ANO6 (anoctamin 6) - Rat Genome Database

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Gene: ANO6 (anoctamin 6) Pan paniscus
Analyze
Symbol: ANO6
Name: anoctamin 6
RGD ID: 11699999
Description: ENCODES a protein that exhibits identical protein binding (ortholog); intracellularly calcium-gated chloride channel activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN blood coagulation (ortholog); bone mineralization involved in bone maturation (ortholog); calcium activated galactosylceramide scrambling (ortholog); ASSOCIATED WITH ankylosing spondylitis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN cholinergic synapse (ortholog); synaptic membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: anoctamin-6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21048,733,953 - 48,950,131 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11248,730,709 - 48,947,193 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01243,295,928 - 43,512,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11244,164,375 - 44,380,261 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1244,164,375 - 44,303,259 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ANO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21048,733,953 - 48,950,131 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11248,730,709 - 48,947,193 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01243,295,928 - 43,512,073 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11244,164,375 - 44,380,261 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1244,164,375 - 44,303,259 (-)Ensemblpanpan1.1panPan2
ANO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381245,216,095 - 45,440,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1245,215,987 - 45,482,280 (+)EnsemblGRCh38hg38GRCh38
GRCh371245,609,878 - 45,834,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,896,170 - 44,112,399 (+)NCBINCBI36Build 36hg18NCBI36
Celera1244,413,462 - 44,637,876 (+)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1242,638,190 - 42,862,629 (+)NCBIHuRef
CHM1_11245,574,740 - 45,799,189 (+)NCBICHM1_1
T2T-CHM13v2.01245,174,737 - 45,399,096 (+)NCBIT2T-CHM13v2.0
Ano6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391595,688,724 - 95,873,353 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1595,688,724 - 95,872,632 (+)EnsemblGRCm39 Ensembl
GRCm381595,790,843 - 95,975,472 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1595,790,843 - 95,974,751 (+)EnsemblGRCm38mm10GRCm38
MGSCv371595,621,274 - 95,805,205 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361595,618,877 - 95,802,808 (+)NCBIMGSCv36mm8
Celera1597,939,179 - 98,118,870 (+)NCBICelera
Cytogenetic Map15E3- F1NCBI
cM Map1550.66NCBI
Ano6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87128,812,842 - 128,992,805 (+)NCBIGRCr8
mRatBN7.27126,933,919 - 127,113,588 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7126,933,936 - 127,113,589 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7128,733,569 - 128,913,454 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07130,959,091 - 131,138,975 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07130,864,863 - 131,044,680 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07137,142,063 - 137,335,208 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7137,142,170 - 137,335,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07136,781,570 - 136,973,259 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47134,434,775 - 134,624,126 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17134,511,298 - 134,697,841 (+)NCBI
Celera7123,442,149 - 123,619,990 (+)NCBICelera
Cytogenetic Map7q35NCBI
Ano6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555004,462,524 - 4,652,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555004,462,314 - 4,652,634 (+)NCBIChiLan1.0ChiLan1.0
ANO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1278,882,691 - 9,067,057 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl278,884,062 - 9,066,934 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2737,246,426 - 37,430,774 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0279,072,368 - 9,257,318 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl279,074,398 - 9,257,197 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,878,877 - 9,063,444 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0278,918,866 - 9,103,666 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02737,484,107 - 37,668,815 (+)NCBIUU_Cfam_GSD_1.0
Ano6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494569,429,550 - 69,515,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365123,540,129 - 3,732,776 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365123,649,103 - 3,736,274 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl576,113,236 - 76,337,069 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1576,112,428 - 76,337,073 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2578,998,214 - 79,219,973 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11141,420,206 - 41,633,323 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1141,419,901 - 41,633,347 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037204,821,696 - 205,033,977 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ano6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248166,894,413 - 7,077,883 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248166,896,176 - 7,077,758 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000049575   ⟹   ENSPPAP00000026739
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1244,164,375 - 44,303,259 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000049578   ⟹   ENSPPAP00000026742
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1244,167,403 - 44,294,859 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000049581   ⟹   ENSPPAP00000026745
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1244,167,403 - 44,294,658 (-)Ensembl
RefSeq Acc Id: XM_003825754   ⟹   XP_003825802
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21048,733,953 - 48,950,131 (-)NCBI
NHGRI_mPanPan11248,730,709 - 48,947,189 (-)NCBI
Mhudiblu_PPA_v01243,295,928 - 43,512,073 (-)NCBI
PanPan1.11244,164,375 - 44,380,261 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951088   ⟹   XP_008949336
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21048,733,953 - 48,950,065 (-)NCBI
NHGRI_mPanPan11248,730,709 - 48,946,664 (-)NCBI
Mhudiblu_PPA_v01243,295,928 - 43,512,007 (-)NCBI
PanPan1.11244,164,377 - 44,380,261 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014347200   ⟹   XP_014202686
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21048,733,953 - 48,950,120 (-)NCBI
NHGRI_mPanPan11248,730,709 - 48,946,823 (-)NCBI
Mhudiblu_PPA_v01243,295,928 - 43,512,034 (-)NCBI
PanPan1.11244,164,375 - 44,380,261 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055095730   ⟹   XP_054951705
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21048,741,658 - 48,950,131 (-)NCBI
NHGRI_mPanPan11248,733,953 - 48,947,193 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003825802 (Get FASTA)   NCBI Sequence Viewer  
  XP_008949336 (Get FASTA)   NCBI Sequence Viewer  
  XP_014202686 (Get FASTA)   NCBI Sequence Viewer  
  XP_054951705 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000026739.1
  ENSPPAP00000026742.1
  ENSPPAP00000026745.1
RefSeq Acc Id: XP_014202686   ⟸   XM_014347200
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BC91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003825802   ⟸   XM_003825754
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BC91 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949336   ⟸   XM_008951088
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BC91 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000026742   ⟸   ENSPPAT00000049578
Ensembl Acc Id: ENSPPAP00000026739   ⟸   ENSPPAT00000049575
Ensembl Acc Id: ENSPPAP00000026745   ⟸   ENSPPAT00000049581
RefSeq Acc Id: XP_054951705   ⟸   XM_055095730
- Peptide Label: isoform X4

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036432 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000049575.1 UniProtKB/TrEMBL
  ENSPPAT00000049578.1 UniProtKB/TrEMBL
  ENSPPAT00000049581.1 UniProtKB/TrEMBL
InterPro Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
  Anoctamin_TM UniProtKB/TrEMBL
NCBI Gene ANO6 ENTREZGENE
PANTHER PTHR12308 UniProtKB/TrEMBL
  PTHR12308:SF21 UniProtKB/TrEMBL
Pfam Anoct_dimer UniProtKB/TrEMBL
  Anoctamin UniProtKB/TrEMBL
UniProt A0A2R9BAV4_PANPA UniProtKB/TrEMBL
  A0A2R9BC91 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BIY8_PANPA UniProtKB/TrEMBL