PLXNA4 (plexin A4) - Rat Genome Database

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Gene: PLXNA4 (plexin A4) Pan paniscus
Analyze
Symbol: PLXNA4
Name: plexin A4
RGD ID: 11690407
Description: ENCODES a protein that exhibits semaphorin receptor activity (inferred); INVOLVED IN anterior commissure morphogenesis (ortholog); axon guidance (ortholog); branchiomotor neuron axon guidance (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cerebellar climbing fiber to Purkinje cell synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: plexin-A4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26168,954,235 - 169,406,838 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1720,964,479 - 21,489,269 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07124,097,028 - 124,621,504 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17136,607,795 - 137,059,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7136,643,657 - 136,992,405 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLXNA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26168,954,235 - 169,406,838 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1720,964,479 - 21,489,269 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07124,097,028 - 124,621,504 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17136,607,795 - 137,059,706 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7136,643,657 - 136,992,405 (-)Ensemblpanpan1.1panPan2
PLXNA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387132,123,340 - 132,648,688 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7132,123,340 - 132,648,688 (-)EnsemblGRCh38hg38GRCh38
GRCh377131,808,099 - 132,333,447 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367131,458,631 - 131,983,987 (-)NCBINCBI36Build 36hg18NCBI36
Build 347131,269,944 - 131,370,450NCBI
Celera7126,560,410 - 127,085,672 (-)NCBICelera
Cytogenetic Map7q32.3NCBI
HuRef7126,124,398 - 126,649,403 (-)NCBIHuRef
CHM1_17131,743,547 - 132,268,963 (-)NCBICHM1_1
T2T-CHM13v2.07133,444,537 - 133,970,190 (-)NCBIT2T-CHM13v2.0
Plxna4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39632,121,478 - 32,565,127 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl632,121,203 - 32,565,127 (-)EnsemblGRCm39 Ensembl
GRCm38632,144,543 - 32,588,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl632,144,268 - 32,588,192 (-)EnsemblGRCm38mm10GRCm38
MGSCv37632,094,543 - 32,538,192 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36632,080,285 - 32,518,350 (-)NCBIMGSCv36mm8
Celera632,131,794 - 32,576,227 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map612.9NCBI
Plxna4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8461,687,483 - 62,129,467 (-)NCBIGRCr8
mRatBN7.2460,720,246 - 61,162,206 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl460,720,255 - 61,162,206 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx465,683,455 - 66,140,923 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0461,599,261 - 62,056,703 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0460,001,623 - 60,459,091 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0459,439,489 - 59,883,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl459,445,767 - 59,809,321 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0459,185,891 - 59,625,441 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4459,254,319 - 59,692,187 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1459,530,019 - 59,968,678 (-)NCBI
Celera455,807,378 - 56,248,398 (-)NCBICelera
Cytogenetic Map4q22NCBI
Plxna4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541035,281,648 - 35,713,453 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541035,281,042 - 35,714,094 (+)NCBIChiLan1.0ChiLan1.0
PLXNA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1144,683,569 - 5,110,113 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl144,680,882 - 5,103,050 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha144,344,388 - 4,770,614 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0144,419,335 - 4,847,251 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl144,421,153 - 4,842,617 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1144,622,751 - 5,050,482 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0144,368,126 - 4,795,816 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0144,510,104 - 4,938,016 (+)NCBIUU_Cfam_GSD_1.0
Plxna4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511822,892,653 - 23,318,229 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365793,092,924 - 3,444,012 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365793,025,251 - 3,449,347 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLXNA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1816,427,673 - 16,973,768 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11816,475,250 - 16,977,821 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PLXNA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121100,779,307 - 101,223,184 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21100,781,779 - 101,158,801 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660422,152,838 - 2,604,602 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plxna4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247833,658,835 - 4,285,638 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247833,831,320 - 4,292,594 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000044333   ⟹   ENSPPAP00000021530
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7136,643,657 - 136,992,405 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000044337   ⟹   ENSPPAP00000021534
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7136,968,534 - 136,992,405 (-)Ensembl
RefSeq Acc Id: XM_003813461   ⟹   XP_003813509
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26168,954,235 - 169,406,838 (-)NCBI
NHGRI_mPanPan1720,964,479 - 21,417,377 (-)NCBI
Mhudiblu_PPA_v07124,097,028 - 124,549,655 (-)NCBI
PanPan1.17136,607,795 - 137,059,706 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034965007   ⟹   XP_034820898
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26168,954,235 - 169,406,834 (-)NCBI
NHGRI_mPanPan1720,964,479 - 21,417,377 (-)NCBI
Mhudiblu_PPA_v07124,097,028 - 124,549,655 (-)NCBI
RefSeq Acc Id: XM_057302764   ⟹   XP_057158747
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26169,214,484 - 169,406,838 (-)NCBI
NHGRI_mPanPan1721,224,535 - 21,417,087 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003813509 (Get FASTA)   NCBI Sequence Viewer  
  XP_034820898 (Get FASTA)   NCBI Sequence Viewer  
  XP_057158747 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000021530.1
  ENSPPAP00000021534.1
Reference Protein Sequences
RefSeq Acc Id: XP_003813509   ⟸   XM_003813461
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B261 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034820898   ⟸   XM_034965007
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B261 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000021534   ⟸   ENSPPAT00000044337
RefSeq Acc Id: ENSPPAP00000021530   ⟸   ENSPPAT00000044333
RefSeq Acc Id: XP_057158747   ⟸   XM_057302764
- Peptide Label: isoform X2
Protein Domains
Sema


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000033968 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000044333.1 UniProtKB/TrEMBL
  ENSPPAT00000044337.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  Plexin UniProtKB/TrEMBL
  Plexin_cytoplasmic_RasGAP_dom UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  Plexin_repeat UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  TIG1_plexin UniProtKB/TrEMBL
  TIG2_plexin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene PLXNA4 ENTREZGENE
PANTHER PLEXIN-A4 UniProtKB/TrEMBL
  PTHR22625 UniProtKB/TrEMBL
Pfam Plexin_cytopl UniProtKB/TrEMBL
  Plexin_RBD UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
  TIG_2 UniProtKB/TrEMBL
  TIG_plexin UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART IPT UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  SSF101912 UniProtKB/TrEMBL
  SSF48350 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A2R9AWF1_PANPA UniProtKB/TrEMBL
  A0A2R9B261 ENTREZGENE, UniProtKB/TrEMBL