MPP4 (membrane palmitoylated protein 4)

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Gene: MPP4 (membrane palmitoylated protein 4) Pan paniscus

Analyze

Symbol:

MPP4

Name:

membrane palmitoylated protein 4

RGD ID:

11690540

Description:

ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN protein localization to synapse (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); Joubert syndrome 14 (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN actin cytoskeleton (ortholog); adherens junction (ortholog); basal part of cell (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

MAGUK p55 subfamily member 4

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	207,052,927 - 207,102,360 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	88,898,091 - 88,951,597 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Developmental Disabilities (ISO)

Joubert syndrome 14 (ISO)

Neurodevelopmental Disorders (ISO)

Pulmonary Arterial Hypertension (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

protein localization to synapse (ISO)

Cellular Component

actin cytoskeleton (ISO)

adherens junction (ISO)

basal part of cell (ISO)

cone cell pedicle (ISO)

cytosol (ISO)

Golgi membrane (ISO)

lateral plasma membrane (ISO)

presynaptic membrane (ISO)

protein-containing complex (ISO)

rod spherule (ISO)

Molecular Function

protein binding (ISO)

signaling receptor binding (ISO)

References

Genomics

Comparative Map Data

MPP4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	207,052,927 - 207,102,360 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	88,898,091 - 88,951,597 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

MPP4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	2	201,644,870 - 201,698,694 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	2	201,644,874 - 201,700,263 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	2	202,509,597 - 202,563,367 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	202,217,865 - 202,271,662 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	2	202,335,125 - 202,388,923	NCBI
Celera	2	196,261,499 - 196,315,217 (-)	NCBI
Cytogenetic Map	2	q33.1	NCBI
HuRef	2	194,357,715 - 194,411,441 (-)	NCBI		HuRef
CHM1_1	2	202,516,116 - 202,569,904 (-)	NCBI		CHM1_1

Mpp4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	59,160,094 - 59,202,548 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	1	59,160,094 - 59,202,548 (-)	Ensembl
GRCm38	1	59,120,935 - 59,163,389 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	59,120,935 - 59,163,389 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	59,177,779 - 59,220,233 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	59,065,481 - 59,103,214 (-)	NCBI			mm8
Celera	1	59,637,173 - 59,679,621 (-)	NCBI		Celera
Cytogenetic Map	1	C1.3	NCBI

Mpp4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	60,569,734 - 60,613,035 (-)	NCBI
Rnor_6.0 Ensembl	9	65,917,917 - 65,957,101 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	9	65,917,917 - 65,961,274 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	9	65,725,150 - 65,767,400 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	57,696,943 - 57,736,126 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	57,843,928 - 57,877,524 (-)	NCBI
Celera	9	58,007,768 - 58,046,959 (-)	NCBI		Celera
Cytogenetic Map	9	q31	NCBI

Mpp4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	109,353 - 147,035 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	109,353 - 147,442 (+)	NCBI	ChiLan1.0	ChiLan1.0

MPP4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	37	10,711,597 - 10,748,889 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	37	10,711,324 - 10,751,329 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Mpp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936726	893,411 - 938,876 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MPP4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	105,276,822 - 105,319,030 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	105,277,295 - 105,319,936 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MPP4
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	87,328,555 - 87,382,894 (-)	NCBI
ChlSab1.1 Ensembl	10	87,328,962 - 87,382,232 (-)	Ensembl

Mpp4
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624899	175,920 - 205,398 (+)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008974194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	SSBP01000166	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000048071 ⟹ ENSPPAP00000025244

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048073 ⟹ ENSPPAP00000025246

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048074 ⟹ ENSPPAP00000025247

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000048076 ⟹ ENSPPAP00000025249

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2B	207,053,077 - 207,102,360 (-)	Ensembl

RefSeq Acc Id:

XM_008974194 ⟹ XP_008972442

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1	2B	207,052,927 - 207,102,360 (-)	NCBI
Mhudiblu_PPA_v0	2B	88,898,091 - 88,951,597 (-)	NCBI

Sequence:

show sequence

ATGATACAGTCAGACAAAGGAGCAGATCCACCAGACCAGAAGGACATGAAGCTTTCTACAGCCA
CCAATCCACAGAATGGCCTCTCCCAGATCCTGAGGCTTGTGCTGCAAGAGCTGAGTCTGTTCTA
CAGCAGAGATGTGAATGGGGTGTGTCTCTTGTACGATCTCCTCCACTCGCCGTGGCTTCAGGCT
CTGCTAAAGATTTATGACTGCCTCCAGGAATTTAAAGAAAAGAAACTAGTTCCTGCCACACCAC
AAGCACAGGTGTTATCCTATGAGGTAGTGGAGTTATTACGTGAAACCCCTACTTCCCCTGAGAT
CCAAGAGCTGAGACAAATGCTCCAGGCTCCACACTTCAAGGCCTTGCTCAGTGCCCATGACACG
ATAGCTCAGAAAGATTTTGAACCCCTTCTCCCTCCACTGCCAGACAATATCCCTGAGAGTGAGG
AAGCAATGAGGATTGTTTGTTTAGTGAAAAACCAACAGCCCCTGGGAGCCACCATCAAGCGCCA
CGAGATGACAGGGGACATCTTGGTGGCCAGGATCATCCACGGTGGGCTGGCGGAGAGAAGTGGG
TTGCTATATGCTGGAGACAAACTGGTAGAAGTGAATGGAGTTTCAGTTGAGGGACTGGACCCTG
AACAAGTGATCCATATTCTGGCCATGTCTCGAGGCACAATCATGTTCAAGGTGGTTCCAGTCTC
TGACCCTCCTGTGAATAGCCAGAAGATGGTGTACGTCCGTGCCATGACTGAGTACTGGCCCCAG
GAGGATCCCGACATCCCCTGCATGGACGCTGGATTGCCTTTCCAGAAGGGGGACATCCTCCAGA
TTGTGGACCAGAATGATGCCCTCTGGTGGCAGGCCCGAAAAATCTCAGACCCTGCTACCTGCGC
TGGGCTTGTCCCTTCTAACCACCTTCTGAAGAGGAAGCAACGGGAATTCTGGTGGTCTCAGCCG
TACCAGCCTCACACCTGCCTCAAGTCAACACTATCAATTTCTATGGAAGAAGAAGATGACATGA
AGATTGATGAGAAATGTGTGGAAGCAGATGAAGAAACATTTGAATCTGAGGAACTTTCAGAAGA
CAAGGAGGAATTTGTTGGCTACGGTCAGAAGTTCTTTATAGCTGGCTTCCGCCGCAGCATGCGC
CTTTGTCGCAGGAAGTCTCACCTCAGCCCGCTGCATGCCAGTGTGTGCTGCACCGGCAGCTGCT
ACAGTGCAGTGGGTGCCCCTTACGAGGAGGTGGTGAGGTACCAGCGACGCCCTTCAGACAAGTA
CCGCCTCATAGTGCTCATGGGACCCTCTGGTGTTGGAGTAAATGAGCTCAGAAGACAACTTATT
GAATTTAATCCCAGCCATTTTCAAAGTGCTGTGCCACACACTACTCGTACTAAAAAGAGTTATG
AAATGAATGGGCGTGAGTATCACTATGTGTCCAAGGAAACATTTGAAAGCCTCATATATAGTCA
CAGGATGCTGGAGTATGGTGAGTACAAAGGCCACCTGTATGGCACTAGTGTGGATGCTGTTCAA
ACAGTCCTTGTCGAAGGAAAGATCTGTGTCATGGACTTAGAGCCTCAGGATATTCAAGGGGTTC
GAACCCATGAACTGAAGCCCTATGTCATATTTATAAAGCCATCGAATATGAGGTGTATGAAACA
ATCTCGGAAAAATGCCAAGATTATTACTGACTACTATGTGGACATGAAGTTCAAGGATGAAGAC
CTACAAGAGATGGAAAATTTAGCCCAAAGAATGGAAACTCAGTTTGGCCAATTTTTTGATCATG
TGATTGTGAATGACAGCTTGCACGATGCATGTGCCCAGTTGTTGTCTGCCATACAGAAGGCTCA
GGAGGAGCCTCAGTGGGTACCAGCAACATGGATTACCTCAGATACTGAGTCTTAATGAGACTTC
TTGTTTAATGCTGGAGTTTTAACACTGTACCCTTGATACAGCGATCCATAGTTGCAATCTAAAA
CAACAGTATTTGACCCATTTTAATGTGTACAACTTTAAAAGTGCAGCAGTTTATTAATTAATCT
TATTTGAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_008972442	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_008972442 ⟸ XM_008974194

- Sequence:

show sequence

MIQSDKGADPPDQKDMKLSTATNPQNGLSQILRLVLQELSLFYSRDVNGVCLLYDLLHSPWLQA
LLKIYDCLQEFKEKKLVPATPQAQVLSYEVVELLRETPTSPEIQELRQMLQAPHFKALLSAHDT
IAQKDFEPLLPPLPDNIPESEEAMRIVCLVKNQQPLGATIKRHEMTGDILVARIIHGGLAERSG
LLYAGDKLVEVNGVSVEGLDPEQVIHILAMSRGTIMFKVVPVSDPPVNSQKMVYVRAMTEYWPQ
EDPDIPCMDAGLPFQKGDILQIVDQNDALWWQARKISDPATCAGLVPSNHLLKRKQREFWWSQP
YQPHTCLKSTLSISMEEEDDMKIDEKCVEADEETFESEELSEDKEEFVGYGQKFFIAGFRRSMR
LCRRKSHLSPLHASVCCTGSCYSAVGAPYEEVVRYQRRPSDKYRLIVLMGPSGVGVNELRRQLI
EFNPSHFQSAVPHTTRTKKSYEMNGREYHYVSKETFESLIYSHRMLEYGEYKGHLYGTSVDAVQ
TVLVEGKICVMDLEPQDIQGVRTHELKPYVIFIKPSNMRCMKQSRKNAKIITDYYVDMKFKDED
LQEMENLAQRMETQFGQFFDHVIVNDSLHDACAQLLSAIQKAQEEPQWVPATWITSDTES

hide sequence

RefSeq Acc Id:

ENSPPAP00000025247 ⟸ ENSPPAT00000048074

RefSeq Acc Id:

ENSPPAP00000025249 ⟸ ENSPPAT00000048076

RefSeq Acc Id:

ENSPPAP00000025244 ⟸ ENSPPAT00000048071

RefSeq Acc Id:

ENSPPAP00000025246 ⟸ ENSPPAT00000048073

Protein Domains

Guanylate kinase-like L27 PDZ SH3

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000035730	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000025244	UniProtKB/TrEMBL
	ENSPPAP00000025246	UniProtKB/TrEMBL
	ENSPPAP00000025247	UniProtKB/TrEMBL
	ENSPPAP00000025249	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000048071	UniProtKB/TrEMBL
	ENSPPAT00000048073	UniProtKB/TrEMBL
	ENSPPAT00000048074	UniProtKB/TrEMBL
	ENSPPAT00000048076	UniProtKB/TrEMBL
Gene3D-CATH	2.30.42.10	UniProtKB/TrEMBL
InterPro	GK/Ca_channel_bsu	UniProtKB/TrEMBL
	Guanylate_kin-like_dom	UniProtKB/TrEMBL
	Guanylate_kinase_CS	UniProtKB/TrEMBL
	L27_C	UniProtKB/TrEMBL
	L27_dom	UniProtKB/TrEMBL
	L27_dom_sf	UniProtKB/TrEMBL
	MPP4_SH3	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
	SH3-like_dom_sf	UniProtKB/TrEMBL
	SH3_domain	UniProtKB/TrEMBL
NCBI Gene	MPP4	ENTREZGENE
Pfam	Guanylate_kin	UniProtKB/TrEMBL
	L27	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
PROSITE	GUANYLATE_KINASE_1	UniProtKB/TrEMBL
	GUANYLATE_KINASE_2	UniProtKB/TrEMBL
	L27	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
SMART	GuKc	UniProtKB/TrEMBL
	L27	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	SH3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF101288	UniProtKB/TrEMBL
	SSF50044	UniProtKB/TrEMBL
	SSF50156	UniProtKB/TrEMBL
	SSF52540	UniProtKB/TrEMBL
UniProt	A0A2R9B6P1_PANPA	UniProtKB/TrEMBL
	A0A2R9B850_PANPA	UniProtKB/TrEMBL
	A0A2R9BDT4_PANPA	UniProtKB/TrEMBL
	A0A2R9BDT9_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar