ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide) - Rat Genome Database

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Gene: ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide) Pan paniscus
Analyze
Symbol: ADH1B (Ensembl: ADH1C)
Name: alcohol dehydrogenase 1B (class I), beta polypeptide (Ensembl:alcohol dehydrogenase 1C (class I), gamma polypeptide)
RGD ID: 11697738
Description: ENCODES a protein that exhibits alcohol dehydrogenase (NAD+) activity (inferred); alcohol dehydrogenase (NAD+) activity, zinc-dependent (inferred); all-trans-retinol dehydrogenase (NAD+) activity (inferred); INVOLVED IN retinoid metabolic process (ortholog); PARTICIPATES IN celecoxib pharmacodynamics pathway; celecoxib pharmacokinetics pathway; disulfiram pharmacodynamics pathway; ASSOCIATED WITH Acute Liver Failure (ortholog); Aerodigestive Tract Squamous Cell Carcinoma (ortholog); alcohol dependence (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alcohol dehydrogenase 1B; all-trans-retinol dehydrogenase [NAD(+)] ADH1B; LOC100971090
RGD Orthologs
Human
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,385,352 - 97,400,802 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,669,030 - 97,683,998 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,726,870 - 91,741,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,388,575 - 102,403,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,388,575 - 102,435,079 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADH1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,385,352 - 97,400,802 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,669,030 - 97,683,998 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,726,870 - 91,741,824 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,388,575 - 102,403,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,388,575 - 102,435,079 (-)Ensemblpanpan1.1panPan2
ADH1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,304,971 - 99,321,401 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,304,971 - 99,321,401 (-)EnsemblGRCh38hg38GRCh38
GRCh374100,226,128 - 100,242,558 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,446,552 - 100,461,581 (-)NCBINCBI36Build 36hg18NCBI36
Build 344100,584,706 - 100,599,736NCBI
Celera497,524,703 - 97,539,748 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef495,965,328 - 95,980,374 (-)NCBIHuRef
CHM1_14100,203,933 - 100,218,979 (-)NCBICHM1_1
T2T-CHM13v2.04102,619,785 - 102,636,182 (-)NCBIT2T-CHM13v2.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000051465   ⟹   ENSPPAP00000028617
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4102,388,575 - 102,403,521 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051473   ⟹   ENSPPAP00000028625
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4102,389,915 - 102,434,709 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000051477   ⟹   ENSPPAP00000028629
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4102,416,418 - 102,435,079 (-)Ensembl
RefSeq Acc Id: XM_003829928   ⟹   XP_003829976
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2397,385,352 - 97,400,802 (-)NCBI
NHGRI_mPanPan1497,669,030 - 97,683,998 (-)NCBI
Mhudiblu_PPA_v0491,726,870 - 91,741,824 (-)NCBI
PanPan1.14102,388,575 - 102,403,521 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003829976 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028617
  ENSPPAP00000028617.1
  ENSPPAP00000028625.1
Reference Protein Sequences
RefSeq Acc Id: XP_003829976   ⟸   XM_003829928
- UniProtKB: A0A2R9BG66 (UniProtKB/TrEMBL),   A0A2R8ZNF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000028629   ⟸   ENSPPAT00000051477
RefSeq Acc Id: ENSPPAP00000028617   ⟸   ENSPPAT00000051465
RefSeq Acc Id: ENSPPAP00000028625   ⟸   ENSPPAT00000051473
Protein Domains
Enoyl reductase (ER)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037337 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051465.1 UniProtKB/TrEMBL
  ENSPPAT00000051473.1 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/TrEMBL
  ADH_N UniProtKB/TrEMBL
  ADH_Zn_CS UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  PKS_ER UniProtKB/TrEMBL
KEGG Report pps:100971090 UniProtKB/TrEMBL
NCBI Gene LOC100971090 ENTREZGENE
PANTHER ALCOHOL DEHYDROGENASE UniProtKB/TrEMBL
  ALL-TRANS-RETINOL DEHYDROGENASE [NAD(+)] ADH1B UniProtKB/TrEMBL
Pfam ADH_N UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/TrEMBL
PROSITE ADH_ZINC UniProtKB/TrEMBL
SMART PKS_ER UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
UniProt A0A2R8ZNF0 ENTREZGENE
  A0A2R9BG66 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 ADH1B  alcohol dehydrogenase 1B (class I), beta polypeptide  LOC100971090  alcohol dehydrogenase 1B  Symbol and/or name change 5135510 APPROVED