DNAAF11 (dynein axonemal assembly factor 11) - Rat Genome Database

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Gene: DNAAF11 (dynein axonemal assembly factor 11) Pan paniscus
Analyze
Symbol: DNAAF11
Name: dynein axonemal assembly factor 11
RGD ID: 11704690
Description: INVOLVED IN cerebrospinal fluid circulation (ortholog); cilium movement (ortholog); epithelial cilium movement involved in determination of left/right asymmetry (ortholog); ASSOCIATED WITH benign neonatal seizures (ortholog); Charcot-Marie-Tooth disease type 4 (ortholog); genetic disease (ortholog); FOUND IN apical cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine rich repeat containing 6; LRRC6; protein TILB homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27149,957,976 - 150,063,701 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18125,472,529 - 125,578,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08129,223,591 - 129,329,535 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18132,199,607 - 132,305,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8132,199,607 - 132,305,351 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DNAAF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27149,957,976 - 150,063,701 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18125,472,529 - 125,578,472 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08129,223,591 - 129,329,535 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18132,199,607 - 132,305,351 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8132,199,607 - 132,305,351 (-)Ensemblpanpan1.1panPan2
DNAAF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388132,570,416 - 132,702,913 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8132,570,416 - 132,675,592 (-)EnsemblGRCh38hg38GRCh38
GRCh378133,582,664 - 133,687,791 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368133,653,629 - 133,756,995 (-)NCBINCBI36Build 36hg18NCBI36
Build 348133,653,630 - 133,756,995NCBI
Celera8129,759,252 - 129,862,622 (-)NCBICelera
Cytogenetic Map8q24.22NCBI
HuRef8128,902,733 - 129,006,332 (-)NCBIHuRef
CHM1_18133,624,994 - 133,728,649 (-)NCBICHM1_1
T2T-CHM13v2.08133,693,703 - 133,826,388 (-)NCBIT2T-CHM13v2.0
Dnaaf11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391566,251,707 - 66,372,769 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1566,251,707 - 66,372,759 (-)EnsemblGRCm39 Ensembl
GRCm381566,379,858 - 66,500,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1566,379,858 - 66,500,910 (-)EnsemblGRCm38mm10GRCm38
MGSCv371566,211,420 - 66,332,472 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361566,209,527 - 66,330,510 (-)NCBIMGSCv36mm8
Celera1567,903,643 - 68,032,794 (-)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1529.22NCBI
Dnaaf11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87100,033,843 - 100,134,979 (-)NCBIGRCr8
mRatBN7.2798,141,525 - 98,245,906 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl798,144,763 - 98,245,837 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx799,899,274 - 100,006,426 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07102,100,939 - 102,208,084 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07102,020,292 - 102,127,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07107,130,402 - 107,231,507 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7107,130,402 - 107,223,047 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07107,073,711 - 107,174,936 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.07107,265,345 - 107,276,742 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47103,747,640 - 103,851,124 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera794,698,248 - 94,798,326 (-)NCBICelera
Cytogenetic Map7q33NCBI
Dnaaf11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554617,204,339 - 7,312,241 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554617,204,165 - 7,311,524 (-)NCBIChiLan1.0ChiLan1.0
DNAAF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11329,128,500 - 29,199,354 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1329,128,504 - 29,199,323 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1329,101,416 - 29,172,254 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01329,482,884 - 29,553,592 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1329,482,877 - 29,553,561 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11329,209,949 - 29,280,586 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01329,309,966 - 29,380,707 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01329,622,148 - 29,692,826 (-)NCBIUU_Cfam_GSD_1.0
Dnaaf11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053039,131,239 - 9,214,410 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647016,557,371 - 16,640,553 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647016,557,381 - 16,640,519 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAAF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl48,532,739 - 8,608,582 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.148,531,612 - 8,605,904 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.248,570,672 - 8,644,007 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DNAAF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18127,010,303 - 127,103,343 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8127,008,619 - 127,103,300 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603913,003,355 - 13,096,192 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnaaf11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473523,269,414 - 23,355,968 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473523,269,253 - 23,355,832 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036623   ⟹   ENSPPAP00000013948
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8132,199,607 - 132,291,222 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036635   ⟹   ENSPPAP00000013960
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8132,239,982 - 132,305,351 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036638   ⟹   ENSPPAP00000013963
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl8132,282,005 - 132,291,222 (-)Ensembl
RefSeq Acc Id: XM_003830093   ⟹   XP_003830141
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27149,957,976 - 150,063,701 (-)NCBI
NHGRI_mPanPan18125,472,529 - 125,578,472 (-)NCBI
Mhudiblu_PPA_v08129,223,591 - 129,329,535 (-)NCBI
PanPan1.18132,199,607 - 132,305,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008955466   ⟹   XP_008953714
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27149,959,984 - 150,063,701 (-)NCBI
NHGRI_mPanPan18125,474,537 - 125,578,472 (-)NCBI
Mhudiblu_PPA_v08129,225,522 - 129,329,535 (-)NCBI
PanPan1.18132,201,622 - 132,305,351 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034966617   ⟹   XP_034822508
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27149,995,687 - 150,063,701 (-)NCBI
NHGRI_mPanPan18125,510,235 - 125,578,472 (-)NCBI
Mhudiblu_PPA_v08129,262,190 - 129,329,535 (-)NCBI
RefSeq Acc Id: XM_057303090   ⟹   XP_057159073
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27149,957,976 - 150,063,688 (-)NCBI
NHGRI_mPanPan18125,472,529 - 125,578,472 (-)NCBI
RefSeq Acc Id: XM_063606908   ⟹   XP_063462978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27149,957,976 - 150,063,701 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003830141   ⟸   XM_003830093
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AEK2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008953714   ⟸   XM_008955466
- Peptide Label: isoform X3
- UniProtKB: A0A2R9A9L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034822508   ⟸   XM_034966617
- Peptide Label: isoform X4
- UniProtKB: A0A2R9A9L8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000013960   ⟸   ENSPPAT00000036635
RefSeq Acc Id: ENSPPAP00000013963   ⟸   ENSPPAT00000036638
RefSeq Acc Id: ENSPPAP00000013948   ⟸   ENSPPAT00000036623
RefSeq Acc Id: XP_057159073   ⟸   XM_057303090
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063462978   ⟸   XM_063606908
- Peptide Label: isoform X1
Protein Domains
CS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030101 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036623.1 UniProtKB/TrEMBL
  ENSPPAT00000036635.1 UniProtKB/TrEMBL
  ENSPPAT00000036638.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro CS_dom UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  U2A'_phosphoprotein32A_C UniProtKB/TrEMBL
NCBI Gene LRRC6 ENTREZGENE
PANTHER CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED UniProtKB/TrEMBL
  LEUCINE RICH REPEAT PROTEIN UniProtKB/TrEMBL
Pfam LRR_4 UniProtKB/TrEMBL
  LRR_9 UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  PS51203 UniProtKB/TrEMBL
SMART LRR_SD22 UniProtKB/TrEMBL
  LRRcap UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A2R9A9L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AEK2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AEL4_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-10 DNAAF11  dynein axonemal assembly factor 11  LRRC6  leucine rich repeat containing 6  Symbol and/or name change 5135510 APPROVED