CRPPA (CDP-L-ribitol pyrophosphorylase A) - Rat Genome Database
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Gene: CRPPA (CDP-L-ribitol pyrophosphorylase A) Pan paniscus
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Symbol: CRPPA
Name: CDP-L-ribitol pyrophosphorylase A
RGD ID: 11669627
Description: ENCODES a protein that exhibits cytidylyltransferase activity (ortholog); D-ribitol-5-phosphate cytidylyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN axon guidance (ortholog); protein glycosylation (ortholog); protein O-linked mannosylation (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2U (ortholog); congenital muscular dystrophy (ortholog); congenital muscular dystrophy due to integrin alpha-7 deficiency (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: D-ribitol-5-phosphate cytidylyltransferase; isoprenoid synthase domain containing; ISPD
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1716,076,235 - 16,405,268 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,077,091 - 16,405,220 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0716,747,569 - 17,078,389 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
CRPPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1716,076,235 - 16,405,268 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl716,077,091 - 16,405,220 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0716,747,569 - 17,078,389 (-)NCBIMhudiblu_PPA_v0panPan3
CRPPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl716,087,525 - 16,421,538 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl716,087,525 - 16,502,504 (-)EnsemblGRCh38hg38GRCh38
GRCh38716,087,525 - 16,421,538 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37716,127,150 - 16,461,163 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36716,097,786 - 16,427,472 (-)NCBINCBI36hg18NCBI36
Celera716,106,872 - 16,440,699 (-)NCBI
Cytogenetic Map7p21.2NCBI
HuRef716,012,324 - 16,347,484 (-)NCBIHuRef
CHM1_1716,126,841 - 16,460,716 (-)NCBICHM1_1
CRA_TCAGchr7v2716,180,240 - 16,514,081 (-)NCBI
Crppa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391236,430,334 - 36,739,502 (+)NCBIGRCm39mm39
GRCm39 Ensembl1236,431,449 - 36,739,502 (+)Ensembl
GRCm381236,380,575 - 36,689,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1236,381,450 - 36,689,503 (+)EnsemblGRCm38mm10GRCm38
MGSCv371237,108,106 - 37,416,031 (+)NCBIGRCm37mm9NCBIm37
MGSCv361236,891,849 - 37,015,131 (+)NCBImm8
Celera1237,825,234 - 38,127,522 (+)NCBICelera
Cytogenetic Map12A3NCBI
Crppa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2653,120,264 - 53,397,030 (+)NCBI
Rnor_6.0 Ensembl655,881,387 - 56,159,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0655,880,136 - 56,159,466 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0665,490,939 - 65,818,620 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4655,139,155 - 55,419,630 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1655,421,454 - 55,422,754 (+)NCBI
Celera652,259,290 - 52,534,570 (+)NCBICelera
Cytogenetic Map6q16-q21NCBI
Crppa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541019,359,868 - 19,614,344 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541019,359,495 - 19,614,283 (-)NCBIChiLan1.0ChiLan1.0
CRPPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1430,648,128 - 30,989,604 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11430,697,060 - 30,989,423 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Crppa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365462,658,195 - 2,945,542 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRPPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl985,415,550 - 85,710,752 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1985,419,401 - 85,711,146 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2994,460,506 - 94,549,186 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRPPA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12141,691,771 - 42,008,484 (+)NCBI
ChlSab1.1 Ensembl2141,691,912 - 42,010,301 (+)Ensembl
Crppa
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473913,813,779 - 14,114,296 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000045245   ⟹   ENSPPAP00000022435
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,077,091 - 16,405,220 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000045247   ⟹   ENSPPAP00000022437
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl716,077,091 - 16,405,220 (-)Ensembl
RefSeq Acc Id: XM_003825009   ⟹   XP_003825057
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1716,076,235 - 16,405,268 (-)NCBI
Mhudiblu_PPA_v0716,747,569 - 17,078,389 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008978703   ⟹   XP_008976951
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1716,076,235 - 16,405,268 (-)NCBI
Mhudiblu_PPA_v0716,747,569 - 17,078,389 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034963741   ⟹   XP_034819632
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0716,902,940 - 17,078,389 (-)NCBI
RefSeq Acc Id: XM_034963742   ⟹   XP_034819633
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0716,747,569 - 17,078,389 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003825057 (Get FASTA)   NCBI Sequence Viewer  
  XP_008976951 (Get FASTA)   NCBI Sequence Viewer  
  XP_034819632 (Get FASTA)   NCBI Sequence Viewer  
  XP_034819633 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008976951   ⟸   XM_008978703
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003825057   ⟸   XM_003825009
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034819633   ⟸   XM_034963742
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034819632   ⟸   XM_034963741
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000022437   ⟸   ENSPPAT00000045247
RefSeq Acc Id: ENSPPAP00000022435   ⟸   ENSPPAT00000045245
Protein Domains
ISPD_C


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022435 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAP00000022437 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045245 UniProtKB/TrEMBL
  ENSPPAT00000045247 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/TrEMBL
InterPro IspD/TarI UniProtKB/TrEMBL
  ISPD_C UniProtKB/TrEMBL
  ISPD_synthase_CS UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
KEGG Report pps:100989529 UniProtKB/TrEMBL
NCBI Gene ISPD ENTREZGENE
Pfam IspD UniProtKB/TrEMBL
  ISPD_C UniProtKB/TrEMBL
PROSITE ISPD UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt A0A2R9AYY5_PANPA UniProtKB/TrEMBL
  A0A2R9B2Q5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-15 CRPPA  CDP-L-ribitol pyrophosphorylase A  ISPD  isoprenoid synthase domain containing  Symbol and/or name change 5135510 APPROVED