,066 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ak1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,684,109 - 7,693,405 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,684,098 - 7,693,051 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000045000   ⟹   ENSPPAP00000022193
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,657,338 - 127,664,389 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000045005   ⟹   ENSPPAP00000022198
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9127,658,684 - 127,678,245 (-)Ensembl
RefSeq Acc Id: XM_008975829   ⟹   XP_008974077
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,480,703 - 11,486,406 (+)NCBI
NHGRI_mPanPan1911,483,050 - 11,488,753 (+)NCBI
Mhudiblu_PPA_v0998,987,348 - 98,992,981 (-)NCBI
PanPan1.19127,657,338 - 127,664,389 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034929121   ⟹   XP_034785012
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,476,471 - 11,486,406 (+)NCBI
NHGRI_mPanPan1911,478,853 - 11,488,753 (+)NCBI
Mhudiblu_PPA_v0998,987,348 - 98,997,252 (-)NCBI
RefSeq Acc Id: XM_034929122   ⟹   XP_034785013
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21111,479,240 - 11,486,406 (+)NCBI
NHGRI_mPanPan1911,481,594 - 11,488,753 (+)NCBI
Mhudiblu_PPA_v0998,987,348 - 98,994,506 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008974077 (Get FASTA)   NCBI Sequence Viewer  
  XP_034785012 (Get FASTA)   NCBI Sequence Viewer  
  XP_034785013 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000022193
  ENSPPAP00000022193.1
  ENSPPAP00000022198.1
RefSeq Acc Id: XP_008974077   ⟸   XM_008975829
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AYN7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034785012   ⟸   XM_034929121
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AYP4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034785013   ⟸   XM_034929122
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AYP4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000022193   ⟸   ENSPPAT00000045000
Ensembl Acc Id: ENSPPAP00000022198   ⟸   ENSPPAT00000045005


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034277 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045000.1 UniProtKB/TrEMBL
  ENSPPAT00000045005.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Adenylat/UMP-CMP_kin UniProtKB/TrEMBL
  Adenylat_kinase_CS UniProtKB/TrEMBL
  AK1 UniProtKB/TrEMBL
  AK1/5 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report pps:100995434 UniProtKB/TrEMBL
NCBI Gene AK1 ENTREZGENE
PANTHER ADENYLATE KINASE ISOENZYME 1 UniProtKB/TrEMBL
  PTHR23359 UniProtKB/TrEMBL
Pfam ADK UniProtKB/TrEMBL
PRINTS ADENYLTKNASE UniProtKB/TrEMBL
PROSITE ADENYLATE_KINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9AYN7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AYP4 ENTREZGENE, UniProtKB/TrEMBL