ABHD12 (abhydrolase domain containing 12, lysophospholipase) - Rat Genome Database

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Gene: ABHD12 (abhydrolase domain containing 12, lysophospholipase) Pan paniscus
Analyze
Symbol: ABHD12
Name: abhydrolase domain containing 12, lysophospholipase
RGD ID: 11685887
Description: ENCODES a protein that exhibits acylglycerol lipase activity (inferred); lysophospholipase activity (inferred); palmitoyl-(protein) hydrolase activity (inferred); INVOLVED IN adult walking behavior (ortholog); phosphatidylserine catabolic process (ortholog); response to auditory stimulus (ortholog); ASSOCIATED WITH cone dystrophy (ortholog); fundus dystrophy (ortholog); Hearing Loss (ortholog); FOUND IN AMPA glutamate receptor complex (inferred); cytoplasm (inferred); dendrite cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Also known as: abhydrolase domain containing 12; lysophosphatidylserine lipase ABHD12; monoacylglycerol lipase ABHD12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12025,644,824 - 25,741,073 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,645,046 - 25,740,943 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02025,239,710 - 25,335,941 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
ABHD12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12025,644,824 - 25,741,073 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2025,645,046 - 25,740,943 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02025,239,710 - 25,335,941 (-)NCBIMhudiblu_PPA_v0panPan3
ABHD12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2025,294,742 - 25,390,835 (-)EnsemblGRCh38hg38GRCh38
GRCh382025,294,743 - 25,390,835 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372025,275,379 - 25,371,471 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362025,223,379 - 25,319,477 (-)NCBINCBI36hg18NCBI36
Build 342025,223,379 - 25,319,454NCBI
Celera2025,349,117 - 25,445,220 (-)NCBI
Cytogenetic Map20p11.21NCBI
HuRef2025,232,725 - 25,328,525 (-)NCBIHuRef
CHM1_12025,276,265 - 25,320,544 (-)NCBICHM1_1
Abhd12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392150,674,413 - 150,746,705 (-)NCBIGRCm39mm39
GRCm39 Ensembl2150,674,413 - 150,746,661 (-)Ensembl
GRCm382150,832,493 - 150,904,779 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2150,832,493 - 150,904,741 (-)EnsemblGRCm38mm10GRCm38
MGSCv372150,658,251 - 150,730,467 (-)NCBIGRCm37mm9NCBIm37
MGSCv362150,523,934 - 150,534,011 (-)NCBImm8
Celera2152,065,897 - 152,137,905 (-)NCBICelera
Cytogenetic Map2G3NCBI
Abhd12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23139,659,315 - 139,719,529 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3139,659,317 - 139,719,564 (-)Ensembl
Rnor_6.03146,630,298 - 146,690,375 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3146,630,299 - 146,690,375 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03152,989,211 - 153,051,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,468,888 - 141,530,219 (-)NCBIRGSC3.4rn4RGSC3.4
Celera3138,421,060 - 138,481,137 (-)NCBICelera
Cytogenetic Map3q41NCBI
Abhd12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541531,284,947 - 31,337,160 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541531,284,947 - 31,337,703 (-)NCBIChiLan1.0ChiLan1.0
ABHD12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,496,183 - 1,562,738 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,496,551 - 1,562,688 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha231,525,725 - 1,592,232 (-)NCBI
ROS_Cfam_1.0231,736,578 - 1,803,088 (-)NCBI
ROS_Cfam_1.0 Ensembl231,736,578 - 1,803,125 (-)Ensembl
UMICH_Zoey_3.1231,577,308 - 1,643,795 (-)NCBI
UNSW_CanFamBas_1.0231,701,920 - 1,768,413 (-)NCBI
UU_Cfam_GSD_1.0231,669,411 - 1,735,944 (-)NCBI
Abhd12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640147,030,881 - 147,110,895 (+)NCBI
SpeTri2.0NW_004936620451,216 - 531,353 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1730,997,480 - 31,056,312 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11730,997,477 - 31,056,307 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ABHD12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_0236660787,726,486 - 7,748,675 (+)NCBIVero_WHO_p1.0
Abhd12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624939212,910 - 272,112 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054922   ⟹   ENSPPAP00000032056
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2025,645,046 - 25,740,913 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054932   ⟹   ENSPPAP00000032066
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2025,645,046 - 25,740,913 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054936   ⟹   ENSPPAP00000032070
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2025,648,693 - 25,740,943 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054948   ⟹   ENSPPAP00000032082
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2025,688,726 - 25,740,913 (-)Ensembl
RefSeq Acc Id: XM_034947592   ⟹   XP_034803483
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02025,239,710 - 25,335,941 (-)NCBI
RefSeq Acc Id: XM_034947593   ⟹   XP_034803484
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v02025,245,140 - 25,335,938 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034803483 (Get FASTA)   NCBI Sequence Viewer  
  XP_034803484 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034803483   ⟸   XM_034947592
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034803484   ⟸   XM_034947593
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000032056   ⟸   ENSPPAT00000054922
RefSeq Acc Id: ENSPPAP00000032066   ⟸   ENSPPAT00000054932
RefSeq Acc Id: ENSPPAP00000032070   ⟸   ENSPPAT00000054936
RefSeq Acc Id: ENSPPAP00000032082   ⟸   ENSPPAT00000054948
Protein Domains
Hydrolase_4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038923 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000032056 UniProtKB/TrEMBL
  ENSPPAP00000032066 UniProtKB/TrEMBL
  ENSPPAP00000032070 UniProtKB/TrEMBL
  ENSPPAP00000032082 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054922 UniProtKB/TrEMBL
  ENSPPAT00000054932 UniProtKB/TrEMBL
  ENSPPAT00000054936 UniProtKB/TrEMBL
  ENSPPAT00000054948 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  ABHD12 UniProtKB/TrEMBL
  Hydrolase_4 UniProtKB/TrEMBL
KEGG Report pps:100985803 UniProtKB/TrEMBL
NCBI Gene ABHD12 ENTREZGENE
PANTHER PTHR12277:SF61 UniProtKB/TrEMBL
Pfam Hydrolase_4 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9BQV1_PANPA UniProtKB/TrEMBL
  A0A2R9BQW3_PANPA UniProtKB/TrEMBL
  A0A2R9BQY8_PANPA UniProtKB/TrEMBL
  A0A2R9BRK6_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 ABHD12  abhydrolase domain containing 12, lysophospholipase  ABHD12  abhydrolase domain containing 12  Symbol and/or name change 5135510 APPROVED