PDLIM3 (PDZ and LIM domain 3) - Rat Genome Database

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Gene: PDLIM3 (PDZ and LIM domain 3) Pan paniscus
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Symbol: PDLIM3
Name: PDZ and LIM domain 3
RGD ID: 11691209
Description: ENCODES a protein that exhibits actinin binding (ortholog); cytoskeletal protein binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN actin filament organization (ortholog); heart development (ortholog); skeletal muscle tissue development (ortholog); ASSOCIATED WITH arrhythmogenic right ventricular cardiomyopathy (ortholog); autistic disorder (ortholog); cardiomyopathy (ortholog); FOUND IN actin cytoskeleton (ortholog); Z disc (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PDZ and LIM domain protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23183,236,644 - 183,270,599 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14183,584,749 - 183,618,714 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04177,664,420 - 177,698,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,880,930 - 189,914,707 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,880,938 - 189,914,707 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PDLIM3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23183,236,644 - 183,270,599 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14183,584,749 - 183,618,714 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04177,664,420 - 177,698,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,880,930 - 189,914,707 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,880,938 - 189,914,707 (-)Ensemblpanpan1.1panPan2
PDLIM3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384185,500,660 - 185,535,507 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4185,500,660 - 185,535,507 (-)EnsemblGRCh38hg38GRCh38
GRCh374186,421,814 - 186,456,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364186,659,899 - 186,693,650 (-)NCBINCBI36Build 36hg18NCBI36
Build 344186,798,059 - 186,831,794NCBI
Celera4183,749,238 - 183,781,710 (-)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4182,175,438 - 182,209,519 (-)NCBIHuRef
CHM1_14186,398,441 - 186,430,909 (-)NCBICHM1_1
T2T-CHM13v2.04188,844,192 - 188,876,603 (-)NCBIT2T-CHM13v2.0
Pdlim3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39846,338,524 - 46,372,672 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl846,338,498 - 46,372,585 (+)EnsemblGRCm39 Ensembl
GRCm38845,885,487 - 45,919,635 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl845,885,461 - 45,919,548 (+)EnsemblGRCm38mm10GRCm38
MGSCv37846,970,839 - 47,004,900 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36847,384,302 - 47,418,363 (+)NCBIMGSCv36mm8
Celera848,569,007 - 48,602,415 (+)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map825.86NCBI
Pdlim3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81653,085,020 - 53,116,495 (-)NCBIGRCr8
mRatBN7.21646,352,460 - 46,383,680 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1646,352,467 - 46,383,657 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1651,754,729 - 51,785,861 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01655,123,468 - 55,154,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01650,394,110 - 50,425,252 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01649,543,140 - 49,574,362 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1649,543,142 - 49,574,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01649,271,210 - 49,303,161 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41649,637,068 - 49,668,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11649,637,142 - 49,668,877 (-)NCBI
Celera1644,350,214 - 44,381,388 (-)NCBICelera
Cytogenetic Map16q11NCBI
Pdlim3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540323,546,291 - 23,579,975 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540323,546,291 - 23,579,975 (+)NCBIChiLan1.0ChiLan1.0
PDLIM3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,111,358 - 45,141,444 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,111,372 - 45,140,895 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1645,596,679 - 45,626,635 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01647,324,629 - 47,354,794 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1647,324,611 - 47,354,792 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11645,292,955 - 45,322,927 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01645,905,420 - 45,935,439 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,036,947 - 46,067,096 (+)NCBIUU_Cfam_GSD_1.0
Pdlim3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494334,235,812 - 34,265,116 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365543,844,743 - 3,874,174 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365543,844,896 - 3,874,168 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDLIM3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1546,513,449 - 46,546,507 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11546,516,178 - 46,546,658 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21553,297,824 - 53,328,219 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDLIM3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17131,443,131 - 131,477,575 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7131,441,674 - 131,477,554 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037111,704,011 - 111,738,337 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdlim3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476916,340,494 - 16,374,208 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476916,341,297 - 16,374,106 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000044177   ⟹   ENSPPAP00000021375
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4189,880,938 - 189,914,707 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044181   ⟹   ENSPPAP00000021379
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4189,880,938 - 189,914,653 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044183   ⟹   ENSPPAP00000021381
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4189,880,938 - 189,914,653 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044188   ⟹   ENSPPAP00000021386
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl4189,881,464 - 189,914,535 (-)Ensembl
RefSeq Acc Id: XM_003823480   ⟹   XP_003823528
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23183,236,644 - 183,270,599 (-)NCBI
NHGRI_mPanPan14183,584,749 - 183,618,714 (-)NCBI
Mhudiblu_PPA_v04177,664,420 - 177,698,360 (-)NCBI
PanPan1.14189,880,930 - 189,914,707 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003823481   ⟹   XP_003823529
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v23183,236,644 - 183,270,599 (-)NCBI
NHGRI_mPanPan14183,584,749 - 183,618,714 (-)NCBI
Mhudiblu_PPA_v04177,664,420 - 177,698,364 (-)NCBI
PanPan1.14189,880,930 - 189,914,653 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003823528 (Get FASTA)   NCBI Sequence Viewer  
  XP_003823529 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021375.1
  ENSPPAP00000021379.1
  ENSPPAP00000021381.1
  ENSPPAP00000021386.1
RefSeq Acc Id: XP_003823528   ⟸   XM_003823480
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003823529   ⟸   XM_003823481
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSPPAP00000021375   ⟸   ENSPPAT00000044177
RefSeq Acc Id: ENSPPAP00000021381   ⟸   ENSPPAT00000044183
RefSeq Acc Id: ENSPPAP00000021379   ⟸   ENSPPAT00000044181
RefSeq Acc Id: ENSPPAP00000021386   ⟸   ENSPPAT00000044188
Protein Domains
LIM zinc-binding   PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033898 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044177.1 UniProtKB/TrEMBL
  ENSPPAT00000044181.1 UniProtKB/TrEMBL
  ENSPPAT00000044183.1 UniProtKB/TrEMBL
  ENSPPAT00000044188.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  Cysteine Rich Protein UniProtKB/TrEMBL
InterPro DUF4749 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Zasp-like_motif UniProtKB/TrEMBL
  Znf_LIM UniProtKB/TrEMBL
KEGG Report pps:100981687 UniProtKB/TrEMBL
NCBI Gene PDLIM3 ENTREZGENE
PANTHER PDZ AND LIM DOMAIN PROTEIN 3 UniProtKB/TrEMBL
  PDZ AND LIM DOMAIN PROTEIN ZASP UniProtKB/TrEMBL
Pfam DUF4749 UniProtKB/TrEMBL
  LIM UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART LIM UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SM00735 UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/TrEMBL
  SSF50156 UniProtKB/TrEMBL
UniProt A0A2R9AVT7_PANPA UniProtKB/TrEMBL
  A0A2R9AVU3_PANPA UniProtKB/TrEMBL
  A0A2R9AZT1_PANPA UniProtKB/TrEMBL
  A0A2R9B1T1_PANPA UniProtKB/TrEMBL