Umod (uromodulin) - Rat Genome Database

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Gene: Umod (uromodulin) Mus musculus
Analyze
Symbol: Umod
Name: uromodulin
RGD ID: 11477
MGI Page MGI
Description: Predicted to enable IgG binding activity. Predicted to be an extracellular matrix structural constituent. Involved in ion homeostasis. Acts upstream of or within with a positive effect on protein phosphorylation. Acts upstream of or within several processes, including inorganic ion homeostasis; kidney development; and response to bacterium. Located in several cellular components, including apical plasma membrane; endoplasmic reticulum; and extracellular space. Is expressed in urinary system. Used to study familial juvenile hyperuricemic nephropathy and kidney disease. Human ortholog(s) of this gene implicated in familial juvenile hyperuricemic nephropathy. Orthologous to human UMOD (uromodulin).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC14034; Tamm-Horsfall glycoprotein; Tamm-Horsfall protein; tamm-Horsfall urinary glycoprotein; THP; ureh; Urehd; Urehd1; urehr4; uromu; uromucoid
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,061,931 - 119,078,485 (-)NCBIGRCm39mm39
GRCm39 Ensembl7119,061,934 - 119,078,505 (-)Ensembl
GRCm387119,462,708 - 119,479,262 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7119,462,711 - 119,479,282 (-)EnsemblGRCm38mm10GRCm38
MGSCv377126,606,380 - 126,622,769 (-)NCBIGRCm37mm9NCBIm37
MGSCv367119,254,013 - 119,270,404 (-)NCBImm8
Celera7119,386,384 - 119,402,859 (-)NCBICelera
Cytogenetic Map7F2NCBI
cM Map763.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IMP)
apoptotic signaling pathway  (IMP)
autophagy  (IMP)
calcium ion homeostasis  (IMP)
cellular calcium ion homeostasis  (IMP)
cellular chloride ion homeostasis  (IDA,IMP)
cellular phosphate ion homeostasis  (IMP)
cellular response to unfolded protein  (IMP)
cellular sodium ion homeostasis  (IMP)
chaperone-mediated protein folding  (IMP)
chemical homeostasis  (IMP)
chloride ion homeostasis  (IMP)
citric acid secretion  (IMP)
collecting duct development  (IMP)
connective tissue replacement  (IMP)
creatinine homeostasis  (IMP)
defense response to Gram-negative bacterium  (IMP)
endoplasmic reticulum organization  (IMP)
gene expression  (IMP)
glomerular filtration  (IMP)
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  (ISO)
inflammatory response  (IMP)
ion homeostasis  (IMP)
juxtaglomerular apparatus development  (IMP)
kidney development  (IMP)
leukocyte cell-cell adhesion  (ISO)
lipid metabolic process  (IMP)
loop of Henle development  (IMP)
metanephric ascending thin limb development  (IEP)
metanephric distal convoluted tubule development  (IEP)
metanephric thick ascending limb development  (IEP)
micturition  (IMP)
multicellular organismal homeostasis  (IMP)
multicellular organismal response to stress  (IMP)
neutrophil migration  (IBA,ISO)
organ or tissue specific immune response  (IMP)
peptidyl-threonine phosphorylation  (IMP)
phosphate ion homeostasis  (IMP)
potassium ion homeostasis  (IMP)
protein localization to vacuole  (IMP)
protein phosphorylation  (IDA,IMP)
protein transport into plasma membrane raft  (IMP)
regulation of blood pressure  (IMP)
regulation of protein transport  (IMP)
regulation of urine volume  (IMP)
renal sodium ion absorption  (IDA,IMP)
renal urate salt excretion  (IMP)
renal water homeostasis  (IMP)
response to endoplasmic reticulum stress  (IMP)
response to lipopolysaccharide  (IDA)
response to organic substance  (ISO)
response to unfolded protein  (IMP)
response to water deprivation  (IMP)
response to xenobiotic stimulus  (IMP)
RNA splicing  (IMP)
sodium ion homeostasis  (IMP)
tumor necrosis factor-mediated signaling pathway  (IMP)
ubiquitin-dependent ERAD pathway  (IMP)
urate transport  (IMP)
urea transmembrane transport  (IMP)
water homeostasis  (IMP)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal autophagy  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal bone structure  (IAGP)
abnormal circulating lipid level  (IAGP)
abnormal endoplasmic reticulum morphology  (IAGP)
abnormal juxtaglomerular apparatus morphology  (IAGP)
abnormal kidney morphology  (IAGP)
abnormal kidney papilla morphology  (IAGP)
abnormal loop of Henle ascending limb thick segment morphology  (IAGP)
abnormal papillary duct morphology  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal renal tubule morphology  (IAGP)
abnormal urine homeostasis  (IAGP)
abnormal urine organic anion level  (IAGP)
abnormal urine osmolality  (IAGP)
abnormal urine urea nitrogen level  (IAGP)
crystalluria  (IAGP)
decreased basal metabolism  (IAGP)
decreased body temperature  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IAGP)
decreased bone mineral density  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating ferritin level  (IAGP)
decreased circulating glucose level  (IAGP)
decreased circulating iron level  (IAGP)
decreased circulating phosphate level  (IAGP)
decreased circulating transferrin level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased creatinine clearance  (IAGP)
decreased kidney weight  (IAGP)
decreased percent body fat/body weight  (IAGP)
decreased renal glomerular filtration rate  (IAGP)
decreased susceptibility to hypertension  (IAGP)
decreased systemic arterial systolic blood pressure  (IAGP)
decreased total body fat amount  (IAGP)
decreased urine citrate level  (IAGP)
decreased urine creatinine level  (IAGP)
decreased urine flow rate  (IAGP)
decreased urine osmolality  (IAGP)
decreased urine pH  (IAGP)
decreased urine protein level  (IAGP)
decreased urine sodium level  (IAGP)
decreased urine uric acid level  (IAGP)
dilated kidney collecting duct  (IAGP)
dilated renal glomerular capsule  (IAGP)
glomerulosclerosis  (IAGP)
hydronephrosis  (IAGP)
increased alkaline phosphatase activity  (IAGP)
increased blood osmolality  (IAGP)
increased blood urea nitrogen level  (IAGP)
increased blood uric acid level  (IAGP)
increased circulating alkaline phosphatase level  (IAGP)
increased circulating calcium level  (IAGP)
increased circulating creatinine level  (IAGP)
increased circulating potassium level  (IAGP)
increased creatinine clearance  (IAGP)
increased endoplasmic reticulum stress  (IAGP)
increased fluid intake  (IAGP)
increased food intake  (IAGP)
increased kidney apoptosis  (IAGP)
increased lean body mass  (IAGP)
increased renal glomerular filtration rate  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased urine ammonia level  (IAGP)
increased urine calcium level  (IAGP)
increased urine chloride ion level  (IAGP)
increased urine creatinine level  (IAGP)
increased urine flow rate  (IAGP)
increased urine magnesium level  (IAGP)
increased urine phosphate level  (IAGP)
increased urine potassium level  (IAGP)
increased urine sodium level  (IAGP)
increased urine uric acid level  (IAGP)
isosthenuria  (IAGP)
kidney failure  (IAGP)
kidney inflammation  (IAGP)
nephrocalcinosis  (IAGP)
polyuria  (IAGP)
renal fibrosis  (IAGP)
renal glomerulus cyst  (IAGP)
renal interstitial fibrosis  (IAGP)
renal tubular necrosis  (IAGP)
uremia  (IAGP)
urolithiasis  (IAGP)
weight loss  (IAGP)
References

Additional References at PubMed
PMID:1425357   PMID:3048972   PMID:3356692   PMID:7503239   PMID:7573490   PMID:7842732   PMID:7873609   PMID:9605864   PMID:10322631   PMID:10349636   PMID:10446940   PMID:11042159  
PMID:11076861   PMID:11217851   PMID:11304570   PMID:11675412   PMID:11729236   PMID:11880321   PMID:12212844   PMID:12351183   PMID:12477932   PMID:14665435   PMID:14675051   PMID:14871399  
PMID:15325280   PMID:15327412   PMID:15489334   PMID:15496149   PMID:15522986   PMID:15741608   PMID:15838507   PMID:16049112   PMID:16141072   PMID:16141073   PMID:16571784   PMID:16688192  
PMID:17079272   PMID:17172448   PMID:17251353   PMID:17264314   PMID:17575307   PMID:17634395   PMID:17765678   PMID:17898038   PMID:17943079   PMID:18025791   PMID:18287559   PMID:18375198  
PMID:18495803   PMID:18600340   PMID:18604206   PMID:18618131   PMID:18776146   PMID:18830570   PMID:19000842   PMID:19060336   PMID:19214995   PMID:19692485   PMID:20172860   PMID:20472742  
PMID:20591941   PMID:20843830   PMID:20862291   PMID:21063698   PMID:21081491   PMID:21228114   PMID:21267068   PMID:21343368   PMID:21386911   PMID:21397062   PMID:21737451   PMID:21873635  
PMID:21909718   PMID:21921145   PMID:22117067   PMID:22132988   PMID:22237754   PMID:22451664   PMID:22999937   PMID:23190605   PMID:23360989   PMID:23389456   PMID:23466996   PMID:23573468  
PMID:23748428   PMID:23941548   PMID:24185693   PMID:24205203   PMID:24324041   PMID:24567330   PMID:24594709   PMID:24603431   PMID:24744442   PMID:25030234   PMID:25168025   PMID:25409434  
PMID:25503683   PMID:25556169   PMID:25725069   PMID:25885434   PMID:25993027   PMID:26116666   PMID:27597235   PMID:28193826   PMID:28325753   PMID:28437467   PMID:28527294   PMID:28535371  
PMID:28542220   PMID:28760814   PMID:28785050   PMID:28829050   PMID:28990932   PMID:28992252   PMID:29145399   PMID:29180395   PMID:29237738   PMID:29357410   PMID:29449453   PMID:29459093  
PMID:29595914   PMID:30007527   PMID:30139743   PMID:30216136   PMID:30297523   PMID:30377232   PMID:31444371   PMID:32439764   PMID:32586976   PMID:33197428   PMID:33737325  


Genomics

Comparative Map Data
Umod
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,061,931 - 119,078,485 (-)NCBIGRCm39mm39
GRCm39 Ensembl7119,061,934 - 119,078,505 (-)Ensembl
GRCm387119,462,708 - 119,479,262 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7119,462,711 - 119,479,282 (-)EnsemblGRCm38mm10GRCm38
MGSCv377126,606,380 - 126,622,769 (-)NCBIGRCm37mm9NCBIm37
MGSCv367119,254,013 - 119,270,404 (-)NCBImm8
Celera7119,386,384 - 119,402,859 (-)NCBICelera
Cytogenetic Map7F2NCBI
cM Map763.88NCBI
UMOD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1620,333,051 - 20,356,301 (-)EnsemblGRCh38hg38GRCh38
GRCh381620,333,051 - 20,356,301 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371620,344,373 - 20,364,037 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361620,251,874 - 20,271,538 (-)NCBINCBI36hg18NCBI36
Build 341620,251,874 - 20,271,538NCBI
Celera1619,493,555 - 19,513,244 (-)NCBI
Cytogenetic Map16p12.3NCBI
HuRef1618,881,007 - 18,900,856 (-)NCBIHuRef
CHM1_11620,432,269 - 20,452,397 (-)NCBICHM1_1
Umod
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21173,816,341 - 173,829,681 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1173,816,339 - 173,830,302 (-)Ensembl
Rnor_6.01189,186,027 - 189,199,939 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,186,026 - 189,199,376 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,127,939 - 196,141,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41177,729,212 - 177,742,552 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11177,868,457 - 177,881,798 (-)NCBI
Celera1171,569,071 - 171,582,409 (-)NCBICelera
Cytogenetic Map1q35NCBI
Umod
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554423,985,308 - 3,999,598 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554423,986,936 - 4,001,155 (-)NCBIChiLan1.0ChiLan1.0
UMOD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11620,429,822 - 20,449,266 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1620,430,085 - 20,449,121 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01617,960,456 - 17,980,338 (+)NCBIMhudiblu_PPA_v0panPan3
UMOD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,991,459 - 25,006,735 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,991,459 - 25,006,735 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha626,355,935 - 26,369,584 (+)NCBI
ROS_Cfam_1.0625,145,508 - 25,160,864 (+)NCBI
UMICH_Zoey_3.1624,946,350 - 24,961,702 (+)NCBI
UNSW_CanFamBas_1.0624,841,732 - 24,857,098 (+)NCBI
UU_Cfam_GSD_1.0625,229,622 - 25,244,770 (+)NCBI
Umod
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344117,735,331 - 117,748,196 (-)NCBI
SpeTri2.0NW_0049365015,833,391 - 5,846,021 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UMOD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl325,473,162 - 25,492,283 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1325,473,048 - 25,492,286 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2326,195,083 - 26,205,810 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UMOD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1518,620,927 - 18,641,312 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl518,619,895 - 18,638,719 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606811,265,375 - 11,285,094 (+)NCBIVero_WHO_p1.0
Umod
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247823,639,955 - 3,654,026 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
L33406  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387119,462,996 - 119,463,114UniSTSGRCm38
MGSCv377126,606,510 - 126,606,628UniSTSGRCm37
Celera7119,386,514 - 119,386,632UniSTS
Cytogenetic Map7F1-F2UniSTS
Whitehead/MRC_RH71226.99UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76500000133900000Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718994869119886157Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
13208555Lgth10_mbody length 10 (mouse)752000000126000000Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)757300000134400000Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)762100000121800000Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)762100000124100000Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765600000126900000Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)768200000119900000Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)768200000124600000Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)768200000125400000Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)770300000120900000Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773400000126100000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)775200000122600000Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)775200000122600000Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)779000000137300000Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)781200000127100000Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781600000124600000Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781800000126900000Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)782200000126900000Mouse
27226763Feml20_mfemur length 20, 16 week (mouse)785400000124600000Mouse
1301647Elpt_melevated leptin (mouse)Not determined786850979120851122Mouse
1302062Stheal6_msoft tissue heal 6 (mouse)Not determined787394725121394859Mouse
1301188Heal6_mwound healing/regeneration 6 (mouse)Not determined787394725121394859Mouse
13463473Hbbcq4_mhemoglobin concentration QTL 4 (mouse)787394725121394859Mouse
1301781Capsq3_mcapsaicin sensitivity related QTL 3 (mouse)Not determined787493929119886157Mouse
27226769Tibl12_mtibia length 12, 10 week (mouse)787600000126900000Mouse
27226790Feml15_mfemur length 15, 10 week (mouse)787600000126900000Mouse
1301937Skull10_mskull morphology 10 (mouse)Not determined791883789125883949Mouse
1357664Nba3_mNew Zealand Black autoimmunity 3 (mouse)Not determined791883789125883949Mouse
1300528Ssial3_msusceptibility to sialadenitis 3 (mouse)Not determined793792641127792834Mouse
1301478Eae26_msusceptibility to experimental allergic encephalomyelitis 26 (mouse)Not determined798565687132565775Mouse
13524850Asrq7_macoustic startle response 7 (mouse)798795739132795739Mouse
10412104Tons2_mtongue size 2 (mouse)Not determined7100238481134238481Mouse
11039524Tbbr3_mTrypanosoma brucei brucei response 3 (mouse)7101151499135151620Mouse
1301447Fembm3_mfemoral bone morphometry 3 (mouse)Not determined7101394038135394119Mouse
1357460Vtbt4_mvertebral trabecular bone trait 4 (mouse)Not determined7102094158136094307Mouse
1301105Cfld4_mcystic fibrosis lung disease 4 (mouse)Not determined7102094158136094307Mouse
1300721Cfbw3_mcystic fibrosis body weight 3 (mouse)Not determined7102094158136094307Mouse
4142312Nilac4_mnicotine induced locomotor activity 4 (mouse)Not determined7102885996136886157Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105651440139651588Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105750785139750785Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7110108163144108163Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7110108163144108163Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7110108163144108163Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7111365511145365612Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7111365511145365612Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111564398145441459Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111564398145441459Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111564398145441459Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112950524145441459Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7113321003145441459Mouse
38501072Stsl7_mSalmonella typhimurium susceptibility locus 7 (mouse)7116100000128900000Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7117032360145441459Mouse
15092059Wogrme1_mweek one growth rate, maternal effect 1 (mouse)7117600000134500000Mouse
11059561Lmr21a_mleishmaniasis resistance 21a (mouse)7118151499128365612Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7119094158144844577Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:164
Count of miRNA genes:148
Interacting mature miRNAs:156
Transcripts:ENSMUST00000033263
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000033263   ⟹   ENSMUSP00000033263
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,061,936 - 119,078,478 (-)Ensembl
GRCm38.p6 Ensembl7119,462,713 - 119,479,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207261   ⟹   ENSMUSP00000147128
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,076,504 - 119,078,505 (-)Ensembl
GRCm38.p6 Ensembl7119,477,281 - 119,479,282 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207378   ⟹   ENSMUSP00000147039
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,071,603 - 119,077,436 (-)Ensembl
GRCm38.p6 Ensembl7119,472,380 - 119,478,213 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207460   ⟹   ENSMUSP00000146628
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,076,203 - 119,078,330 (-)Ensembl
GRCm38.p6 Ensembl7119,476,980 - 119,479,107 (-)Ensembl
RefSeq Acc Id: ENSMUST00000207729
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,076,176 - 119,077,536 (-)Ensembl
GRCm38.p6 Ensembl7119,476,953 - 119,478,313 (-)Ensembl
RefSeq Acc Id: ENSMUST00000209095   ⟹   ENSMUSP00000146652
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl7119,061,934 - 119,078,478 (-)Ensembl
GRCm38.p6 Ensembl7119,462,711 - 119,479,255 (-)Ensembl
RefSeq Acc Id: NM_001278605   ⟹   NP_001265534
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397119,061,931 - 119,078,485 (-)NCBI
GRCm387119,462,708 - 119,479,262 (-)NCBI
Celera7119,386,226 - 119,402,866 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009470   ⟹   NP_033496
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397119,061,931 - 119,078,485 (-)NCBI
GRCm387119,462,708 - 119,479,262 (-)NCBI
MGSCv377126,606,380 - 126,622,769 (-)RGD
Celera7119,386,226 - 119,402,866 (-)NCBI
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033496   ⟸   NM_009470
- Peptide Label: preproprotein
- UniProtKB: Q91X17 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001265534   ⟸   NM_001278605
- Peptide Label: preproprotein
- UniProtKB: Q91X17 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000033263   ⟸   ENSMUST00000033263
RefSeq Acc Id: ENSMUSP00000147128   ⟸   ENSMUST00000207261
RefSeq Acc Id: ENSMUSP00000146628   ⟸   ENSMUST00000207460
RefSeq Acc Id: ENSMUSP00000147039   ⟸   ENSMUST00000207378
RefSeq Acc Id: ENSMUSP00000146652   ⟸   ENSMUST00000209095
Protein Domains
EGF-like   ZP

Promoters
RGD ID:8665377
Promoter ID:EPDNEW_M10720
Type:multiple initiation site
Name:Umod_1
Description:Mus musculus uromodulin , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387119,479,177 - 119,479,237EPDNEW
RGD ID:6848876
Promoter ID:MM_TRO:9167
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:MTR005638.7.3098.4
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367126,620,176 - 126,620,676 (-)MPROMDB
RGD ID:6842304
Promoter ID:MM_KWN:52465
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ENSMUST00000033263,   UC009JLC.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367126,622,426 - 126,622,926 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102674 AgrOrtholog
Ensembl Genes ENSMUSG00000030963 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000033263 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000146628 UniProtKB/TrEMBL
  ENSMUSP00000146652 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000147039 UniProtKB/TrEMBL
  ENSMUSP00000147128 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033263 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000207261 UniProtKB/TrEMBL
  ENSMUST00000207378 UniProtKB/TrEMBL
  ENSMUST00000207460 UniProtKB/TrEMBL
  ENSMUST00000209095 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.4100 UniProtKB/Swiss-Prot
InterPro EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_CS UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP-C UniProtKB/Swiss-Prot
  ZP_dom UniProtKB/Swiss-Prot
  ZP_dom_CS UniProtKB/Swiss-Prot
KEGG Report mmu:22242 UniProtKB/Swiss-Prot
MGD MGI:102674 ENTREZGENE
NCBI Gene 22242 ENTREZGENE
Pfam EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  hEGF UniProtKB/TrEMBL
  Zona_pellucida UniProtKB/Swiss-Prot
PhenoGen Umod PhenoGen
PRINTS ZPELLUCIDA UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZP_1 UniProtKB/Swiss-Prot
  ZP_2 UniProtKB/Swiss-Prot
SMART EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_CA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00241 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A140LI10_MOUSE UniProtKB/TrEMBL
  A0A140LJ15_MOUSE UniProtKB/TrEMBL
  A0A140LJ95_MOUSE UniProtKB/TrEMBL
  Q91X17 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q3TN64 UniProtKB/Swiss-Prot
  Q3TP60 UniProtKB/Swiss-Prot
  Q62285 UniProtKB/Swiss-Prot