LSM14A (LSM14A mRNA processing body assembly factor) - Rat Genome Database

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Gene: LSM14A (LSM14A mRNA processing body assembly factor) Pan paniscus
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Symbol: LSM14A
Name: LSM14A mRNA processing body assembly factor
RGD ID: 11676051
Description: ENCODES a protein that exhibits double-stranded DNA binding (ortholog); double-stranded RNA binding (ortholog); single-stranded RNA binding (ortholog); INVOLVED IN defense response to virus (ortholog); mitotic spindle assembly (ortholog); negative regulation of translation (ortholog); ASSOCIATED WITH genetic disease (ortholog); hereditary spastic paraplegia 75 (ortholog); FOUND IN cytoplasmic ribonucleoprotein granule (ortholog); cytoplasmic stress granule (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LSM14A, mRNA processing body assembly factor; LSM14A, SCD6 homolog A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22040,148,647 - 40,208,181 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11942,148,734 - 42,209,496 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01931,099,211 - 31,159,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11939,831,117 - 39,891,803 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1939,831,117 - 39,891,794 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LSM14A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22040,148,647 - 40,208,181 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11942,148,734 - 42,209,496 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01931,099,211 - 31,159,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11939,831,117 - 39,891,803 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1939,831,117 - 39,891,794 (+)Ensemblpanpan1.1panPan2
LSM14A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381934,172,504 - 34,229,288 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1934,172,504 - 34,229,288 (+)EnsemblGRCh38hg38GRCh38
GRCh371934,663,409 - 34,720,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361939,355,311 - 39,412,048 (+)NCBINCBI36Build 36hg18NCBI36
Build 341939,355,310 - 39,412,048NCBI
Celera1931,356,940 - 31,413,990 (+)NCBICelera
Cytogenetic Map19q13.11NCBI
HuRef1931,161,966 - 31,218,694 (+)NCBIHuRef
CHM1_11934,664,818 - 34,721,879 (+)NCBICHM1_1
T2T-CHM13v2.01936,693,004 - 36,749,747 (+)NCBIT2T-CHM13v2.0
Lsm14a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,043,569 - 34,089,134 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl734,044,071 - 34,092,740 (-)EnsemblGRCm39 Ensembl
GRCm38734,344,144 - 34,390,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl734,344,646 - 34,393,315 (-)EnsemblGRCm38mm10GRCm38
MGSCv37735,129,738 - 35,174,559 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36734,053,479 - 34,098,300 (-)NCBIMGSCv36mm8
Celera729,486,917 - 29,531,984 (-)NCBICelera
Cytogenetic Map7B1NCBI
cM Map719.56NCBI
Lsm14a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8196,101,990 - 96,146,578 (-)NCBIGRCr8
mRatBN7.2186,964,800 - 87,009,325 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,964,828 - 87,009,276 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx192,369,445 - 92,413,687 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,835,447 - 100,879,687 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0194,127,754 - 94,171,995 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0190,200,866 - 90,246,292 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl190,200,876 - 90,246,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0191,343,456 - 91,388,668 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,795,681 - 86,840,006 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1186,873,519 - 86,918,182 (-)NCBI
Celera181,331,024 - 81,360,652 (-)NCBICelera
Cytogenetic Map1q21NCBI
Lsm14a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554683,799,897 - 3,863,241 (+)NCBIChiLan1.0ChiLan1.0
LSM14A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11118,061,854 - 118,117,493 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1118,063,512 - 118,117,478 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1117,459,811 - 117,515,443 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01118,657,288 - 118,712,897 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1118,657,278 - 118,713,094 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11118,218,375 - 118,273,952 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,844,503 - 117,900,061 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,903,023 - 118,958,439 (-)NCBIUU_Cfam_GSD_1.0
Lsm14a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093499,854,141 - 9,921,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365701,729,841 - 1,791,778 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365701,723,966 - 1,791,784 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LSM14A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl643,847,732 - 43,903,587 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1643,847,882 - 43,901,697 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2639,316,239 - 39,340,790 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LSM14A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1629,211,582 - 29,266,793 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl629,211,785 - 29,266,981 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660736,982,252 - 7,042,034 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lsm14a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247948,913,278 - 9,035,652 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000062994   ⟹   ENSPPAP00000040081
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,117 - 39,891,794 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062999   ⟹   ENSPPAP00000040086
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,117 - 39,891,794 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063018   ⟹   ENSPPAP00000040105
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,215 - 39,888,958 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063028   ⟹   ENSPPAP00000040115
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,215 - 39,888,833 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063035   ⟹   ENSPPAP00000040122
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,215 - 39,888,833 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063055   ⟹   ENSPPAP00000040141
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,215 - 39,884,414 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000063056   ⟹   ENSPPAP00000040142
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1939,831,215 - 39,884,414 (+)Ensembl
RefSeq Acc Id: XM_003816189   ⟹   XP_003816237
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22040,148,647 - 40,208,181 (+)NCBI
NHGRI_mPanPan11942,148,734 - 42,209,496 (+)NCBI
Mhudiblu_PPA_v01931,099,211 - 31,159,930 (+)NCBI
PanPan1.11939,831,117 - 39,891,803 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003816190   ⟹   XP_003816238
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22040,148,647 - 40,207,519 (+)NCBI
NHGRI_mPanPan11942,148,746 - 42,209,496 (+)NCBI
Mhudiblu_PPA_v01931,099,261 - 31,159,930 (+)NCBI
PanPan1.11939,831,117 - 39,891,803 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034946474   ⟹   XP_034802365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22040,148,647 - 40,208,181 (+)NCBI
NHGRI_mPanPan11942,148,737 - 42,209,496 (+)NCBI
Mhudiblu_PPA_v01931,099,261 - 31,159,930 (+)NCBI
RefSeq Acc Id: XM_055104180   ⟹   XP_054960155
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22040,148,647 - 40,207,520 (+)NCBI
NHGRI_mPanPan11942,148,746 - 42,209,496 (+)NCBI
RefSeq Acc Id: XP_003816238   ⟸   XM_003816190
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CDQ6 (UniProtKB/TrEMBL),   A0A2R9CDU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816237   ⟸   XM_003816189
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CDR2 (UniProtKB/TrEMBL),   A0A2R9CDU8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034802365   ⟸   XM_034946474
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CP42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960155   ⟸   XM_055104180
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CP42 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000040086   ⟸   ENSPPAT00000062999
RefSeq Acc Id: ENSPPAP00000040115   ⟸   ENSPPAT00000063028
RefSeq Acc Id: ENSPPAP00000040105   ⟸   ENSPPAT00000063018
RefSeq Acc Id: ENSPPAP00000040141   ⟸   ENSPPAT00000063055
RefSeq Acc Id: ENSPPAP00000040081   ⟸   ENSPPAT00000062994
RefSeq Acc Id: ENSPPAP00000040142   ⟸   ENSPPAT00000063056
RefSeq Acc Id: ENSPPAP00000040122   ⟸   ENSPPAT00000063035
Protein Domains
DFDF   FFD box profile   Sm   TFG box profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042618 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062994.1 UniProtKB/TrEMBL
  ENSPPAT00000062999.1 UniProtKB/TrEMBL
  ENSPPAT00000063018.1 UniProtKB/TrEMBL
  ENSPPAT00000063028.1 UniProtKB/TrEMBL
  ENSPPAT00000063035.1 UniProtKB/TrEMBL
  ENSPPAT00000063055.1 UniProtKB/TrEMBL
  ENSPPAT00000063056.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.100 UniProtKB/TrEMBL
InterPro DFDF UniProtKB/TrEMBL
  FDF_dom UniProtKB/TrEMBL
  FFD_box UniProtKB/TrEMBL
  IPR047575 UniProtKB/TrEMBL
  Lsm14-like_N UniProtKB/TrEMBL
  LSM_dom_sf UniProtKB/TrEMBL
  TFG_box UniProtKB/TrEMBL
KEGG Report pps:100986218 UniProtKB/TrEMBL
NCBI Gene LSM14A ENTREZGENE
PANTHER PROTEIN LSM14 HOMOLOG A UniProtKB/TrEMBL
  SCD6 PROTEIN-RELATED UniProtKB/TrEMBL
Pfam FDF UniProtKB/TrEMBL
  LSM14 UniProtKB/TrEMBL
PROSITE DFDF UniProtKB/TrEMBL
  FFD UniProtKB/TrEMBL
  PS52002 UniProtKB/TrEMBL
  TFG UniProtKB/TrEMBL
SMART FDF UniProtKB/TrEMBL
  LSM14 UniProtKB/TrEMBL
Superfamily-SCOP SSF50182 UniProtKB/TrEMBL
UniProt A0A2R9CDQ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CDR2 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CDT6_PANPA UniProtKB/TrEMBL
  A0A2R9CDU8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CDX1_PANPA UniProtKB/TrEMBL
  A0A2R9CP42 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CP56_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 LSM14A  LSM14A mRNA processing body assembly factor    LSM14A, mRNA processing body assembly factor  Symbol and/or name change 5135510 APPROVED