METTL16 (methyltransferase 16, RNA N6-adenosine) - Rat Genome Database

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Gene: METTL16 (methyltransferase 16, RNA N6-adenosine) Pan paniscus
Analyze
Symbol: METTL16
Name: methyltransferase 16, RNA N6-adenosine (Ensembl:methyltransferase 16, N6-methyladenosine)
RGD ID: 11703191
Description: ENCODES a protein that exhibits methyltransferase activity (inferred); mRNA m(6)A methyltransferase activity (inferred); RNA binding (inferred); INVOLVED IN mRNA catabolic process (ortholog); mRNA destabilization (ortholog); mRNA processing (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: methyltransferase 16, N6-methyladenosine; methyltransferase like 16; methyltransferase-like protein 16; RNA N6-adenosine-methyltransferase METTL16; U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,996,782 - 10,091,416 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,964,193 - 12,058,939 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,407,331 - 2,500,418 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,292,498 - 2,505,933 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,292,498 - 2,376,277 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
METTL16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,996,782 - 10,091,416 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11711,964,193 - 12,058,939 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0172,407,331 - 2,500,418 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1172,292,498 - 2,505,933 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,292,498 - 2,376,277 (-)Ensemblpanpan1.1panPan2
METTL16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38172,415,715 - 2,511,888 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl172,405,562 - 2,511,891 (-)EnsemblGRCh38hg38GRCh38
GRCh37172,319,343 - 2,415,182 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36172,266,093 - 2,361,950 (-)NCBINCBI36Build 36hg18NCBI36
Celera172,335,440 - 2,431,686 (-)NCBICelera
Cytogenetic Map17p13.3NCBI
HuRef172,212,383 - 2,308,290 (-)NCBIHuRef
CHM1_1172,328,106 - 2,423,981 (-)NCBICHM1_1
T2T-CHM13v2.0172,304,395 - 2,400,696 (-)NCBIT2T-CHM13v2.0
Mettl16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,661,658 - 74,716,649 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,661,656 - 74,719,351 (+)EnsemblGRCm39 Ensembl
GRCm381174,770,815 - 74,826,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,770,830 - 74,828,525 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,584,365 - 74,632,194 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,587,058 - 74,634,887 (+)NCBIMGSCv36mm8
Celera1182,283,429 - 82,331,593 (+)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1145.76NCBI
Mettl16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81060,139,317 - 60,185,438 (+)NCBIGRCr8
mRatBN7.21059,640,915 - 59,697,291 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1059,640,972 - 59,687,061 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1064,287,246 - 64,333,554 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01063,792,831 - 63,839,139 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01059,255,200 - 59,301,516 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01061,626,595 - 61,682,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,626,597 - 61,672,136 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,348,436 - 61,394,456 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,087,541 - 62,134,061 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1058,672,069 - 58,727,828 (+)NCBICelera
Cytogenetic Map10q24NCBI
Mettl16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955481762,024 - 836,067 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955481762,030 - 836,299 (+)NCBIChiLan1.0ChiLan1.0
METTL16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1946,491,503 - 46,566,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl946,496,963 - 46,558,313 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha945,641,690 - 45,718,821 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0947,322,945 - 47,400,142 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl947,327,502 - 47,400,123 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1946,089,843 - 46,166,983 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0946,384,447 - 46,461,568 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0946,439,659 - 46,517,044 (-)NCBIUU_Cfam_GSD_1.0
Mettl16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560245,592,106 - 45,663,693 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365388,471,233 - 8,538,136 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365388,470,057 - 8,541,620 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
METTL16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1248,499,240 - 48,561,536 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11248,491,254 - 48,567,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21250,269,399 - 50,315,403 (-)NCBISscrofa10.2Sscrofa10.2susScr3
METTL16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1162,050,362 - 2,127,001 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl162,050,955 - 2,124,824 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605919,829,964 - 19,913,889 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mettl16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247865,070,311 - 5,134,669 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247865,063,127 - 5,134,387 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036209   ⟹   ENSPPAP00000013537
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl172,292,498 - 2,376,277 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036215   ⟹   ENSPPAP00000013543
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl172,296,263 - 2,376,276 (-)Ensembl
RefSeq Acc Id: XM_003816864   ⟹   XP_003816912
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,996,782 - 10,091,416 (-)NCBI
NHGRI_mPanPan11711,964,193 - 12,058,939 (-)NCBI
Mhudiblu_PPA_v0172,407,331 - 2,500,418 (-)NCBI
PanPan1.1172,292,498 - 2,505,933 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034941261   ⟹   XP_034797152
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2199,996,782 - 10,090,199 (-)NCBI
NHGRI_mPanPan11711,964,193 - 12,057,727 (-)NCBI
Mhudiblu_PPA_v0172,411,098 - 2,500,412 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003816912 (Get FASTA)   NCBI Sequence Viewer  
  XP_034797152 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000013537
  ENSPPAP00000013537.1
  ENSPPAP00000013543.1
Reference Protein Sequences
RefSeq Acc Id: XP_003816912   ⟸   XM_003816864
- Peptide Label: isoform X1
- UniProtKB: A0A2R9ADH3 (UniProtKB/TrEMBL),   A0A2R9ADG3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034797152   ⟸   XM_034941261
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000013543   ⟸   ENSPPAT00000036215
RefSeq Acc Id: ENSPPAP00000013537   ⟸   ENSPPAT00000036209


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029944 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036209.1 UniProtKB/TrEMBL
  ENSPPAT00000036215.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro METTL16/PsiM UniProtKB/TrEMBL
  METTL16/RlmF UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
KEGG Report pps:100985777 UniProtKB/TrEMBL
NCBI Gene METTL16 ENTREZGENE
PANTHER PTHR13393 UniProtKB/TrEMBL
  RNA N6-ADENOSINE-METHYLTRANSFERASE METTL16 UniProtKB/TrEMBL
Pfam Methyltransf_10 UniProtKB/TrEMBL
PIRSF Mtase_ZK1128_prd UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A2R9ADG3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ADH3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-30 METTL16  methyltransferase 16, RNA N6-adenosine  METTL16  methyltransferase 16, N6-methyladenosine  Symbol and/or name change 5135510 APPROVED
2021-05-25 METTL16  methyltransferase 16, N6-methyladenosine  METTL16  methyltransferase like 16  Symbol and/or name change 5135510 APPROVED