ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1) - Rat Genome Database
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Gene: ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1) Pan paniscus
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Symbol: ATP1A1
Name: ATPase Na+/K+ transporting subunit alpha 1
RGD ID: 11673448
Description: ENCODES a protein that exhibits ADP binding (ortholog); ankyrin binding (ortholog); ATP binding (ortholog); INVOLVED IN cellular potassium ion homeostasis (ortholog); cellular response to mechanical stimulus (ortholog); cellular response to steroid hormone stimulus (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH adenoma (ortholog); adrenal cortical adenoma (ortholog); Charcot-Marie-Tooth disease type 2DD (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: sodium/potassium-transporting ATPase subunit alpha-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11121,212,161 - 121,232,876 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1121,212,488 - 121,243,099 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0186,162,401 - 86,193,883 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiloride pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
bendroflumethiazide pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bumetanide pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
chlorothiazide pharmacodynamics pathway  (ISO)
chlorthalidone pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
cystinuria pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
eplerenone pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
etacrynic acid pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
furosemide pharmacodynamics pathway  (ISO)
Hartnup disease pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrochlorothiazide pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydroflumethiazide pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
iminoglycinuria pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
lactose degradation pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
lysinuric protein intolerance pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metolazone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
spironolactone pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
torasemide pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
trehalose degradation pathway  (ISO)
triamterene pharmacodynamics pathway  (ISO)
trichlormethiazide pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
ATP1A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11121,212,161 - 121,232,876 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1121,212,488 - 121,243,099 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0186,162,401 - 86,193,883 (-)NCBIMhudiblu_PPA_v0panPan3
ATP1A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1116,372,668 - 116,410,261 (+)EnsemblGRCh38hg38GRCh38
GRCh381116,372,986 - 116,410,259 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371116,915,866 - 116,947,396 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361116,717,359 - 116,748,919 (+)NCBINCBI36hg18NCBI36
Build 341116,627,877 - 116,659,436NCBI
Celera1115,144,421 - 115,176,022 (+)NCBI
Cytogenetic Map1p13.1NCBI
HuRef1114,773,961 - 114,805,562 (+)NCBIHuRef
CHM1_11117,030,620 - 117,062,221 (+)NCBICHM1_1
Atp1a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393101,483,535 - 101,512,023 (-)NCBIGRCm39mm39
GRCm39 Ensembl3101,483,535 - 101,512,000 (-)Ensembl
GRCm383101,576,219 - 101,604,707 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3101,576,219 - 101,604,684 (-)EnsemblGRCm38mm10GRCm38
MGSCv373101,380,146 - 101,408,580 (-)NCBIGRCm37mm9NCBIm37
MGSCv363101,705,284 - 101,733,721 (-)NCBImm8
Celera3103,788,093 - 103,816,528 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map344.3NCBI
Atp1a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22189,020,722 - 189,048,826 (-)NCBI
Rnor_6.0 Ensembl2204,003,742 - 204,032,023 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02204,003,742 - 204,032,023 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02223,440,514 - 223,469,880 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42196,657,749 - 196,687,242 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12196,620,502 - 196,649,996 (-)NCBI
Celera2181,455,492 - 181,483,650 (-)NCBICelera
Cytogenetic Map2q34NCBI
Atp1a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543519,536,634 - 19,564,580 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543519,537,224 - 19,563,631 (+)NCBIChiLan1.0ChiLan1.0
ATP1A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1753,813,976 - 53,847,167 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11753,828,482 - 53,847,043 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Atp1a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366271,555,151 - 1,584,370 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP1A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4104,353,506 - 104,384,606 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14104,353,506 - 104,384,321 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24114,431,993 - 114,451,892 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap4q1.6-q2.3NCBI
ATP1A1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12017,319,440 - 17,351,054 (-)NCBI
ChlSab1.1 Ensembl2017,315,117 - 17,351,054 (-)Ensembl
Atp1a1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477212,099,523 - 12,127,437 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034929861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000057170   ⟹   ENSPPAP00000034289
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1121,212,488 - 121,243,099 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057188   ⟹   ENSPPAP00000034307
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1121,212,488 - 121,233,755 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057191   ⟹   ENSPPAP00000034310
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1121,212,488 - 121,233,556 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057198   ⟹   ENSPPAP00000034317
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1121,212,488 - 121,232,894 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057205   ⟹   ENSPPAP00000034324
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1121,215,099 - 121,232,863 (-)Ensembl
RefSeq Acc Id: XM_034929861   ⟹   XP_034785752
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0186,162,401 - 86,193,883 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034785752 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034785752   ⟸   XM_034929861
RefSeq Acc Id: ENSPPAP00000034289   ⟸   ENSPPAT00000057170
RefSeq Acc Id: ENSPPAP00000034307   ⟸   ENSPPAT00000057188
RefSeq Acc Id: ENSPPAP00000034317   ⟸   ENSPPAT00000057198
RefSeq Acc Id: ENSPPAP00000034310   ⟸   ENSPPAT00000057191
RefSeq Acc Id: ENSPPAP00000034324   ⟸   ENSPPAT00000057205
Protein Domains
Cation_ATPase_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039938 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000034289 UniProtKB/TrEMBL
  ENSPPAP00000034307 UniProtKB/TrEMBL
  ENSPPAP00000034310 UniProtKB/TrEMBL
  ENSPPAP00000034317 UniProtKB/TrEMBL
  ENSPPAP00000034324 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057170 UniProtKB/TrEMBL
  ENSPPAT00000057188 UniProtKB/TrEMBL
  ENSPPAT00000057191 UniProtKB/TrEMBL
  ENSPPAT00000057198 UniProtKB/TrEMBL
  ENSPPAT00000057205 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1110.10 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
InterPro ATPase_P-typ_cation-transptr_C UniProtKB/TrEMBL
  ATPase_P-typ_cation-transptr_N UniProtKB/TrEMBL
  ATPase_P-typ_cyto_dom_N UniProtKB/TrEMBL
  ATPase_P-typ_P_site UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom_sf UniProtKB/TrEMBL
  ATPase_P-typ_transduc_dom_A_sf UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  P-type_ATPase_IIC UniProtKB/TrEMBL
  P_typ_ATPase UniProtKB/TrEMBL
NCBI Gene ATP1A1 ENTREZGENE
Pfam Cation_ATPase_C UniProtKB/TrEMBL
  Cation_ATPase_N UniProtKB/TrEMBL
PROSITE ATPASE_E1_E2 UniProtKB/TrEMBL
SMART Cation_ATPase_N UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
  SSF81653 UniProtKB/TrEMBL
  SSF81660 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
TIGRFAMs ATPase-IIC_X-K UniProtKB/TrEMBL
  ATPase_P-type UniProtKB/TrEMBL
UniProt A0A2R9BX94_PANPA UniProtKB/TrEMBL
  A0A2R9BXA3_PANPA UniProtKB/TrEMBL
  A0A2R9C0M5_PANPA UniProtKB/TrEMBL
  A0A2R9C6X8_PANPA UniProtKB/TrEMBL
  A0A2R9C713_PANPA UniProtKB/TrEMBL