NFU1 (NFU1 iron-sulfur cluster scaffold) - Rat Genome Database

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Gene: NFU1 (NFU1 iron-sulfur cluster scaffold) Pan paniscus
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Symbol: NFU1
Name: NFU1 iron-sulfur cluster scaffold
RGD ID: 11685336
Description: ENCODES a protein that exhibits 2 iron, 2 sulfur cluster binding (inferred); 4 iron, 4 sulfur cluster binding (inferred); iron ion binding (inferred); INVOLVED IN iron-sulfur cluster assembly (inferred); obsolete protein maturation by [2Fe-2S] cluster transfer (inferred); PARTICIPATES IN mitochondrial iron-sulfur cluster protein biogenesis pathway; ASSOCIATED WITH genetic disease (ortholog); multiple mitochondrial dysfunctions syndrome (ortholog); multiple mitochondrial dysfunctions syndrome 1 (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NFU1 iron-sulfur cluster scaffold homolog; NFU1 iron-sulfur cluster scaffold homolog, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,976,064 - 57,017,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,980,179 - 57,021,685 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,438,979 - 69,480,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A70,559,872 - 70,600,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,559,872 - 70,600,301 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
mitochondrion  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NFU1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21256,976,064 - 57,017,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A56,980,179 - 57,021,685 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A69,438,979 - 69,480,470 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A70,559,872 - 70,600,301 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A70,559,872 - 70,600,301 (-)Ensemblpanpan1.1panPan2
NFU1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38269,395,750 - 69,439,567 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl269,396,113 - 69,437,628 (-)EnsemblGRCh38hg38GRCh38
GRCh37269,622,882 - 69,666,699 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36269,476,756 - 69,518,257 (-)NCBINCBI36Build 36hg18NCBI36
Build 34269,534,905 - 69,576,404NCBI
Celera269,473,252 - 69,514,522 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef269,359,753 - 69,401,132 (-)NCBIHuRef
CHM1_1269,552,650 - 69,594,074 (-)NCBICHM1_1
T2T-CHM13v2.0269,408,096 - 69,451,867 (-)NCBIT2T-CHM13v2.0
Nfu1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,986,040 - 87,005,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,986,218 - 87,005,443 (+)EnsemblGRCm39 Ensembl
GRCm38687,009,234 - 87,028,461 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl687,009,236 - 87,028,461 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,959,830 - 86,978,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,975,538 - 86,994,049 (+)NCBIMGSCv36mm8
Celera688,949,192 - 88,967,878 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map637.76NCBI
Nfu1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84121,016,316 - 121,036,925 (+)NCBIGRCr8
mRatBN7.24119,458,981 - 119,480,162 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4119,459,061 - 119,480,373 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4124,932,395 - 124,952,928 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04120,707,135 - 120,727,667 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04119,331,386 - 119,351,919 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04118,814,284 - 118,834,955 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4118,814,284 - 118,834,955 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04183,383,769 - 183,404,239 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44121,184,017 - 121,187,110 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14121,401,604 - 121,432,159 (+)NCBI
Celera4108,428,818 - 108,449,350 (+)NCBICelera
Cytogenetic Map4q34NCBI
Nfu1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542415,647,623 - 15,674,573 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542415,648,213 - 15,671,383 (+)NCBIChiLan1.0ChiLan1.0
NFU1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,134,865 - 68,161,841 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1068,134,902 - 68,335,988 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1068,026,707 - 68,053,938 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01069,158,089 - 69,185,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1069,157,090 - 69,186,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11068,838,469 - 68,865,703 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01069,139,057 - 69,166,520 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01069,436,279 - 69,463,557 (-)NCBIUU_Cfam_GSD_1.0
Nfu1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629214,858,369 - 14,890,628 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649113,679,629 - 13,712,988 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649113,680,669 - 13,712,924 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFU1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,983,136 - 73,024,663 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1372,983,075 - 73,013,227 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2376,438,277 - 76,442,256 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NFU1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11437,690,329 - 37,731,093 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1437,690,656 - 37,730,819 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604574,263,441 - 74,305,552 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfu1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247623,887,124 - 3,917,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000047559   ⟹   ENSPPAP00000024734
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A70,559,872 - 70,600,301 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000047563   ⟹   ENSPPAP00000024738
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2A70,559,998 - 70,595,845 (-)Ensembl
RefSeq Acc Id: XM_003830928   ⟹   XP_003830976
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21256,976,064 - 57,017,749 (+)NCBI
NHGRI_mPanPan12A56,980,179 - 57,021,685 (+)NCBI
Mhudiblu_PPA_v02A69,438,979 - 69,480,467 (-)NCBI
PanPan1.12A70,559,872 - 70,600,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008956341   ⟹   XP_008954589
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21256,976,488 - 57,017,749 (+)NCBI
NHGRI_mPanPan12A56,980,426 - 57,021,685 (+)NCBI
Mhudiblu_PPA_v02A69,438,979 - 69,480,470 (-)NCBI
PanPan1.12A70,559,872 - 70,600,301 (-)NCBI
Sequence:
RefSeq Acc Id: XM_024927759   ⟹   XP_024783527
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21256,976,453 - 57,017,749 (+)NCBI
NHGRI_mPanPan12A56,980,517 - 57,021,685 (+)NCBI
Mhudiblu_PPA_v02A69,438,979 - 69,480,079 (-)NCBI
PanPan1.12A70,559,878 - 70,599,909 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003830976 (Get FASTA)   NCBI Sequence Viewer  
  XP_008954589 (Get FASTA)   NCBI Sequence Viewer  
  XP_024783527 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024734.1
  ENSPPAP00000024738.1
RefSeq Acc Id: XP_008954589   ⟸   XM_008956341
- Peptide Label: isoform X3
- UniProtKB: A0A2R9B582 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003830976   ⟸   XM_003830928
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B582 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024783527   ⟸   XM_024927759
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B582 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000024734   ⟸   ENSPPAT00000047559
Ensembl Acc Id: ENSPPAP00000024738   ⟸   ENSPPAT00000047563

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035496 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047559.1 UniProtKB/TrEMBL
  ENSPPAT00000047563.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.70 UniProtKB/TrEMBL
  3.30.300.130 UniProtKB/TrEMBL
InterPro FSCA_dom_sf UniProtKB/TrEMBL
  Nfu/NifU_N UniProtKB/TrEMBL
  Nfu/NifU_N_sf UniProtKB/TrEMBL
  NFU1-like UniProtKB/TrEMBL
  NIF_FeS_clus_asmbl_NifU_C UniProtKB/TrEMBL
NCBI Gene NFU1 ENTREZGENE
PANTHER IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED UniProtKB/TrEMBL
  NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Nfu_N UniProtKB/TrEMBL
  NifU UniProtKB/TrEMBL
PIRSF HIRIP5 UniProtKB/TrEMBL
SMART Nfu_N UniProtKB/TrEMBL
Superfamily-SCOP SSF110836 UniProtKB/TrEMBL
  SSF117916 UniProtKB/TrEMBL
UniProt A0A2R9B582 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BC51_PANPA UniProtKB/TrEMBL