RGMB (repulsive guidance molecule BMP co-receptor b) - Rat Genome Database

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Gene: RGMB (repulsive guidance molecule BMP co-receptor b) Pan paniscus
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Symbol: RGMB
Name: repulsive guidance molecule BMP co-receptor b
RGD ID: 11678494
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN BMP signaling pathway (ortholog); cell adhesion (ortholog); positive regulation of DNA-templated transcription (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN endoplasmic reticulum-Golgi intermediate compartment (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: repulsive guidance molecule B; repulsive guidance molecule family member b; RGM domain family member B; RGM domain family, member B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2494,018,500 - 94,047,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1592,173,524 - 92,200,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0594,080,200 - 94,107,441 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1599,639,059 - 99,661,904 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl599,639,527 - 99,661,904 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
RGMB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2494,018,500 - 94,047,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1592,173,524 - 92,200,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0594,080,200 - 94,107,441 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1599,639,059 - 99,661,904 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl599,639,527 - 99,661,904 (+)Ensemblpanpan1.1panPan2
RGMB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38598,768,632 - 98,796,494 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl598,768,650 - 98,798,643 (+)EnsemblGRCh38hg38GRCh38
GRCh37598,104,336 - 98,132,198 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36598,132,900 - 98,160,098 (+)NCBINCBI36Build 36hg18NCBI36
Build 34598,132,899 - 98,144,789NCBI
Celera593,989,124 - 94,016,323 (+)NCBICelera
Cytogenetic Map5q15NCBI
HuRef593,292,769 - 93,319,901 (+)NCBIHuRef
CHM1_1597,537,613 - 97,564,811 (+)NCBICHM1_1
T2T-CHM13v2.0599,271,925 - 99,299,789 (+)NCBIT2T-CHM13v2.0
Rgmb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391716,024,923 - 16,051,508 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1716,023,450 - 16,051,301 (-)EnsemblGRCm39 Ensembl
GRCm381715,804,661 - 15,831,246 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1715,803,188 - 15,831,039 (-)EnsemblGRCm38mm10GRCm38
MGSCv371715,943,217 - 15,963,550 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361715,510,943 - 15,531,276 (-)NCBIMGSCv36mm8
Celera1716,596,701 - 16,617,053 (-)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.96NCBI
Rgmb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,439,748 - 65,465,149 (-)NCBIGRCr8
mRatBN7.2156,766,598 - 56,792,396 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl156,767,850 - 56,792,425 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0157,794,046 - 57,819,941 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl157,796,709 - 57,815,038 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0158,721,193 - 58,746,618 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera152,968,047 - 52,993,851 (-)NCBICelera
Cytogenetic Map1q12NCBI
Rgmb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541814,308,392 - 14,326,762 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541814,305,634 - 14,321,804 (-)NCBIChiLan1.0ChiLan1.0
RGMB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1311,407,426 - 11,427,317 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha312,744,584 - 12,769,074 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0311,292,540 - 11,317,334 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1311,242,095 - 11,266,567 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0311,248,952 - 11,273,665 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0311,450,625 - 11,475,348 (-)NCBIUU_Cfam_GSD_1.0
Rgmb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213166,865,191 - 166,893,385 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365235,050,377 - 5,078,866 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365235,050,765 - 5,078,777 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGMB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2105,042,532 - 105,070,409 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12105,042,479 - 105,070,428 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22108,897,113 - 108,924,614 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGMB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1232,339,567 - 2,368,239 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl232,341,856 - 2,369,294 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,119,736 - 12,147,699 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgmb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474317,232,391 - 17,251,500 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474317,228,382 - 17,254,184 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000019990   ⟹   ENSPPAP00000004337
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl599,639,527 - 99,661,904 (+)Ensembl
RefSeq Acc Id: XM_034960289   ⟹   XP_034816180
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2494,018,500 - 94,047,346 (+)NCBI
NHGRI_mPanPan1592,173,524 - 92,200,986 (+)NCBI
Mhudiblu_PPA_v0594,080,200 - 94,107,441 (+)NCBI
RefSeq Acc Id: XM_034960290   ⟹   XP_034816181
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2494,020,243 - 94,047,346 (+)NCBI
NHGRI_mPanPan1592,173,928 - 92,200,986 (+)NCBI
Mhudiblu_PPA_v0594,080,226 - 94,107,441 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034816180 (Get FASTA)   NCBI Sequence Viewer  
  XP_034816181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004337.1
Reference Protein Sequences
RefSeq Acc Id: XP_034816180   ⟸   XM_034960289
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034816181   ⟸   XM_034960290
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZKD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000004337   ⟸   ENSPPAT00000019990
Protein Domains
Repulsive guidance molecule C-terminal   Repulsive guidance molecule N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000018256 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000019990.1 UniProtKB/TrEMBL
Gene3D-CATH Mog1/PsbP, alpha/beta/alpha sandwich UniProtKB/TrEMBL
InterPro RGM UniProtKB/TrEMBL
  RGM_C UniProtKB/TrEMBL
  RGM_N UniProtKB/TrEMBL
NCBI Gene RGMB ENTREZGENE
PANTHER PTHR31428 UniProtKB/TrEMBL
  PTHR31428:SF5 UniProtKB/TrEMBL
Pfam RGM_C UniProtKB/TrEMBL
  RGM_N UniProtKB/TrEMBL
UniProt A0A2R8ZKD7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-01-16 RGMB  repulsive guidance molecule BMP co-receptor b    repulsive guidance molecule family member b  Symbol and/or name change 5135510 APPROVED