LOC100983381 (protein NPAT) - Rat Genome Database

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Gene: LOC100983381 (protein NPAT) Pan paniscus
Analyze
Symbol: LOC100983381 (Ensembl: NPAT)
Name: protein NPAT (Ensembl:nuclear protein, coactivator of histone transcription)
RGD ID: 11706591
Description: ENCODES a protein that exhibits transcription coactivator activity (inferred); transcription coregulator activity (inferred); transcription corepressor activity (inferred); INVOLVED IN in utero embryonic development (ortholog); ASSOCIATED WITH ataxia telangiectasia (ortholog); beta-ketothiolase deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); FOUND IN Cajal body (inferred); cytoplasm (inferred); Gemini of coiled bodies (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NPAT; nuclear protein, ataxia-telangiectasia locus
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29108,902,474 - 108,968,069 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111109,995,590 - 110,060,998 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011103,044,313 - 103,109,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111106,519,438 - 106,584,062 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11106,519,614 - 106,584,034 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100983381
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29108,902,474 - 108,968,069 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111109,995,590 - 110,060,998 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011103,044,313 - 103,109,809 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111106,519,438 - 106,584,062 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11106,519,614 - 106,584,034 (-)Ensemblpanpan1.1panPan2
NPAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811108,157,215 - 108,222,638 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11108,157,215 - 108,222,638 (-)EnsemblGRCh38hg38GRCh38
GRCh3711108,027,942 - 108,093,365 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611107,533,327 - 107,598,575 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411107,533,329 - 107,598,507NCBI
Celera11105,183,023 - 105,248,316 (-)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef11103,953,739 - 104,018,989 (-)NCBIHuRef
CHM1_111107,911,238 - 107,976,466 (-)NCBICHM1_1
T2T-CHM13v2.011108,164,767 - 108,230,180 (-)NCBIT2T-CHM13v2.0
Npat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39953,448,347 - 53,486,867 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl953,448,347 - 53,485,642 (+)EnsemblGRCm39 Ensembl
GRCm38953,536,889 - 53,575,627 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl953,537,047 - 53,574,342 (+)EnsemblGRCm38mm10GRCm38
MGSCv37953,345,152 - 53,383,732 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36953,299,442 - 53,342,125 (+)NCBIMGSCv36mm8
Celera950,796,827 - 50,835,424 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map929.12NCBI
Npat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8862,829,141 - 62,867,065 (+)NCBIGRCr8
mRatBN7.2853,932,993 - 53,970,875 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl853,932,993 - 53,970,875 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx859,458,359 - 59,496,260 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0857,737,381 - 57,775,286 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0855,601,620 - 55,639,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0858,120,179 - 58,158,052 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl858,120,179 - 58,158,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0856,703,321 - 56,740,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4856,997,121 - 57,034,888 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1857,015,748 - 57,052,272 (+)NCBI
Celera853,423,768 - 53,461,552 (+)NCBICelera
Cytogenetic Map8q24NCBI
Npat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541210,379,132 - 10,422,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541210,377,814 - 10,422,753 (-)NCBIChiLan1.0ChiLan1.0
NPAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1524,297,419 - 24,360,461 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl524,296,653 - 24,346,935 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha524,222,911 - 24,298,814 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0524,326,272 - 24,402,024 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl524,326,289 - 24,375,568 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1524,373,638 - 24,449,307 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0524,275,135 - 24,350,711 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0524,333,340 - 24,409,050 (+)NCBIUU_Cfam_GSD_1.0
LOC101974563
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494790,951,019 - 91,001,639 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936551534,846 - 587,604 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936551534,879 - 585,674 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NPAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl936,554,671 - 36,620,446 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1936,554,800 - 36,620,515 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2940,631,179 - 40,676,088 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103248402
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1199,589,818 - 99,653,031 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl199,591,416 - 99,652,922 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604326,305,961 - 26,370,260 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101710001
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247842,888,718 - 2,932,855 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247842,888,075 - 2,932,999 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000065484   ⟹   ENSPPAP00000042554
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11106,519,614 - 106,584,034 (-)Ensembl
RefSeq Acc Id: XM_003828343   ⟹   XP_003828391
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29108,902,474 - 108,968,057 (-)NCBI
NHGRI_mPanPan111109,995,590 - 110,060,998 (-)NCBI
Mhudiblu_PPA_v011103,044,313 - 103,109,809 (-)NCBI
PanPan1.111106,519,614 - 106,584,034 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008953739   ⟹   XP_008951987
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29108,902,474 - 108,968,069 (-)NCBI
NHGRI_mPanPan111109,995,590 - 110,060,943 (-)NCBI
Mhudiblu_PPA_v011103,044,313 - 103,109,809 (-)NCBI
PanPan1.111106,519,438 - 106,584,062 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055094795   ⟹   XP_054950770
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29108,902,474 - 108,968,031 (-)NCBI
NHGRI_mPanPan111109,995,590 - 110,060,948 (-)NCBI
RefSeq Acc Id: XM_055094796   ⟹   XP_054950771
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29108,902,474 - 108,967,827 (-)NCBI
NHGRI_mPanPan111109,995,590 - 110,060,744 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003828391 (Get FASTA)   NCBI Sequence Viewer  
  XP_008951987 (Get FASTA)   NCBI Sequence Viewer  
  XP_054950770 (Get FASTA)   NCBI Sequence Viewer  
  XP_054950771 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000042554.1
Reference Protein Sequences
RefSeq Acc Id: XP_008951987   ⟸   XM_008953739
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003828391   ⟸   XM_003828343
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CKQ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000042554   ⟸   ENSPPAT00000065484
RefSeq Acc Id: XP_054950770   ⟸   XM_055094795
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054950771   ⟸   XM_055094796
- Peptide Label: isoform X4
Protein Domains
Protein NPAT C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043838 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000065484.1 UniProtKB/TrEMBL
InterPro LisH UniProtKB/TrEMBL
  NPAT_C UniProtKB/TrEMBL
KEGG Report pps:100983381 UniProtKB/TrEMBL
NCBI Gene NPAT ENTREZGENE
PANTHER PROTEIN NPAT UniProtKB/TrEMBL
  PROTEIN NPAT UniProtKB/TrEMBL
Pfam NPAT_C UniProtKB/TrEMBL
PROSITE LISH UniProtKB/TrEMBL
SMART LisH UniProtKB/TrEMBL
UniProt A0A2R9CKQ4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 LOC100983381  protein NPAT  NPAT  nuclear protein, ataxia-telangiectasia locus  Symbol and/or name change 5135510 APPROVED