SCFD1 (sec1 family domain containing 1) - Rat Genome Database

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Gene: SCFD1 (sec1 family domain containing 1) Pan paniscus
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Symbol: SCFD1
Name: sec1 family domain containing 1
RGD ID: 11669249
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); syntaxin binding (ortholog); INVOLVED IN post-Golgi vesicle-mediated transport (ortholog); regulation of ER to Golgi vesicle-mediated transport (ortholog); response to hypoxia (ortholog); ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Brain-Lung-Thyroid Syndrome (ortholog); genetic disease (ortholog); FOUND IN Golgi-associated vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sec1 family domain-containing protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21531,953,881 - 32,060,885 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,170,383 - 31,277,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01411,401,378 - 11,508,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11429,602,185 - 29,709,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,602,241 - 29,709,133 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SCFD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21531,953,881 - 32,060,885 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,170,383 - 31,277,398 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01411,401,378 - 11,508,418 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11429,602,185 - 29,709,133 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,602,241 - 29,709,133 (+)Ensemblpanpan1.1panPan2
SCFD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381430,622,254 - 30,735,850 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1430,622,291 - 30,737,694 (+)EnsemblGRCh38hg38GRCh38
GRCh371431,091,460 - 31,205,056 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,161,272 - 30,274,769 (+)NCBINCBI36Build 36hg18NCBI36
Build 341430,161,271 - 30,274,769NCBI
Celera1410,957,301 - 11,070,796 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,209,016 - 11,322,601 (+)NCBIHuRef
CHM1_11431,090,992 - 31,204,539 (+)NCBICHM1_1
T2T-CHM13v2.01424,820,073 - 24,933,666 (+)NCBIT2T-CHM13v2.0
Scfd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,424,296 - 51,496,887 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,424,293 - 51,496,884 (+)EnsemblGRCm39 Ensembl
GRCm381251,377,513 - 51,450,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,377,510 - 51,450,101 (+)EnsemblGRCm38mm10GRCm38
MGSCv371252,478,567 - 52,551,083 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,299,200 - 52,371,716 (+)NCBIMGSCv36mm8
Celera1252,670,007 - 52,746,143 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
Scfd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,531,225 - 74,609,463 (+)NCBIGRCr8
mRatBN7.2668,795,810 - 68,874,076 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,795,878 - 68,874,078 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,231,006 - 69,310,933 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,537,662 - 69,617,588 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,977,140 - 69,057,067 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,124,408 - 72,202,703 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,124,417 - 72,202,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,688,247 - 81,766,841 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,453,366 - 71,532,347 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,456,491 - 71,535,473 (+)NCBI
Celera667,685,656 - 67,762,975 (+)NCBICelera
Cytogenetic Map6q22NCBI
Scfd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,805,909 - 29,903,208 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,805,909 - 29,903,208 (-)NCBIChiLan1.0ChiLan1.0
SCFD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.189,970,724 - 10,077,123 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl89,970,790 - 10,077,122 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha89,897,070 - 10,003,576 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,071,833 - 10,178,235 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,071,847 - 10,178,223 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.189,750,624 - 9,856,891 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.089,831,913 - 9,938,667 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,108,002 - 10,214,379 (+)NCBIUU_Cfam_GSD_1.0
Scfd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864041,904,284 - 41,995,811 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,410,269 - 5,501,498 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,410,219 - 5,501,687 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCFD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,712,773 - 68,851,008 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,694,579 - 68,851,055 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,405,676 - 73,475,796 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Scfd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248201,614,884 - 1,714,020 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000062668   ⟹   ENSPPAP00000039756
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1429,602,241 - 29,709,133 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062674   ⟹   ENSPPAP00000039762
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1429,607,786 - 29,708,929 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062676   ⟹   ENSPPAP00000039764
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1429,608,121 - 29,614,862 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000062681   ⟹   ENSPPAP00000039769
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1429,610,433 - 29,614,750 (+)Ensembl
RefSeq Acc Id: XM_003821215   ⟹   XP_003821263
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21531,953,881 - 32,060,885 (+)NCBI
NHGRI_mPanPan11431,170,386 - 31,277,398 (+)NCBI
Mhudiblu_PPA_v01411,401,378 - 11,508,418 (+)NCBI
PanPan1.11429,602,185 - 29,709,133 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003821216   ⟹   XP_003821264
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21531,953,881 - 32,060,885 (+)NCBI
NHGRI_mPanPan11431,170,383 - 31,277,398 (+)NCBI
Mhudiblu_PPA_v01411,401,382 - 11,508,418 (+)NCBI
PanPan1.11429,602,185 - 29,709,133 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008974699   ⟹   XP_008972947
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21531,953,976 - 32,060,885 (+)NCBI
NHGRI_mPanPan11431,170,472 - 31,277,398 (+)NCBI
Mhudiblu_PPA_v01411,401,461 - 11,508,418 (+)NCBI
PanPan1.11429,602,241 - 29,709,133 (+)NCBI
Sequence:
RefSeq Acc Id: XP_003821263   ⟸   XM_003821215
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CNG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003821264   ⟸   XM_003821216
- Peptide Label: isoform X3
- UniProtKB: A0A2R9CCU5 (UniProtKB/TrEMBL),   A0A2R9CNG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008972947   ⟸   XM_008974699
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CNG0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000039764   ⟸   ENSPPAT00000062676
RefSeq Acc Id: ENSPPAP00000039762   ⟸   ENSPPAT00000062674
RefSeq Acc Id: ENSPPAP00000039756   ⟸   ENSPPAT00000062668
RefSeq Acc Id: ENSPPAP00000039769   ⟸   ENSPPAT00000062681


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042546 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062668.1 UniProtKB/TrEMBL
  ENSPPAT00000062674.1 UniProtKB/TrEMBL
  ENSPPAT00000062676.1 UniProtKB/TrEMBL
  ENSPPAT00000062681.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.60 UniProtKB/TrEMBL
  3.40.50.1910 UniProtKB/TrEMBL
  3.40.50.2060 UniProtKB/TrEMBL
InterPro Sec-1-like_dom1 UniProtKB/TrEMBL
  Sec-1-like_dom3a UniProtKB/TrEMBL
  Sec1-like UniProtKB/TrEMBL
  Sec1-like_dom2 UniProtKB/TrEMBL
  Sec1-like_sf UniProtKB/TrEMBL
NCBI Gene SCFD1 ENTREZGENE
PANTHER PTHR11679 UniProtKB/TrEMBL
  SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam Sec1 UniProtKB/TrEMBL
PIRSF VPS45_Sec1 UniProtKB/TrEMBL
Superfamily-SCOP SSF56815 UniProtKB/TrEMBL
UniProt A0A2R9CCU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CD15_PANPA UniProtKB/TrEMBL
  A0A2R9CD20_PANPA UniProtKB/TrEMBL
  A0A2R9CNG0 ENTREZGENE, UniProtKB/TrEMBL