PARP11 (poly(ADP-ribose) polymerase family member 11) - Rat Genome Database

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Gene: PARP11 (poly(ADP-ribose) polymerase family member 11) Pan paniscus
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Symbol: PARP11
Name: poly(ADP-ribose) polymerase family member 11
RGD ID: 11686672
Description: ENCODES a protein that exhibits glycosyltransferase activity (inferred); NAD+ ADP-ribosyltransferase activity (inferred); NAD+-protein ADP-ribosyltransferase activity (inferred); INVOLVED IN nuclear envelope organization (ortholog); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; ASSOCIATED WITH genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN cytosol (inferred); nuclear body (inferred); nuclear envelope (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly [ADP-ribose] polymerase 11
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2109,361,911 - 9,423,559 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1129,328,236 - 9,420,322 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0123,928,474 - 3,992,713 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1123,854,338 - 3,916,318 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,857,256 - 3,879,242 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PARP11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2109,361,911 - 9,423,559 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1129,328,236 - 9,420,322 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0123,928,474 - 3,992,713 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1123,854,338 - 3,916,318 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl123,857,256 - 3,879,242 (-)Ensemblpanpan1.1panPan2
PARP11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38123,808,861 - 3,873,399 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl123,791,047 - 3,873,448 (-)EnsemblGRCh38hg38GRCh38
GRCh37123,918,027 - 3,982,565 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36123,788,288 - 3,852,863 (-)NCBINCBI36Build 36hg18NCBI36
Build 34123,791,397 - 3,852,801NCBI
Celera125,540,003 - 5,604,577 (-)NCBICelera
Cytogenetic Map12p13.32NCBI
HuRef123,774,077 - 3,838,651 (-)NCBIHuRef
CHM1_1123,917,467 - 3,982,056 (-)NCBICHM1_1
T2T-CHM13v2.0123,815,532 - 3,880,061 (-)NCBIT2T-CHM13v2.0
Parp11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396127,423,803 - 127,491,200 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6127,423,803 - 127,471,224 (+)EnsemblGRCm39 Ensembl
GRCm386127,446,830 - 127,514,233 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6127,446,840 - 127,494,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv376127,403,741 - 127,444,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366127,419,342 - 127,459,858 (+)NCBIMGSCv36mm8
Celera6129,128,692 - 129,169,408 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.39NCBI
Parp11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,984,192 - 162,030,550 (+)NCBIGRCr8
mRatBN7.24160,298,040 - 160,344,369 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4160,304,905 - 160,341,946 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.04160,013,968 - 160,059,981 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4160,020,472 - 160,058,729 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04231,551,302 - 231,590,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,866,313 - 163,937,904 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4149,016,105 - 149,058,242 (+)NCBICelera
Cytogenetic Map4q42NCBI
Parp11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554131,615,304 - 1,682,410 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554131,549,572 - 1,682,395 (-)NCBIChiLan1.0ChiLan1.0
PARP11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12740,982,462 - 41,029,264 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2740,943,824 - 41,026,800 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha275,652,608 - 5,699,370 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02741,340,525 - 41,387,051 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2741,299,505 - 41,387,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12741,277,910 - 41,324,618 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02741,252,812 - 41,299,595 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,014,976 - 5,061,763 (-)NCBIUU_Cfam_GSD_1.0
Parp11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945105,063,793 - 105,121,086 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366064,063,171 - 4,120,397 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366064,062,301 - 4,120,389 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARP11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl566,443,494 - 66,483,626 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1566,443,483 - 66,483,630 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2568,750,914 - 68,791,224 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARP11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1113,855,701 - 3,909,368 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl113,858,993 - 3,909,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660634,332,985 - 4,390,932 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parp11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860987,260 - 1,042,618 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860987,266 - 1,042,559 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000053490   ⟹   ENSPPAP00000030627
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl123,857,256 - 3,879,242 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000053495   ⟹   ENSPPAP00000030632
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl123,857,589 - 3,879,242 (-)Ensembl
RefSeq Acc Id: XM_003820343   ⟹   XP_003820391
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,559 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,420,322 (-)NCBI
Mhudiblu_PPA_v0123,931,076 - 3,992,713 (-)NCBI
PanPan1.1123,854,338 - 3,916,318 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014347075   ⟹   XP_014202561
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,342 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,420,100 (-)NCBI
Mhudiblu_PPA_v0123,931,076 - 3,992,713 (-)NCBI
PanPan1.1123,854,338 - 3,916,307 (-)NCBI
Sequence:
RefSeq Acc Id: XM_014347076   ⟹   XP_014202562
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,213 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,419,971 (-)NCBI
Mhudiblu_PPA_v0123,931,076 - 3,992,390 (-)NCBI
PanPan1.1123,854,338 - 3,915,963 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034935202   ⟹   XP_034791093
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,213 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,419,971 (-)NCBI
Mhudiblu_PPA_v0123,931,076 - 3,992,390 (-)NCBI
RefSeq Acc Id: XM_055095263   ⟹   XP_054951238
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,213 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,419,971 (-)NCBI
RefSeq Acc Id: XM_055095264   ⟹   XP_054951239
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,423,213 (-)NCBI
NHGRI_mPanPan1129,358,669 - 9,419,971 (-)NCBI
RefSeq Acc Id: XM_063593298   ⟹   XP_063449368
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2109,361,911 - 9,422,534 (-)NCBI
RefSeq Acc Id: XP_003820391   ⟸   XM_003820343
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BQC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014202561   ⟸   XM_014347075
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BQC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_014202562   ⟸   XM_014347076
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BQC9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034791093   ⟸   XM_034935202
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BQC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000030627   ⟸   ENSPPAT00000053490
RefSeq Acc Id: ENSPPAP00000030632   ⟸   ENSPPAT00000053495
RefSeq Acc Id: XP_054951239   ⟸   XM_055095264
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054951238   ⟸   XM_055095263
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063449368   ⟸   XM_063593298
- Peptide Label: isoform X2
Protein Domains
PARP catalytic   WWE


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038296 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000053490.1 UniProtKB/TrEMBL
  ENSPPAT00000053495.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.720.50 UniProtKB/TrEMBL
  3.90.228.10 UniProtKB/TrEMBL
InterPro Poly(ADP-ribose)pol_cat_dom UniProtKB/TrEMBL
  WWE-dom UniProtKB/TrEMBL
  WWE_dom_sf UniProtKB/TrEMBL
NCBI Gene PARP11 ENTREZGENE
PANTHER POLY [ADP-RIBOSE] POLYMERASE UniProtKB/TrEMBL
  PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP11 UniProtKB/TrEMBL
Pfam PARP UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
PROSITE PARP_CATALYTIC UniProtKB/TrEMBL
  WWE UniProtKB/TrEMBL
Superfamily-SCOP ADP-ribosylation UniProtKB/TrEMBL
  SSF117839 UniProtKB/TrEMBL
UniProt A0A2R9BQC4_PANPA UniProtKB/TrEMBL
  A0A2R9BQC9 ENTREZGENE, UniProtKB/TrEMBL