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Gene: MED25 (mediator complex subunit 25) Pan paniscus

Analyze

Symbol:

MED25

Name:

mediator complex subunit 25

RGD ID:

11700463

Description:

ENCODES a protein that exhibits nuclear retinoic acid receptor binding (inferred); nuclear retinoid X receptor binding (inferred); transcription coactivator binding (inferred); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription pathway; ASSOCIATED WITH autistic disorder (ortholog); Basel-Vanagaite-Smirin-Yosef syndrome (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

mediator of RNA polymerase II transcription subunit 25

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,933,021 - 55,955,983 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,853,775 - 57,876,771 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,831,190 - 46,853,367 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,747,445 - 55,765,978 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Basel-Vanagaite-Smirin-Yosef syndrome (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

Charcot-Marie-Tooth disease type 2B2 (ISO)

developmental and epileptic encephalopathy 12 (ISO)

Failure to Thrive (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

polyneuropathy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of fibroblast proliferation (IEA)

negative regulation of transcription by RNA polymerase II (IEA)

positive regulation of mediator complex assembly (IEA)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

transcription by RNA polymerase II (ISO)

Cellular Component

core mediator complex (IEA)

mediator complex (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO)

transcription regulator complex (IEA)

Molecular Function

nuclear retinoic acid receptor binding (IEA)

nuclear retinoid X receptor binding (IEA)

protein binding (ISO)

transcription coactivator binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase II transcription pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

MED25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,933,021 - 55,955,983 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,853,775 - 57,876,771 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,831,190 - 46,853,367 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,747,445 - 55,765,978 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl	panpan1.1		panPan2

MED25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,818,289 - 49,840,384 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,818,282 - 49,840,383 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	50,321,546 - 50,343,641 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	55,013,358 - 55,032,049 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	55,013,357 - 55,032,049	NCBI
Celera	19	47,190,990 - 47,209,687 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,697,846 - 46,716,581 (+)	NCBI		HuRef
CHM1_1	19	50,323,376 - 50,342,077 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,817,584 - 52,840,522 (+)	NCBI		T2T-CHM13v2.0

Med25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,526,189 - 44,544,771 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,526,189 - 44,542,136 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	44,876,765 - 44,892,705 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	44,876,765 - 44,892,712 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,134,756 - 52,147,736 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	44,747,428 - 44,760,409 (-)	NCBI		MGSCv36	mm8
Celera	7	40,329,552 - 40,342,567 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.95	NCBI

Med25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,496,447 - 104,513,061 (-)	NCBI		GRCr8
mRatBN7.2	1	95,359,961 - 95,375,827 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,360,284 - 95,375,877 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	100,748,078 - 100,760,955 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,220,743 - 109,233,620 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,511,152 - 102,524,029 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	100,872,240 - 100,887,864 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,874,976 - 100,887,853 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	101,936,861 - 101,952,758 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,351,526 - 95,364,403 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	95,429,640 - 95,442,595 (-)	NCBI
Celera	1	89,624,421 - 89,637,298 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Med25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,084,182 - 1,103,143 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,085,033 - 1,102,501 (-)	NCBI	ChiLan1.0	ChiLan1.0

MED25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,723,737 - 106,740,077 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,727,141 - 106,740,032 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,306,605 - 106,323,010 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,244,636 - 107,261,039 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,244,582 - 107,261,159 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,920,147 - 106,933,101 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,558,669 - 106,575,105 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,399,164 - 107,415,567 (-)	NCBI		UU_Cfam_GSD_1.0

Med25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,991,828 - 22,012,964 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,609,451 - 3,628,337 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,610,004 - 3,629,850 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MED25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,834,316 - 54,852,821 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,834,303 - 54,849,539 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	50,563,412 - 50,581,933 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MED25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,979,616 - 42,994,901 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,979,674 - 42,994,865 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,954,325 - 22,971,979 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Med25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,484,359 - 4,503,863 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,483,599 - 4,503,937 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008966986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034945441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055103350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055103352	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055103353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063600517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063600518	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000020	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000032659 ⟹ ENSPPAP00000010012

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032661 ⟹ ENSPPAP00000010014

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032668 ⟹ ENSPPAP00000010021

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032670 ⟹ ENSPPAP00000010023

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032671 ⟹ ENSPPAP00000010024

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032672 ⟹ ENSPPAP00000010025

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032675 ⟹ ENSPPAP00000010028

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,942 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032681 ⟹ ENSPPAP00000010034

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,765,859 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000032683 ⟹ ENSPPAP00000010036

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	19	55,747,722 - 55,760,409 (+)	Ensembl

RefSeq Acc Id:

XM_008966986 ⟹ XP_008965234

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,933,021 - 55,952,578 (+)	NCBI
NHGRI_mPanPan1	19	57,853,775 - 57,873,367 (+)	NCBI
Mhudiblu_PPA_v0	19	46,831,191 - 46,849,963 (+)	NCBI
PanPan1.1	19	55,747,445 - 55,765,978 (+)	NCBI

Sequence:

show sequence

ACTGAGCCGCTCTCTATTTAGCTCTTGACAATAATTCCGTCTAACCCATCTAGGCCCCTAGAAG
GGCTAACTATGCCCTTTCTGAGTCTTCCACGCGGTGGGGGCGAAGGAGGATTGAGCTAGAACGA
GGCTTCAGCGCGTGCCCCGCACAAACATGGCAGCATTCCCAGCAGCCCTAAACCGCCCGACGCG
GGCGCGCGCGCGGCGCAGGCGCATTTCCGCTCATTCCGCGGCGTCGGCTGCGGCGGCAGTGGCG
GTGGCGGGTACCGCACGGGGTATGGTCCCCGGGTCCGAGGGCCCGGCCCGCGCCGGGAGCGTGG
TGGCCGACGTGGTGTTTGTGATTGAGGGTACGGCCAACCTGGGACCCTACTTCGAGGGGCTCCG
CAAGCACTACCTGCTCCCGGCCATCGAGTATTTTAATGGTGGTCCTCCTGCTGAGACGGACTTC
GGGGGAGACTATGGGGGGACCCAGTACAGCCTCGTGGTGTTCAACACAGTGGACTGCGCTCCCG
AGTCCTACGTACAATGTCACGCTCCCACCAGCAGCGCCTATGAGTTTGTCACCTGGCTCGATGG
CATTAAGTTCATGGGCGGGGGTGGTGAGAGCTGCAGCCTCATCGCGGAAGGACTCAGCACAGCC
TTGCAGCTGTTTGATGACTTCAAGAAGATGCGCGAGCAGATTGGCCAGACGCACCGGGTCTGCC
TCCTCATCTGCAACTCACCCCCATACTTGTTGCCTGCTGTTGAGAGCACCACGTACTCTGGATG
CACAACTGAGAATCTTGTGCAGCAGATTGGGGAGCGGGGGATCCACTTCTCCATCGTGTCTCCC
CGGAAGCTGCCTGCGCTTCGGCTTCTGTTTGAGAAGGCAGCCCCTCCGGCCTTGCTGGAGCCGC
TGCAGCCTCCGACAGATGTGAGCCAGGACCCGAGGCACATGGTGCTGGTTCGGGGACTCGTGCT
GCCTGTTGGGGGTGGCTCAGCCCCAGGCCCCCTCCAGTCAAAGCAGCCAGTCCCCCTGCCTCCC
GCCACACCCTCAGGTGCCACTCTCTCAGCAGCTCCCCAGCAGCCTCTGCCCCCCGTCCCCCCGC
AGTACCAGGTTCCCGGGAACCTGAGTGCAGCTCAGGTGGCTGCGCAGAATGCAGTGGAGGCTGC
CAAGAACCAGAAGGCTGGGCTGGGCCCTCGCTTCTCGCCCATCACCCCTCTCCAACAAGCTGCT
CCCGGAGTGGGTCCCCCCTTCAGCCAGGCCCCAGCTCCCCAGCTACCCCCAGGACCCCCTGGCG
CCCCCAAGCCACCACCTGCTTCCCAGCCCAGTCTGGTCTCCACCGTGGCCCCTGGCTCCGGCCT
GGCTCCCACGGCACAGCCCGGGGCACCGTCCATGGCAGGCACTGTGGCCCCAGGAGGGGTGAGC
GGCCCTTCCCCAGCCCAGCTGGGAGCCCCAGCCCTCGGTGGGCAGCAGTCAGTCTCCAATAAGC
TTCTGGCCTGGAGCGGGGTCTTGGAGTGGCAAGAGAAACCCAAACCTGCCTCAGTGGATGCCAA
CACCAAGCTGACGCGGTCACTGCCCTGCCAGGTCTACGTGAATCATGGCGAGAACCTGAAGACG
GAGCAGTGGCCCCAGAAGCTGATCATGCAGCTCATCCCCCAGCAGCTGCTGACCACCCTGGGCC
CTTTGTTCCGGAACTCAAGGATGGTCCAGTTCCATTTCACCAACAAGGACCTGGAGTCTCTCAA
AGGCCTCTACCGCATCATGGGCAACGGCTTCGCGGGCTGCGTGCACTTCCCCCACACGGCGCCC
TGTGAGGTGCGTGTGCTCATGCTCCTGTACTCGTCCAAGAAGAAGATCTTCATGGGCCTCATCC
CCTACGACCAGAGCGGCTTCGTCAACGGCATCCGGCAGGTCATCACCAACCACAAGCAGGTCCA
GCAGCAGAAGCTGGAGCAGCAGCAGCGAGGAATGGGGGGACAGCAGGCACCCCCAGGGCTGGGG
CCCATTCTGGAGGACCAAGCAAGGCCCTCACAGAATCTGCTCCAGCTCCGCCCACCACAGCCCC
AGCCTCAGGGTACCGTAGGGGCCTCTGGGGCCACGGGGCAGCCCCAGCCCCAAGGTACTGCCCA
GCCCCCCCCAGGTGCCCCCCAAGGCCCTCCTGGAGCAGCTTCTGGCCCACCCCCTCCTGGACCC
ATCCTTCGGCCCCAGAACCCTGGGGCCAACCCCCAGCTGCGAAGCCTCCTCCTCAACCCACCAC
CGCCGCAGACTGGGGTGCCCCCACCCCAGGCCTCCCTCCACCACCTCCAGCCACCAGGGGCTCC
TGCGCTGCTGCCTCCGCCGCACCAGGGCCTGGGGCAGCCCCAGTTGGGGCCCCCACTCCTGCAT
CCACCACCTGCCCAGTCCTGGCCCGCACAACTTCCCCCGCGGGCTCCACTGCCAGGTCAGATGC
TGCTGAGCGGGGGTCCCCGGGGCCCGGTCCCCCAGCCGGGCCTGCAGCCCAGCGTCATGGAGGA
CGACATCCTCATGGATCTCATCTGAATCCCCAACACCCAATAAAGTTCCTTTTTAACACAC

hide sequence

RefSeq Acc Id:

XM_034945439 ⟹ XP_034801330

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,933,025 - 55,955,983 (+)	NCBI
NHGRI_mPanPan1	19	57,853,779 - 57,876,771 (+)	NCBI
Mhudiblu_PPA_v0	19	46,831,190 - 46,853,367 (+)	NCBI

RefSeq Acc Id:

XM_055103350 ⟹ XP_054959325

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,933,178 - 55,955,983 (+)	NCBI
NHGRI_mPanPan1	19	57,853,932 - 57,876,771 (+)	NCBI

RefSeq Acc Id:

XM_055103352 ⟹ XP_054959327

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,933,025 - 55,952,578 (+)	NCBI
NHGRI_mPanPan1	19	57,853,779 - 57,873,367 (+)	NCBI

RefSeq Acc Id:

XM_055103353 ⟹ XP_054959328

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,934,915 - 55,955,983 (+)	NCBI
NHGRI_mPanPan1	19	57,855,706 - 57,876,771 (+)	NCBI

RefSeq Acc Id:

XM_063600517 ⟹ XP_063456587

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,933,025 - 55,952,578 (+)	NCBI

RefSeq Acc Id:

XM_063600518 ⟹ XP_063456588

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	20	55,934,915 - 55,955,983 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008965234	(Get FASTA)	NCBI Sequence Viewer
	XP_034801330	(Get FASTA)	NCBI Sequence Viewer
	XP_054959325	(Get FASTA)	NCBI Sequence Viewer
	XP_054959327	(Get FASTA)	NCBI Sequence Viewer
	XP_054959328	(Get FASTA)	NCBI Sequence Viewer
	XP_063456587	(Get FASTA)	NCBI Sequence Viewer
	XP_063456588	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000010012.1
	ENSPPAP00000010014.1
	ENSPPAP00000010021.1
	ENSPPAP00000010023.1
	ENSPPAP00000010024.1
	ENSPPAP00000010025.1
	ENSPPAP00000010028.1
	ENSPPAP00000010034.1
	ENSPPAP00000010036.1

RefSeq Acc Id:	XP_008965234 ⟸ XM_008966986
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAAFPAALNRPTRARARRRRISAHSAASAAAAVAVAGTARGMVPGSEGPARAGSVVADVVFVIE GTANLGPYFEGLRKHYLLPAIEYFNGGPPAETDFGGDYGGTQYSLVVFNTVDCAPESYVQCHAP TSSAYEFVTWLDGIKFMGGGGESCSLIAEGLSTALQLFDDFKKMREQIGQTHRVCLLICNSPPY LLPAVESTTYSGCTTENLVQQIGERGIHFSIVSPRKLPALRLLFEKAAPPALLEPLQPPTDVSQ DPRHMVLVRGLVLPVGGGSAPGPLQSKQPVPLPPATPSGATLSAAPQQPLPPVPPQYQVPGNLS AAQVAAQNAVEAAKNQKAGLGPRFSPITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQ PSLVSTVAPGSGLAPTAQPGAPSMAGTVAPGGVSGPSPAQLGAPALGGQQSVSNKLLAWSGVLE WQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMV QFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVN GIRQVITNHKQVQQQKLEQQQRGMGGQQAPPGLGPILEDQARPSQNLLQLRPPQPQPQGTVGAS GATGQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQTGVPPP QASLHHLQPPGAPALLPPPHQGLGQPQLGPPLLHPPPAQSWPAQLPPRAPLPGQMLLSGGPRGP VPQPGLQPSVMEDDILMDLI hide sequence

RefSeq Acc Id:	XP_034801330 ⟸ XM_034945439
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000010012 ⟸ ENSPPAT00000032659

Ensembl Acc Id:

ENSPPAP00000010034 ⟸ ENSPPAT00000032681

Ensembl Acc Id:

ENSPPAP00000010036 ⟸ ENSPPAT00000032683

Ensembl Acc Id:

ENSPPAP00000010028 ⟸ ENSPPAT00000032675

Ensembl Acc Id:

ENSPPAP00000010023 ⟸ ENSPPAT00000032670

Ensembl Acc Id:

ENSPPAP00000010025 ⟸ ENSPPAT00000032672

Ensembl Acc Id:

ENSPPAP00000010024 ⟸ ENSPPAT00000032671

Ensembl Acc Id:

ENSPPAP00000010021 ⟸ ENSPPAT00000032668

Ensembl Acc Id:

ENSPPAP00000010014 ⟸ ENSPPAT00000032661

RefSeq Acc Id:	XP_054959327 ⟸ XM_055103352
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054959325 ⟸ XM_055103350
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054959328 ⟸ XM_055103353
- Peptide Label:	isoform X7
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063456587 ⟸ XM_063600517
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063456588 ⟸ XM_063600518
- Peptide Label:	isoform X6
- UniProtKB:	A0A2R8ZYH5 (UniProtKB/TrEMBL)

Protein Domains

Mediator complex subunit Med25 PTOV Mediator complex subunit Med25 synapsin Mediator of RNA polymerase II transcription subunit

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000028184	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000032659.1	UniProtKB/TrEMBL
	ENSPPAT00000032661.1	UniProtKB/TrEMBL
	ENSPPAT00000032668.1	UniProtKB/TrEMBL
	ENSPPAT00000032670.1	UniProtKB/TrEMBL
	ENSPPAT00000032671.1	UniProtKB/TrEMBL
	ENSPPAT00000032672.1	UniProtKB/TrEMBL
	ENSPPAT00000032675.1	UniProtKB/TrEMBL
	ENSPPAT00000032681.1	UniProtKB/TrEMBL
	ENSPPAT00000032683.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.290.30	UniProtKB/TrEMBL
InterPro	Med25_PTOV	UniProtKB/TrEMBL
	Med25_PTOV_sf	UniProtKB/TrEMBL
	Mediator_Med25_SD1	UniProtKB/TrEMBL
	Mediator_Med25_VWA	UniProtKB/TrEMBL
	vWFA_dom_sf	UniProtKB/TrEMBL
NCBI Gene	MED25	ENTREZGENE
PANTHER	MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25	UniProtKB/TrEMBL
	PTHR12433	UniProtKB/TrEMBL
Pfam	Med25	UniProtKB/TrEMBL
	Med25_SD1	UniProtKB/TrEMBL
	Med25_VWA	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53300	UniProtKB/TrEMBL
UniProt	A0A2R8ZYG3_PANPA	UniProtKB/TrEMBL
	A0A2R8ZYH5	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZYH7_PANPA	UniProtKB/TrEMBL
	A0A2R8ZZL3_PANPA	UniProtKB/TrEMBL
	A0A2R8ZZL8_PANPA	UniProtKB/TrEMBL
	A0A2R9A2I8_PANPA	UniProtKB/TrEMBL
	A0A2R9A2J9_PANPA	UniProtKB/TrEMBL
	A0A2R9A2K9_PANPA	UniProtKB/TrEMBL
	A0A2R9A414_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

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