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Gene: Tbxas1 (thromboxane A synthase 1, platelet) Mus musculus
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Symbol: Tbxas1
Name: thromboxane A synthase 1, platelet
Description: Exhibits thromboxane-A synthase activity. Predicted to be involved in cellular chloride ion homeostasis and positive regulation of vasoconstriction. Predicted to localize to the endoplasmic reticulum and integral component of membrane. Human ortholog(s) of this gene implicated in cerebral infarction and platelet-type bleeding disorder 14. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Orthologous to human TBXAS1 (thromboxane A synthase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CYP5; CYP5A1; cytochrome P450 5A1; THAS; thromboxane synthase; thromboxane-A synthase; TS; TXA synthase; TXAS; TXS
Orthologs:
Homo sapiens (human) : TBXAS1 (thromboxane A synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbxas1 (thromboxane A synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbxas1 (thromboxane A synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TBXAS1 (thromboxane A synthase 1)
Canis lupus familiaris (dog) : TBXAS1 (thromboxane A synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbxas1 (thromboxane A synthase 1)
Sus scrofa (pig) : TBXAS1 (thromboxane A synthase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38638,864,159 - 39,084,590 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37638,868,985 - 39,034,578 (+)NCBIGRCm37mm9NCBIm37
MGSCv36638,848,593 - 39,014,186 (+)NCBImm8
Celera638,900,560 - 39,068,678 (+)NCBICelera
Cytogenetic Map6 B1NCBI
cM Map617.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tbxas1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11394
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.