FIGN (fidgetin, microtubule severing factor) - Rat Genome Database

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Gene: FIGN (fidgetin, microtubule severing factor) Pan paniscus
Analyze
Symbol: FIGN
Name: fidgetin, microtubule severing factor
RGD ID: 11707222
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); microtubule severing ATPase activity (inferred); INVOLVED IN locomotory behavior (ortholog); ASSOCIATED WITH autistic disorder (ortholog); Developmental Disease (ortholog); genetic disease (ortholog); FOUND IN nuclear matrix (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fidgetin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21366,279,486 - 66,407,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B66,289,122 - 66,600,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B168,259,440 - 168,387,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B168,258,315 - 168,385,768 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FIGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21366,279,486 - 66,407,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B66,289,122 - 66,600,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B168,259,440 - 168,387,036 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B168,258,315 - 168,385,768 (-)Ensemblpanpan1.1panPan2
FIGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382163,602,611 - 163,736,008 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2163,593,396 - 163,736,012 (-)EnsemblGRCh38hg38GRCh38
GRCh372164,459,121 - 164,592,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362164,172,364 - 164,300,759 (-)NCBINCBI36Build 36hg18NCBI36
Build 342164,291,556 - 164,293,651NCBI
Celera2158,074,075 - 158,202,502 (-)NCBICelera
Cytogenetic Map2q24.3NCBI
HuRef2156,346,627 - 156,474,914 (-)NCBIHuRef
CHM1_12164,470,008 - 164,598,433 (-)NCBICHM1_1
T2T-CHM13v2.02164,059,859 - 164,193,293 (-)NCBIT2T-CHM13v2.0
Fign
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39263,801,852 - 63,928,382 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl263,801,851 - 63,928,382 (-)EnsemblGRCm39 Ensembl
GRCm38263,971,508 - 64,098,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl263,971,507 - 64,098,038 (-)EnsemblGRCm38mm10GRCm38
MGSCv37263,815,418 - 63,936,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36263,778,670 - 63,898,827 (-)NCBIMGSCv36mm8
Celera265,662,900 - 65,783,578 (-)NCBICelera
Cytogenetic Map2C1.3NCBI
cM Map237.19NCBI
Fign
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8369,045,918 - 69,169,148 (-)NCBIGRCr8
mRatBN7.2348,637,510 - 48,760,772 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl348,642,496 - 48,760,787 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx351,971,883 - 52,089,709 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0360,555,393 - 60,673,211 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0358,345,891 - 58,463,522 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0349,992,250 - 50,120,601 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl349,992,397 - 50,120,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0356,637,401 - 56,764,164 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4346,006,895 - 46,130,212 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1345,903,265 - 46,026,612 (-)NCBI
Celera348,260,684 - 48,378,383 (-)NCBICelera
Cytogenetic Map3q21NCBI
Fign
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544910,271,014 - 10,393,859 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544910,271,125 - 10,400,631 (+)NCBIChiLan1.0ChiLan1.0
FIGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1368,914,023 - 9,045,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl368,920,224 - 8,922,977 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha369,049,767 - 9,190,855 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0369,038,947 - 9,180,410 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl369,039,164 - 9,180,469 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1369,048,565 - 9,189,817 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0369,106,216 - 9,231,397 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0369,220,027 - 9,345,231 (-)NCBIUU_Cfam_GSD_1.0
Fign
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303126,059,464 - 126,183,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646915,434,127 - 15,553,438 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646915,434,150 - 15,556,167 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FIGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1570,262,091 - 70,394,095 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11570,255,270 - 70,394,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21578,089,130 - 78,245,808 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FIGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11049,035,120 - 49,453,559 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1049,052,032 - 49,178,962 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040150,341,369 - 150,475,693 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fign
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247321,770,852 - 1,899,842 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247321,770,794 - 1,904,398 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000042804   ⟹   ENSPPAP00000020021
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B168,258,315 - 168,385,768 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042809   ⟹   ENSPPAP00000020026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2B168,261,372 - 168,267,930 (-)Ensembl
RefSeq Acc Id: XM_003820932   ⟹   XP_003820980
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21366,279,486 - 66,407,932 (-)NCBI
NHGRI_mPanPan12B66,289,122 - 66,422,907 (-)NCBI
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBI
PanPan1.12B168,259,440 - 168,387,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008974406   ⟹   XP_008972654
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21366,279,486 - 66,407,865 (-)NCBI
NHGRI_mPanPan12B66,289,122 - 66,422,806 (-)NCBI
Mhudiblu_PPA_v02B50,889,187 - 51,022,435 (-)NCBI
PanPan1.12B168,259,440 - 168,387,036 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003820980 (Get FASTA)   NCBI Sequence Viewer  
  XP_008972654 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000020021
  ENSPPAP00000020021.1
  ENSPPAP00000020026.1
Reference Protein Sequences
RefSeq Acc Id: XP_008972654   ⟸   XM_008974406
- Peptide Label: isoform X2
- UniProtKB: A0A2R9ARR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003820980   ⟸   XM_003820932
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ARQ6 (UniProtKB/TrEMBL),   A0A2R9ARR0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000020021   ⟸   ENSPPAT00000042804
RefSeq Acc Id: ENSPPAP00000020026   ⟸   ENSPPAT00000042809
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033218 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042804.1 UniProtKB/TrEMBL
  ENSPPAT00000042809.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  Fidgetin_ATPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
KEGG Report pps:100980317 UniProtKB/TrEMBL
NCBI Gene FIGN ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/TrEMBL
  FIDGETIN UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
PROSITE AAA UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9ARQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ARR0 ENTREZGENE, UniProtKB/TrEMBL