SLC1A6 (solute carrier family 1 member 6) - Rat Genome Database

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Gene: SLC1A6 (solute carrier family 1 member 6) Pan paniscus
Analyze
Symbol: SLC1A6
Name: solute carrier family 1 member 6
RGD ID: 11703646
Description: ENCODES a protein that exhibits high-affinity L-glutamate transmembrane transporter activity (ortholog); monoatomic anion transmembrane transporter activity (ortholog); INVOLVED IN establishment of localization in cell (ortholog); L-glutamate transmembrane transport (ortholog); regulation of membrane potential (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); membrane protein complex (ortholog); parallel fiber to Purkinje cell synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: excitatory amino acid transporter 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,865,671 - 19,896,124 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,882,684 - 18,913,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,499,333 - 14,529,781 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,470,222 - 15,498,980 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,470,222 - 15,526,471 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC1A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,865,671 - 19,896,124 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,882,684 - 18,913,146 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,499,333 - 14,529,781 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,470,222 - 15,498,980 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,470,222 - 15,526,471 (-)Ensemblpanpan1.1panPan2
SLC1A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381914,950,033 - 15,010,643 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1914,950,033 - 15,022,990 (-)EnsemblGRCh38hg38GRCh38
GRCh371915,060,845 - 15,121,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,921,991 - 14,944,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 341914,921,990 - 14,944,730NCBI
Celera1914,956,703 - 14,979,425 (-)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,628,668 - 14,688,622 (-)NCBIHuRef
CHM1_11915,060,322 - 15,120,899 (-)NCBICHM1_1
T2T-CHM13v2.01915,074,841 - 15,135,544 (-)NCBIT2T-CHM13v2.0
Slc1a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,615,923 - 78,650,659 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,616,330 - 78,650,599 (+)EnsemblGRCm39 Ensembl
GRCm381078,780,086 - 78,814,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,780,496 - 78,814,765 (+)EnsemblGRCm38mm10GRCm38
MGSCv371078,243,241 - 78,277,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,183,631 - 78,217,894 (+)NCBIMGSCv36mm8
Celera1079,802,330 - 79,836,572 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Slc1a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,492,422 - 11,521,007 (-)NCBIGRCr8
mRatBN7.2710,841,836 - 10,870,424 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,841,837 - 10,870,449 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,661,837 - 13,690,559 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,539,283 - 15,568,001 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,417,320 - 13,445,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,730,101 - 13,758,170 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,730,253 - 13,751,271 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0713,893,841 - 13,921,839 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,393,284 - 12,419,893 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,393,284 - 12,419,880 (-)NCBI
Celera78,958,917 - 8,988,056 (-)NCBICelera
Cytogenetic Map7q11NCBI
Slc1a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554958,289,734 - 8,314,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554958,270,601 - 8,314,874 (+)NCBIChiLan1.0ChiLan1.0
SLC1A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,133,237 - 47,143,512 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,097,593 - 47,143,512 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,976,526 - 46,993,225 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,618,429 - 47,635,339 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,589,356 - 47,635,118 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,849,336 - 46,866,041 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,267,243 - 47,284,105 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,539,683 - 47,556,398 (+)NCBIUU_Cfam_GSD_1.0
Slc1a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,914,191 - 205,929,855 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,464,862 - 5,478,641 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,464,850 - 5,478,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC1A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,601,758 - 62,623,371 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,601,763 - 62,623,597 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2262,160,514 - 62,181,952 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC1A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,537,902 - 13,567,333 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,538,064 - 13,558,959 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660746,023,993 - 6,056,899 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc1a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,017,381 - 2,048,282 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,021,097 - 2,048,456 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000063309   ⟹   ENSPPAP00000040393
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,470,222 - 15,498,985 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000063329   ⟹   ENSPPAP00000040413
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,470,383 - 15,526,471 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000063338   ⟹   ENSPPAP00000040422
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,470,383 - 15,494,934 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000063342   ⟹   ENSPPAP00000040426
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,470,383 - 15,493,021 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000063344   ⟹   ENSPPAP00000040428
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,470,383 - 15,493,021 (-)Ensembl
RefSeq Acc Id: XM_008966119   ⟹   XP_008964367
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,865,671 - 19,889,895 (-)NCBI
NHGRI_mPanPan11918,882,684 - 18,906,913 (-)NCBI
Mhudiblu_PPA_v01914,499,333 - 14,523,445 (-)NCBI
PanPan1.11915,470,222 - 15,494,213 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034944476   ⟹   XP_034800367
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,865,671 - 19,895,328 (-)NCBI
NHGRI_mPanPan11918,882,684 - 18,912,350 (-)NCBI
Mhudiblu_PPA_v01914,499,333 - 14,528,985 (-)NCBI
RefSeq Acc Id: XM_034944477   ⟹   XP_034800368
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,865,671 - 19,895,183 (-)NCBI
NHGRI_mPanPan11918,882,684 - 18,912,205 (-)NCBI
Mhudiblu_PPA_v01914,499,333 - 14,528,840 (-)NCBI
RefSeq Acc Id: XM_034944478   ⟹   XP_034800369
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,865,671 - 19,895,393 (-)NCBI
NHGRI_mPanPan11918,882,684 - 18,912,419 (-)NCBI
Mhudiblu_PPA_v01914,499,333 - 14,529,051 (-)NCBI
RefSeq Acc Id: XM_055104181   ⟹   XP_054960156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,876,980 - 19,895,183 (-)NCBI
NHGRI_mPanPan11918,893,999 - 18,912,205 (-)NCBI
RefSeq Acc Id: XR_004667744
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,877,922 - 19,896,124 (-)NCBI
NHGRI_mPanPan11918,894,941 - 18,913,146 (-)NCBI
Mhudiblu_PPA_v01914,511,577 - 14,529,781 (-)NCBI
RefSeq Acc Id: XP_008964367   ⟸   XM_008966119
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CH68 (UniProtKB/TrEMBL),   A0A2R9CEP1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034800369   ⟸   XM_034944478
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CH68 (UniProtKB/TrEMBL),   A0A2R9CEP1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034800367   ⟸   XM_034944476
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CH68 (UniProtKB/TrEMBL),   A0A2R9CEP1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034800368   ⟸   XM_034944477
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CH68 (UniProtKB/TrEMBL),   A0A2R9CEP1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000040393   ⟸   ENSPPAT00000063309
RefSeq Acc Id: ENSPPAP00000040426   ⟸   ENSPPAT00000063342
RefSeq Acc Id: ENSPPAP00000040428   ⟸   ENSPPAT00000063344
RefSeq Acc Id: ENSPPAP00000040413   ⟸   ENSPPAT00000063329
RefSeq Acc Id: ENSPPAP00000040422   ⟸   ENSPPAT00000063338
RefSeq Acc Id: XP_054960156   ⟸   XM_055104181
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042819 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063309.1 UniProtKB/TrEMBL
  ENSPPAT00000063329.1 UniProtKB/TrEMBL
  ENSPPAT00000063338.1 UniProtKB/TrEMBL
  ENSPPAT00000063342.1 UniProtKB/TrEMBL
  ENSPPAT00000063344.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3860.10 UniProtKB/TrEMBL
InterPro Na-dicarboxylate_symporter UniProtKB/TrEMBL
  Na-dicarboxylate_symporter_CS UniProtKB/TrEMBL
  Na:dicarbo_symporter_sf UniProtKB/TrEMBL
KEGG Report pps:100975421 UniProtKB/TrEMBL
NCBI Gene SLC1A6 ENTREZGENE
PANTHER EXCITATORY AMINO ACID TRANSPORTER 4 UniProtKB/TrEMBL
  SODIUM/DICARBOXYLATE SYMPORTER-RELATED UniProtKB/TrEMBL
Pfam SDF UniProtKB/TrEMBL
PRINTS EDTRNSPORT UniProtKB/TrEMBL
PROSITE NA_DICARBOXYL_SYMP_1 UniProtKB/TrEMBL
  NA_DICARBOXYL_SYMP_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF118215 UniProtKB/TrEMBL
UniProt A0A2R9CEP1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CH68 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CHA5_PANPA UniProtKB/TrEMBL
  A0A2R9CHB9_PANPA UniProtKB/TrEMBL
  A0A2R9CPK2_PANPA UniProtKB/TrEMBL