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Gene: CDC73 (cell division cycle 73) Pan paniscus

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Symbol:

CDC73

Name:

cell division cycle 73

RGD ID:

11702817

Description:

ENCODES a protein that exhibits RNA polymerase II complex binding (inferred); INVOLVED IN cellular response to lipopolysaccharide (inferred); endodermal cell fate commitment (inferred); mRNA 3'-end processing (inferred); PARTICIPATES IN RNA polymerase I transcription pathway; RNA polymerase II transcription elongation pathway; ASSOCIATED WITH breast cancer (ortholog); Breast Cancer, Familial (ortholog); colorectal cancer (ortholog); FOUND IN Cdc73/Paf1 complex (inferred); cytosol (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; parafibromin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	56,534,616 - 56,670,750 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	56,190,589 - 56,334,645 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	168,581,730 - 168,710,915 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	172,875,365 - 173,004,942 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	172,875,365 - 173,004,934 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast cancer (ISO)

Breast Cancer, Familial (ISO)

colorectal cancer (ISO)

Familial Cystic Parathyroid Adenomatosis (ISO)

gastric adenocarcinoma (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

head and neck squamous cell carcinoma (ISO)

Hereditary Neoplastic Syndromes (ISO)

hyperparathyroidism (ISO)

Hyperparathyroidism 1 (ISO)

Hyperparathyroidism 2 (ISO)

laryngeal squamous cell carcinoma (ISO)

lung adenocarcinoma (ISO)

lung cancer (ISO)

multiple endocrine neoplasia type 1 (ISO)

oral squamous cell carcinoma (ISO)

ossifying fibroma (ISO)

ovarian cancer (ISO)

parathyroid adenoma (ISO)

Parathyroid Cancer (ISO)

parathyroid carcinoma (ISO)

Parathyroid Neoplasms (ISO)

stomach cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to lipopolysaccharide (IEA)

endodermal cell fate commitment (IEA)

mRNA 3'-end processing (IEA)

negative regulation of apoptotic process (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of epithelial cell proliferation (IEA)

negative regulation of fibroblast proliferation (IEA)

negative regulation of G1/S transition of mitotic cell cycle (IEA)

negative regulation of myeloid cell differentiation (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

positive regulation of cell cycle G1/S phase transition (IEA)

positive regulation of mRNA 3'-end processing (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

positive regulation of transcription elongation by RNA polymerase II (IEA)

positive regulation of Wnt signaling pathway (IEA)

protein destabilization (IEA)

regulation of cell growth (IEA)

regulation of transcription by RNA polymerase II (IEA)

stem cell population maintenance (IEA)

transcription elongation by RNA polymerase II (IEA)

Cellular Component

Cdc73/Paf1 complex (IEA)

cytosol (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

protein binding (ISO)

RNA polymerase II complex binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase I transcription pathway (ISO)

RNA polymerase II transcription elongation pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

CDC73
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	56,534,616 - 56,670,750 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	56,190,589 - 56,334,645 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	168,581,730 - 168,710,915 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	172,875,365 - 173,004,942 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	172,875,365 - 173,004,934 (+)	Ensembl	panpan1.1		panPan2

CDC73
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	193,122,031 - 193,254,815 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	193,121,983 - 193,254,815 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	193,091,161 - 193,223,945 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	191,357,784 - 191,487,679 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	189,822,817 - 189,952,713	NCBI
Celera	1	166,200,694 - 166,333,560 (+)	NCBI		Celera
Cytogenetic Map	1	q31.2	NCBI
HuRef	1	164,326,911 - 164,459,852 (+)	NCBI		HuRef
CHM1_1	1	194,512,977 - 194,645,669 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	192,469,240 - 192,602,060 (+)	NCBI		T2T-CHM13v2.0

Cdc73
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	143,479,014 - 143,578,631 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	143,474,538 - 143,578,631 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	143,603,276 - 143,702,893 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	143,598,800 - 143,702,893 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	145,454,629 - 145,549,814 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	145,369,717 - 145,464,902 (-)	NCBI		MGSCv36	mm8
Celera	1	146,186,403 - 146,281,769 (-)	NCBI		Celera
Cytogenetic Map	1	F	NCBI
cM Map	1	62.52	NCBI

Cdc73
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	57,897,924 - 58,000,031 (-)	NCBI		GRCr8
mRatBN7.2	13	55,357,226 - 55,449,690 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	55,357,226 - 55,449,656 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	57,920,582 - 58,012,922 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	59,192,881 - 59,285,299 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	56,477,724 - 56,570,082 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	60,403,771 - 60,496,511 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	60,403,771 - 60,496,511 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	65,392,579 - 65,485,175 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	57,441,674 - 57,534,385 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	57,455,753 - 57,548,465 (-)	NCBI
Celera	13	55,444,707 - 55,537,113 (-)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

Cdc73
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	30,533,060 - 30,665,812 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	30,533,919 - 30,665,812 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDC73
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	5,826,209 - 5,937,930 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	5,805,916 - 5,938,111 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	5,923,156 - 6,034,975 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	5,842,156 - 5,954,484 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	5,841,856 - 5,954,492 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	5,841,710 - 5,953,973 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	6,206,980 - 6,319,388 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	6,435,831 - 6,547,946 (-)	NCBI		UU_Cfam_GSD_1.0

Cdc73
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	80,662,470 - 80,779,375 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936638	1,365,648 - 1,483,277 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936638	1,365,457 - 1,482,497 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDC73
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	575,075 - 667,432 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	575,075 - 667,618 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	2,279,054 - 2,305,137 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDC73
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	36,167,482 - 36,302,918 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	36,170,134 - 36,302,812 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	37,127,006 - 37,251,142 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdc73
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624814	299,444 - 460,391 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624814	298,015 - 460,314 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003820601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000045626 ⟹ ENSPPAP00000022812

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	172,875,365 - 173,004,934 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045633 ⟹ ENSPPAP00000022819

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	172,875,761 - 173,001,755 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000045638 ⟹ ENSPPAP00000022825

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	172,875,761 - 173,001,755 (+)	Ensembl

RefSeq Acc Id:

XM_003820601 ⟹ XP_003820649

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	56,534,616 - 56,670,750 (-)	NCBI
NHGRI_mPanPan1	1	56,190,589 - 56,334,645 (-)	NCBI
Mhudiblu_PPA_v0	1	168,581,730 - 168,710,915 (+)	NCBI
PanPan1.1	1	172,875,365 - 173,004,942 (+)	NCBI

Sequence:

show sequence

TCCCCGTACGTGCGCCGTACGTGGGCGCGGTGCCCCAGCGCTCAGCGTTTCAGCCAGTGAGTGG
GCTCCGTGCCCAGCTGAAGTCTGGGAGGGGCACTTTTCCAGGCGGTCGCGGCTCCCCCTGGCGG
CGGATGTGCCTCGCTGGAGGGGCGCAGTCAGGCGTTCTCCGCGGGCAGCCGGCGGCGGGGCCTT
GCCTTACAGCGCGGGGTCCTCGGCGGCCTGGGTGGCTACTGCCCCTGCTGCTGTCGTAGGCGAG
GACGGCTGTTAGTGCTGCTGCTGTTGGTTCGTCGCGGCGGCGAAGGAGGAGGAGGAAGAGGGCG
AGGCGACAAGAGAAGAAGGAGGCAGGCGCGGCGGCAGCGGCGGCGCCCCGGGCCGGCGGAGGCG
AGGGGGTGGAAGATGGCGGACGTGCTTAGCGTCCTGCGACAGTACAACATCCAGAAGAAGGAGA
TTGTGGTGAAGGGAGACGAAGTGATCTTCGGGGAGTTCTCCTGGCCCAAGAATGTGAAGACAAA
CTATGTTGTTTGGGGGACTGGAAAGGAAGGCCAACCCAGAGAGTACTACACATTGGATTCCATT
TTATTTCTACTTAATAATGTGCACCTTTCTCATCCTGTTTATGTCCGACGTGCAGCTACTGAAA
ATATTCCTGTCGTTAGAAGACCTGATCGAAAAGATCTACTTGGATATCTCAATGGTGAAGCGTC
AACATCGGCAAGTATAGACAGAAGCGCTCCCTTAGAAATAGGTCTTCAGCGATCTACTCAAGTC
AAACGAGCTGCAGATGAAGTTTTAGCAGAAGCAAAGAAACCAAGAATTGAGGATGAAGAGTGTG
TGCGCCTTGATAAAGAGAGATTGGCTGCCCGTTTGGAGGGTCACAAAGAAGGGATTGTACAGAC
TGAACAGATTAGGTCTTTGTCTGAAGCTATGTCAGTGGAAAAAATTGCTGCAATCAAAGCCAAA
ATTATGGCTAAGAAAAGATCTACTATCAAGACTGATCTAGATGATGACATAACTGCCCTTAAAC
AGAGGAGTTTTGTGGATGCTGAGGTAGATGTGACCCGAGATATTGTCAGCAGAGAGAGAGTATG
GAGGACACGAACAACTATCTTACAAAGCACAGGAAAGAATTTTTCCAAGAACATTTTTGCAATT
CTTCAATCTGTAAAAGCCAGAGAAGAAGGGCGTGCACCTGAACAGCGACCTGCCCCAAATGCAG
CACCTGTGGATCCCACTTTGCGCACCAAACAGCCTATCCCAGCTGCCTATAACAGATACGATCA
GGAAAGATTCAAAGGAAAAGAAGAAACGGAAGGCTTCAAAATTGACACTATGGGAACCTACCAT
GGTATGACACTGAAATCTGTAACGGAGGGTGCATCTGCCCGGAAGACTCAGACTCCTGCAGCCC
AGCCAGTACCAAGACCAGTTTCTCAAGCAAGACCTCCCCCAAATCAGAAGAAAGGATCTCGAAC
ACCCATTATCATAATTCCTGCAGCTACCACCTCTTTAATAACCATGCTTAATGCAAAAGACCTT
CTACAGGACCTGAAATTTGTCCCATCAGATGAAAAGAAGAAACAAGGTTGTCAACGAGAAAATG
AAACTCTAATACAAAGAAGGAAAGACCAGATGCAACCAGGGGGCACTGCAATTAGTGTTACAGT
ACCTTACAGAGTAGTAGACCAGCCCCTTAAACTTATGCCTCAAGACTGGGACCGCGTTGTAGCC
GTTTTTGTGCAGGGTCCTGCATGGCAGTTCAAAGGTTGGCCATGGCTTTTGCCTGATGGATCAC
CAGTTGATATATTTGCTAAAATTAAAGCCTTCCATCTGAAGTATGATGAAGTTCGTCTGGATCC
AAATGTTCAGAAATGGGATGTAACAGTATTAGAACTCAGCTATCACAAACGTCATTTGGATAGA
CCAGTGTTCTTACGGTTTTGGGAAACATTGGACAGGTACATGGTAAAGCATAAATCCCACTTGA
GATTCTGAATTATTTGGCTCCTCCATTTCTGGAAATTGAGACTCAAGCTTTATGAATTTATCAA
GAACTTAAAAATGAAGAAGGTCACAGATTGATCTTTTATAAGACCTTATTTGATGCTTTGTGCT
TCAAGGAGATGATGCCTGTCATCCATATAAGCAAACTTTTTGGCTTACAACTATTTTTTTAATA
TTAGCCTTCTAGTCTGTAATGGAAATTGTATATTTTGATAGAAGTTTTTTCTCCATTGGTTAAA
TTAGCATTACTTAAAATTTGTTTCTTTAGAAAATAAATGCAGGTTATAAATGTGTGTATATTTA
GAGATTATAAGGCTCTCTGAGCCATCTTCTGATTTTTCATTGCTCTATAATTCTTTTTACTGAA
AATACTATGTTATGAATGGTATTAAATTTTAGTCTCTGGAACATCCAAAACCAAGCAAAGGGAT
GTGACTATTTTGAATGAATCAGAATGTCAACTTGTATGTACACTATATCTACACTTACTCATTA
TTTAAAAAGAATAATGAAAAATCTAGATCAATTCTTCAATTTGATTCAACTGTTCAGCCTTTTC
AAGATTTCTTTATTTACAAATGATTACATTTAAATGAATGTACATTCTTCTCACTGACTTTGGT
GATTTTGAAACCTAGAATGATGTGTTTCTATCTGTAATATCTTTCCATTTGAAAAAAATCTCAA
AACACAGATTAAAACCACAATAGGCTGTAGTATTTTTTATTTTGGGAGCCAGAGTATGATTTGG
GGGAAGAATATGTATCAGCCCTATTGCAGTATAACTTTAAGCTCCTTTTCTCTTTAGTCCACTT
TTGATTCTAATTTTTATGGTATAGGATTTTGAATCTTCTATTTTAGGCTTGTCAGTCTTGGAGT
TCTTATCTTCCATTATCCCTAAATATTGATAAACTCCCAGGCACCAAAGAAAACATTTGCTTAA
TTGTCTGAAAAGAAACAAGAGAAAAACACTGGTATTTTTATGTCTGTATTCAATATGGTATAAA
ATATAAAAACTATATTTTAACTTAGTGAAATATTTTACTATTTCTCTACTTCAGACAAAATGTT
GCATCCAAGGTACATCAAGTGACCATTTGCCTTGAACCTTGATTTCACTTTGTTTTTTTTTTCC
TTAAAGGCAACTAGGAAGCTTTACTTTCCTAAAGTGTTTTTGCCATTGGAATTTTTGCTGATCA
CAGTCTTATGTCATTTTTTTCTCTGTTTTTATTCCTAGCAATTTTCTCCTAGGTTAACATATTT
TTGGTGAACGTTTAGGCCTTCCATAGGTATTAAGCTGACATTATCTAGCTTCTTAATGAAATTT
AACACTGTCACAAAAATGAGAAGTTATTATTTTTTAAGTGATCACATAGTTCATACCACTAGTA
ACTAGAAAAGATATTTATTCACATGATATTTACAAGGCTCTTCAGAAGGGAACAGTCAGCATTT
TAAATTACTAGATTTTAGCATACTTACAAGGTTTGAACAGATTCTACCCCTATTTTCCTCCCTT
TTTAGGTCTGTCTTCTTTCCTTAAAGATAAAAGAAAACTCAAATTTGTTTACATTAGGCTTTCT
TAGCATATAAATATATTTCCAAAATAAATTACATGTTGTGTAAACTTTCTCCATGATGAAATAG
TCAAGGACCAGAATCTGTAATATTTTTATGTAAGATTACTTGTCAAGACTACTACAAATCAATA
TGAACTACCTTCCCATAAAGATTTTTGGTATTTGTACTTATTTATGAACTTTACTTGAGACAGA
ATATGGTTAAAATTAGGAACATCTACTTTGAATGAGGTTTATTTTTCTATTTTGAATTTGCCTT
ATCTATATTCAAAGGCTTATGGAAATACTGTAAAGGAACATTAGGAAAAGGACAAATATGCTAT
AACCATCTATCTTAAAATCAGACCCTTAGTATAAGCACCTCTTTTTCTTTTTCTCTTTGCCAAT
TTAGTCTCTTATTTAGGTCCATGTAATTAATTTCATTCCATTATTTTTTAGCTGTTTATTCTAA
AAAACAAAAAATTTCAGCCACTCCCATTTATTCTCCCATGACATGGTCCTATATAGCAGTACTT
AACACAGTGCCTTGCACATAGTAGGCATTCAGTAAATACTTACATGCATGAATGAATAATGTAT
TTTCAGTGTAACAAATTTATTATAAAAGTGTAGTTTGACTCTTCTTGGTCTTGGAGTTTGAGAG
TACAGAATTACAGGGAATGAAGAGAGGTATAAGTAGATATTTTAATGGAAATGAAGTATAAATT
AATAACTTGACTTACCCCTCCATAAGTTACTGCTAACTGGAGATACCCTTGTATGCCCAACCTG
TAAAGGAAAAAGTTCTATTTCTATACTTATAGGACATTCTTCTCAGTCAAGGAACAGTAAGAAA
TATGTAGGTTTCAATCAGTTGCTCTCAACCCTGCTGCATTTTAGAATCATTTGGAGAGTTTTAA
AAAATATCCATGCCTGAATCTTGATTCCCATTTTCATGTAATTTGAGACAAGACCTGGTCATCA
GTATTTTTTTAAAGTTCTCCAGGTAATTTGAATGTGCAGGAAGGATTCAGAATCACTGGTTTAA
TTTGTTATTGAAAACAGTACCAGTATTAAATGTGTTTCCTCTTCCTTCTTTTCTGTATGTATGT
GTGGTTTTTGATTTTTTGTTGTTGTTGTTGTTTTGTGGCCACCCTTTGCACTAGACCATCCCTG
TTATTGGTGGTATTGGCCTATATTCCCATTGACAAATGCAATTTTTAATTATTTATTTAATATA
GGAGTATTTTACTGTTTAATATTTAAACAATGTTTAATGTATTTCATTATTAACTAGTATTATA
GTTTGTTTTTTTCCCATGTCTCCATAACTTTTACTAACATTTGTTTTTAGCAGCACAACAGTAA
TCCATATAGAAACAACTAATTCATAATGAGGAAAATCTCATAATTTTTAAGGCAGAAAGAAGTA
TTAATTTTTGATCTGCCATGTAGAATGAGACAAATACAGTTTGCTTATGAAAGGAAAGTGGCAT
ACTTTTAAATTGGTCTACACAGAAAAGTAAAACTAAACTATTCATTTAAATAAGATTCATTATC
TAATAAATATTGAGGGAATATTTTTCCTAAATAAAAATTTTTCTGACTGCTAACAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003820649	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000022812.1
	ENSPPAP00000022819.1
	ENSPPAP00000022825.1

RefSeq Acc Id:

XP_003820649 ⟸ XM_003820601

- UniProtKB:

A0A2R9B3T2 (UniProtKB/TrEMBL), A0A2R9AZR6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADVLSVLRQYNIQKKEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQPREYYTLDSILFLL
NNVHLSHPVYVRRAATENIPVVRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQRSTQVKRAA
DEVLAEAKKPRIEDEECVRLDKERLAARLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIMAK
KRSTIKTDLDDDITALKQRSFVDAEVDVTRDIVSRERVWRTRTTILQSTGKNFSKNIFAILQSV
KAREEGRAPEQRPAPNAAPVDPTLRTKQPIPAAYNRYDQERFKGKEETEGFKIDTMGTYHGMTL
KSVTEGASARKTQTPAAQPVPRPVSQARPPPNQKKGSRTPIIIIPAATTSLITMLNAKDLLQDL
KFVPSDEKKKQGCQRENETLIQRRKDQMQPGGTAISVTVPYRVVDQPLKLMPQDWDRVVAVFVQ
GPAWQFKGWPWLLPDGSPVDIFAKIKAFHLKYDEVRLDPNVQKWDVTVLELSYHKRHLDRPVFL
RFWETLDRYMVKHKSHLRF

hide sequence

Ensembl Acc Id:

ENSPPAP00000022812 ⟸ ENSPPAT00000045626

Ensembl Acc Id:

ENSPPAP00000022819 ⟸ ENSPPAT00000045633

Ensembl Acc Id:

ENSPPAP00000022825 ⟸ ENSPPAT00000045638

Protein Domains

Cell division control protein 73 C-terminal Paf1 complex subunit Cdc73 N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034455	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000045626.1	UniProtKB/TrEMBL
	ENSPPAT00000045633.1	UniProtKB/TrEMBL
	ENSPPAT00000045638.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.11990	UniProtKB/TrEMBL
InterPro	Cdc73/Parafibromin	UniProtKB/TrEMBL
	CDC73_C	UniProtKB/TrEMBL
	CDC73_C_sf	UniProtKB/TrEMBL
	Cdc73_N	UniProtKB/TrEMBL
KEGG Report	pps:100969187	UniProtKB/TrEMBL
NCBI Gene	CDC73	ENTREZGENE
PANTHER	PARAFIBROMIN	UniProtKB/TrEMBL
	PTHR12466	UniProtKB/TrEMBL
Pfam	CDC73_C	UniProtKB/TrEMBL
	CDC73_N	UniProtKB/TrEMBL
UniProt	A0A2R9AZR6	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AZZ7_PANPA	UniProtKB/TrEMBL
	A0A2R9B3T2	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations