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Gene: CYP46A1 (cytochrome P450 family 46 subfamily A member 1) Pan paniscus
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Symbol: CYP46A1
Name: cytochrome P450 family 46 subfamily A member 1
Description: ENCODES a protein that exhibits cholesterol 24-hydroxylase activity (ortholog); heme binding (ortholog); iron ion binding (ortholog); INVOLVED IN bile acid biosynthetic process (ortholog); cholesterol catabolic process (ortholog); nervous system development (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); FOUND IN dendrite (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cholesterol 24-hydroxylase; LOC100978372
Orthologs:
Homo sapiens (human) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cyp46a1 (cytochrome P450, family 46, subfamily a, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102030124 (cholesterol 24-hydroxylase)
Canis lupus familiaris (dog) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101961079 (cholesterol 24-hydroxylase)
Sus scrofa (pig) : LOC100512793 (cholesterol 24-hydroxylase)
Chlorocebus sabaeus (African green monkey) : CYP46A1 (cytochrome P450 family 46 subfamily A member 1)
Heterocephalus glaber (naked mole-rat) : LOC101708822 (cholesterol 24-hydroxylase)
more info ...
Latest Assembly: PanPan1.1 - Bonobo PanPan1.1 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1 Ensembl1499,628,511 - 99,671,218 (+)Ensemblpanpan1.1panPan2
PanPan1.11499,628,511 - 99,671,218 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
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Comparative Map Data

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Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

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Nomenclature History
 
More on CYP46A1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11683512
Created: 2017-01-20
Species: Pan paniscus
Last Modified: 2020-02-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.