MTCL1 (microtubule crosslinking factor 1) - Rat Genome Database

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Gene: MTCL1 (microtubule crosslinking factor 1) Pan paniscus
Analyze
Symbol: MTCL1
Name: microtubule crosslinking factor 1
RGD ID: 11688298
Description: ENCODES a protein that exhibits microtubule binding (inferred); protein homodimerization activity (inferred); INVOLVED IN chromosome segregation (ortholog); positive regulation of protein targeting to membrane (ortholog); ASSOCIATED WITH autosomal dominant cerebellar ataxia (ortholog); cerebellar ataxia (ortholog); chromosome 18p deletion syndrome (ortholog); FOUND IN cytoskeleton (ortholog); kinetochore (ortholog); spindle microtubule (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: microtubule cross-linking factor 1; SOGA family member 2; SOGA2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21729,621,291 - 29,747,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1187,734,076 - 7,906,953 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl187,737,903 - 7,906,958 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MTCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21729,621,291 - 29,747,178 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1187,734,076 - 7,906,953 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl187,737,903 - 7,906,958 (-)Ensemblpanpan1.1panPan2
MTCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38188,705,556 - 8,832,778 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl188,705,556 - 8,832,778 (+)EnsemblGRCh38hg38GRCh38
GRCh37188,705,554 - 8,832,776 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36188,707,369 - 8,822,074 (+)NCBINCBI36Build 36hg18NCBI36
Celera188,601,536 - 8,716,876 (+)NCBICelera
Cytogenetic Map18p11.22NCBI
HuRef188,681,428 - 8,796,763 (+)NCBIHuRef
CHM1_1188,717,549 - 8,832,980 (+)NCBICHM1_1
T2T-CHM13v2.0188,868,615 - 8,995,758 (+)NCBIT2T-CHM13v2.0
Mtcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391766,643,975 - 66,760,672 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1766,643,977 - 66,756,745 (-)EnsemblGRCm39 Ensembl
GRCm381766,336,980 - 66,449,806 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1766,336,982 - 66,449,750 (-)EnsemblGRCm38mm10GRCm38
MGSCv371766,686,322 - 66,799,090 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361766,241,933 - 66,290,855 (-)NCBIMGSCv36mm8
Celera1770,637,666 - 70,750,457 (-)NCBICelera
Cytogenetic Map17E1.1NCBI
cM Map1735.3NCBI
Mtcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89113,722,138 - 113,888,413 (-)NCBIGRCr8
mRatBN7.29106,305,282 - 106,441,782 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9106,321,098 - 106,442,203 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.09114,493,901 - 114,632,632 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9114,491,419 - 114,619,711 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09113,981,913 - 114,136,747 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.49105,456,824 - 105,574,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.19105,636,246 - 105,783,556 (-)NCBI
Celera9103,496,748 - 103,614,716 (-)NCBICelera
Cytogenetic Map9q37NCBI
Mtcl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554022,979,547 - 3,076,283 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554022,980,539 - 3,076,283 (-)NCBIChiLan1.0ChiLan1.0
MTCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1774,840,271 - 74,967,849 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl774,840,032 - 74,967,305 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha774,230,206 - 74,358,609 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0774,890,596 - 75,019,099 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl774,890,596 - 75,019,104 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1774,592,893 - 74,721,307 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0774,611,401 - 74,739,900 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0774,917,008 - 75,045,339 (+)NCBIUU_Cfam_GSD_1.0
Mtcl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494471,873,016 - 72,002,758 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366702,388,908 - 2,516,875 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366702,388,839 - 2,516,758 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl699,062,354 - 99,178,468 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1699,062,347 - 99,178,570 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2692,351,813 - 92,452,978 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11867,666,982 - 67,792,792 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1867,667,690 - 67,788,981 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605042,606,815 - 42,732,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mtcl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477017,703,586 - 17,788,192 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477017,702,793 - 17,788,861 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046372   ⟹   ENSPPAP00000023547
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl187,737,903 - 7,906,958 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000046374   ⟹   ENSPPAP00000023549
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl187,737,903 - 7,896,118 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000046379   ⟹   ENSPPAP00000023554
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl187,770,472 - 7,783,189 (-)Ensembl
RefSeq Acc Id: XM_008961559   ⟹   XP_008959807
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
PanPan1.1187,734,076 - 7,906,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024926314   ⟹   XP_024782082
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
PanPan1.1187,734,076 - 7,906,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024926316   ⟹   XP_024782084
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,622,368 - 29,747,178 (-)NCBI
NHGRI_mPanPan11815,314,963 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
PanPan1.1187,734,076 - 7,906,698 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024926317   ⟹   XP_024782085
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,622,368 - 29,747,178 (-)NCBI
NHGRI_mPanPan11815,314,963 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
PanPan1.1187,734,076 - 7,906,953 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034943594   ⟹   XP_034799485
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
RefSeq Acc Id: XM_034943596   ⟹   XP_034799487
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
NHGRI_mPanPan11815,313,886 - 15,439,578 (-)NCBI
Mhudiblu_PPA_v0185,454,320 - 5,580,020 (-)NCBI
RefSeq Acc Id: XM_063597197   ⟹   XP_063453267
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
RefSeq Acc Id: XM_063597198   ⟹   XP_063453268
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,177 (-)NCBI
RefSeq Acc Id: XM_063597199   ⟹   XP_063453269
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,176 (-)NCBI
RefSeq Acc Id: XM_063597200   ⟹   XP_063453270
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,622,368 - 29,747,178 (-)NCBI
RefSeq Acc Id: XM_063597201   ⟹   XP_063453271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21729,621,291 - 29,747,177 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008959807   ⟸   XM_008961559
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024782085   ⟸   XM_024926317
- Peptide Label: isoform X11
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024782084   ⟸   XM_024926316
- Peptide Label: isoform X10
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024782082   ⟸   XM_024926314
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034799487   ⟸   XM_034943596
- Peptide Label: isoform X8
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034799485   ⟸   XM_034943594
- Peptide Label: isoform X6
- UniProtKB: A0A2R9B8F5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000023547   ⟸   ENSPPAT00000046372
RefSeq Acc Id: ENSPPAP00000023549   ⟸   ENSPPAT00000046374
RefSeq Acc Id: ENSPPAP00000023554   ⟸   ENSPPAT00000046379
RefSeq Acc Id: XP_063453271   ⟸   XM_063597201
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063453268   ⟸   XM_063597198
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063453269   ⟸   XM_063597199
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063453267   ⟸   XM_063597197
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063453270   ⟸   XM_063597200
- Peptide Label: isoform X7
Protein Domains
DUF4482


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034933 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046372.1 UniProtKB/TrEMBL
  ENSPPAT00000046374.1 UniProtKB/TrEMBL
  ENSPPAT00000046379.1 UniProtKB/TrEMBL
InterPro DUF4482 UniProtKB/TrEMBL
  SOGA UniProtKB/TrEMBL
NCBI Gene MTCL1 ENTREZGENE
PANTHER MICROTUBULE CROSS-LINKING FACTOR 1 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam DUF4482 UniProtKB/TrEMBL
  SOGA UniProtKB/TrEMBL
UniProt A0A2R9B3J0_PANPA UniProtKB/TrEMBL
  A0A2R9B3J5_PANPA UniProtKB/TrEMBL
  A0A2R9B8F5 ENTREZGENE, UniProtKB/TrEMBL