Tbxas1 (thromboxane A synthase 1, platelet) - Rat Genome Database
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Gene: Tbxas1 (thromboxane A synthase 1, platelet) Mus musculus
Analyze
Symbol: Tbxas1
Name: thromboxane A synthase 1, platelet
RGD ID: 11394
Description: Exhibits thromboxane-A synthase activity. Predicted to be involved in cellular chloride ion homeostasis; positive regulation of vasoconstriction; and prostaglandin biosynthetic process. Predicted to localize to endoplasmic reticulum membrane. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Human ortholog(s) of this gene implicated in cerebral infarction and platelet-type bleeding disorder 14. Orthologous to human TBXAS1 (thromboxane A synthase 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CYP; CYP5; CYP5A1; cytochrome P450 5A1; THAS; thromboxane synthase; thromboxane-A synthase; TS; TX; TXA synthase; TXAS; TXS
Orthologs:
Homo sapiens (human) : TBXAS1 (thromboxane A synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tbxas1 (thromboxane A synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbxas1 (thromboxane A synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TBXAS1 (thromboxane A synthase 1)
Canis lupus familiaris (dog) : TBXAS1 (thromboxane A synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbxas1 (thromboxane A synthase 1)
Sus scrofa (pig) : TBXAS1 (thromboxane A synthase 1)
Chlorocebus sabaeus (African green monkey) : TBXAS1 (thromboxane A synthase 1)
Heterocephalus glaber (naked mole-rat) : Tbxas1 (thromboxane A synthase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39638,817,897 - 39,061,524 (+)NCBI
GRCm38638,864,159 - 39,084,590 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl638,875,404 - 39,084,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv37638,868,985 - 39,034,578 (+)NCBIGRCm37mm9NCBIm37
MGSCv36638,848,593 - 39,014,186 (+)NCBImm8
Celera638,900,560 - 39,068,678 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map617.85NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
12-HHTrE  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
7,12-dimethyltetraphene  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
asbestos  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chloroacetaldehyde  (ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (EXP)
dioxygen  (ISO)
disodium selenite  (EXP)
elemental selenium  (EXP)
ferric oxide  (EXP)
folic acid  (EXP)
glycidol  (ISO)
hydrogen peroxide  (ISO)
ifosfamide  (ISO)
kojic acid  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (EXP)
manganese(II) chloride  (ISO)
medroxyprogesterone acetate  (ISO)
methoxamine  (ISO)
methylseleninic acid  (EXP)
monocrotaline  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
paracetamol  (EXP)
parthenolide  (EXP)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
protein kinase inhibitor  (ISO)
quinolone  (ISO)
selenium atom  (EXP)
silicon dioxide  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
succimer  (EXP)
sulfasalazine  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
theophylline  (ISO)
thromboxane B2  (ISO)
titanium dioxide  (EXP)
trimellitic anhydride  (EXP)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)


Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
1. Arii K, etal., Life Sci. 2002 Nov 8;71(25):2983-94.
2. Brady KP, etal., Genome Res 1997 Nov;7(11):1085-93.
3. Hirano T, etal., Surgery. 2001 May;129(5):595-605.
4. Iida T, etal., Pancreas. 1998 Aug;17(2):140-7.
5. Imamura T, etal., Arzneimittelforschung. 2003;53(10):688-94.
6. Jones AE, etal., Am J Physiol Lung Cell Mol Physiol. 2003 Jun;284(6):L1072-81. Epub 2003 Mar 14.
7. Kataoka M, etal., Am J Respir Crit Care Med. 2005 Dec 15;172(12):1575-80. Epub 2005 Sep 28.
8. Keen HL, etal., Am J Hypertens. 1997 Oct;10(10 Pt 1):1125-31.
9. Lianos EA and Bresnahan BA, J Lab Clin Med. 1999 Nov;134(5):478-82.
10. Majed BH and Khalil RA, Pharmacol Rev. 2012 Jul;64(3):540-82. doi: 10.1124/pr.111.004770. Epub 2012 Jun 7.
11. MGD and Homologene mouse data transfer
12. MGD data from the GO Consortium
13. MGD IEA
14. Nagao T, etal., Eur J Pharmacol. 1996 Nov 28;316(1):73-80.
15. Nanji AA, etal., J Pharmacol Exp Ther. 1997 Aug;282(2):1037-43.
16. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
17. OMIM Disease Annotation Pipeline
18. Park SA, etal., BMB Rep. 2009 Apr 30;42(4):200-5.
19. Pipeline to import KEGG annotations from KEGG into RGD
20. Pipeline to import SMPDB annotations from SMPDB into RGD
21. RGD automated import pipeline
22. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. RGD automated import pipeline for gene-chemical interactions
24. Tsutsumi E, etal., Prostaglandins 1997 Jun;53(6):423-31.
25. Xu H, etal., Am J Physiol Gastrointest Liver Physiol. 2005 Feb;288(2):G277-83.
Additional References at PubMed
PMID:7688225   PMID:8889548   PMID:9202154   PMID:9367676   PMID:9545490   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11136972   PMID:11217851   PMID:11415940   PMID:12477932  
PMID:12745259   PMID:14681479   PMID:15010374   PMID:16141072   PMID:16141073   PMID:16919269   PMID:18006634   PMID:19735918   PMID:20383787   PMID:21873635   PMID:24009185   PMID:24821912  
PMID:26974824   PMID:30300909  


Genomics

Comparative Map Data
Tbxas1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39638,817,897 - 39,061,524 (+)NCBI
GRCm38638,864,159 - 39,084,590 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl638,875,404 - 39,084,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv37638,868,985 - 39,034,578 (+)NCBIGRCm37mm9NCBIm37
MGSCv36638,848,593 - 39,014,186 (+)NCBImm8
Celera638,900,560 - 39,068,678 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map617.85NCBI
TBXAS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7139,777,051 - 140,020,325 (+)EnsemblGRCh38hg38GRCh38
GRCh387139,778,242 - 140,020,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377139,478,047 - 139,720,125 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367139,175,421 - 139,366,471 (+)NCBINCBI36hg18NCBI36
Build 347138,982,135 - 139,173,186NCBI
Celera7134,200,105 - 134,441,970 (+)NCBI
Cytogenetic Map7q34NCBI
HuRef7133,772,488 - 134,013,944 (+)NCBIHuRef
CHM1_17139,412,286 - 139,654,615 (+)NCBICHM1_1
CRA_TCAGchr7v27138,807,008 - 139,048,964 (+)NCBI
Tbxas1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0466,624,181 - 66,846,745 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl466,670,618 - 66,846,805 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0466,481,238 - 66,651,613 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4466,502,253 - 66,677,538 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1466,778,382 - 66,953,668 (+)NCBI
Celera462,678,426 - 62,850,218 (+)NCBICelera
Cytogenetic Map4q22NCBI
Tbxas1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554943,160,653 - 3,334,411 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554943,161,032 - 3,321,974 (-)NCBIChiLan1.0ChiLan1.0
TBXAS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17144,255,211 - 144,439,523 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7144,255,211 - 144,439,523 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07131,772,947 - 131,958,647 (+)NCBI
TBXAS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl168,870,284 - 9,023,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1168,870,283 - 9,032,105 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tbxas1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365924,038,163 - 4,192,772 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBXAS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl189,717,292 - 9,886,682 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1189,717,291 - 9,886,699 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21810,223,765 - 10,394,512 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TBXAS1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl21108,628,570 - 108,779,163 (+)Ensembl
ChlSab1.121108,584,458 - 108,779,357 (+)NCBI
Tbxas1
(Heterocephalus glaber - naked mole-rat)
No map positions available.

Position Markers
L18868  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38639,084,439 - 39,084,540UniSTSGRCm38
MGSCv37639,034,438 - 39,034,539UniSTSGRCm37
Celera639,068,538 - 39,068,639UniSTS
Cytogenetic Map6F1-pterUniSTS
Whitehead/MRC_RH6313.64UniSTS
Whitehead/MRC_RH6313.16UniSTS
Whitehead_YAC6 UniSTS
MHAa30g3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38638,948,401 - 38,948,582UniSTSGRCm38
MGSCv37638,898,400 - 38,898,581UniSTSGRCm37
Celera638,929,979 - 38,930,160UniSTS
Cytogenetic Map6F1-pterUniSTS
Whitehead_YAC6 UniSTS
D6Mit222  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38638,957,512 - 38,957,659UniSTSGRCm38
MGSCv37638,907,511 - 38,907,658UniSTSGRCm37
Celera638,939,090 - 38,939,237UniSTS
Cytogenetic Map6F1-pterUniSTS
cM Map615.4UniSTS
Whitehead Genetic67.7UniSTS
Whitehead_YAC6 UniSTS
UniSTS:235418  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38639,084,381 - 39,084,587UniSTSGRCm38
MGSCv37639,034,380 - 39,034,586UniSTSGRCm37
Celera639,068,480 - 39,068,686UniSTS
Cytogenetic Map6F1-pterUniSTS
D6Mit90  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38638,969,475 - 38,969,603UniSTSGRCm38
MGSCv37638,919,474 - 38,919,602UniSTSGRCm37
Celera638,951,055 - 38,951,185UniSTS
Cytogenetic Map6F1-pterUniSTS
cM Map615.4UniSTS
Whitehead Genetic67.7UniSTS
Whitehead_YAC6 UniSTS
Tbxas1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37639,034,362 - 39,034,546UniSTSGRCm37
Celera639,068,462 - 39,068,646UniSTS
Cytogenetic Map6F1-pterUniSTS
cM Map620.5UniSTS
cM Map74.0UniSTS
Tbxas1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38639,084,363 - 39,084,547UniSTSGRCm38
MGSCv37639,034,362 - 39,034,546UniSTSGRCm37
Celera639,068,462 - 39,068,646UniSTS
Cytogenetic Map6F1-pterUniSTS
cM Map620.5UniSTS
L18868  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38639,084,385 - 39,084,515UniSTSGRCm38
MGSCv37639,034,384 - 39,034,514UniSTSGRCm37
Celera639,068,484 - 39,068,614UniSTS
Cytogenetic Map6F1-pterUniSTS
Whitehead/MRC_RH6313.64UniSTS
Whitehead/MRC_RH6313.16UniSTS
Tbxas1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6F1-pterUniSTS
Tbxas1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7A3UniSTS
Cytogenetic Map6F1-pterUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
11353840Bmiq2_mbody mass index QTL 2 (mouse)6450382345314181Mouse
1357481Aaj2_manxiety in A/J 2 (mouse)Not determined6450382348726677Mouse
1357520Axtq2_manxiety QTL 2 (mouse)Not determined6450382348726677Mouse
11353841Bmiq3_mbody mass index QTL 3 (mouse)6450382348726677Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080600000Mouse
1302051Sluc7_msusceptibility to lung cancer 7 (mouse)Not determined6929707543297169Mouse
10043869Cia6a_mcollagen induced arthritis QTL 6a (mouse)Not determined61211797246118070Mouse
1301998Bts2_mbladder tumor susceptibility 2 (mouse)Not determined61275122246751334Mouse
4141749Obrq2_mobesity resistance QTL 2 (mouse)Not determined1275122246751334Mouse
27226726Tibmd7_mtibia midshaft diameter 7, 16 week (mouse)61770000053500000Mouse
1301724Pcd4ts1_mp-glycoprotein positive CD4 T cell subset 1 (mouse)Not determined61773466351734784Mouse
4140989Spqq2_msperm quality QTL 2 (mouse)Not determined1773466351734784Mouse
1301850Fglu_mfasting glucose (mouse)Not determined61773466351734784Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414873387692Mouse
12904940Edlmmq5_mextensor digitorum longus muscle mass QTL 5 (mouse)61963941153639411Mouse
12904943Tammq4_mtibialis anterior muscle mass QTL 4 (mouse)61963941153639411Mouse
12904952Gmmq4_mgastrocnemius muscle mass QTL 4 (mouse)61963941153639411Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268671322775Mouse
10412107Desp4_mdespair 4 (mouse)Not determined62007289554072895Mouse
14700690Ccs6_mcolon cancer susceptibility 6 (mouse)62380000057800000Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62500000080000000Mouse
4141988Obrq3_mobesity resistance QTL 3 (mouse)Not determined2831405962314181Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3172656565726677Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63270000066700000Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3285065078238974Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63389528167895420Mouse
11252142Mom12_mModifier of Min 12 (mouse)63389528167895420Mouse
10043868Cia6b_mcollagen induced arthritis QTL 6b (mouse)Not determined63473466338969603Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63629634770296450Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63647147170471591Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3676447870764478Mouse
14746995Manh60_mmandible shape 60 (mouse)63722567771225677Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:932
Count of miRNA genes:575
Interacting mature miRNAs:701
Transcripts:ENSMUST00000003017, ENSMUST00000159226, ENSMUST00000160963, ENSMUST00000161360, ENSMUST00000161781, ENSMUST00000162521, ENSMUST00000162656
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011241280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017321500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC125327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK139479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW046906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L18868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000003017   ⟹   ENSMUSP00000003017
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,918,980 - 39,084,585 (+)Ensembl
RefSeq Acc Id: ENSMUST00000159226
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,919,005 - 39,029,153 (+)Ensembl
RefSeq Acc Id: ENSMUST00000160963   ⟹   ENSMUSP00000124640
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,941,401 - 39,001,363 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161360
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,983,310 - 39,073,206 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161781
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,919,024 - 39,084,585 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162521   ⟹   ENSMUSP00000125406
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,875,404 - 38,952,973 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162656
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl638,971,865 - 38,983,526 (+)Ensembl
RefSeq Acc Id: NM_011539   ⟹   NP_035669
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,920 - 39,061,513 (+)NCBI
GRCm38638,918,986 - 39,084,579 (+)NCBI
MGSCv37638,868,985 - 39,034,578 (+)RGD
Celera638,900,560 - 39,068,678 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006505876   ⟹   XP_006505939
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,918,278 - 39,061,524 (+)NCBI
GRCm38638,941,343 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505877   ⟹   XP_006505940
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,909 - 39,061,524 (+)NCBI
GRCm38638,918,973 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505878   ⟹   XP_006505941
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,909 - 39,061,524 (+)NCBI
GRCm38638,918,973 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505879   ⟹   XP_006505942
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,909 - 39,059,230 (+)NCBI
GRCm38638,918,973 - 39,082,302 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505880   ⟹   XP_006505943
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,960,249 - 39,061,524 (+)NCBI
GRCm38638,983,309 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006505881   ⟹   XP_006505944
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,908 - 39,014,796 (+)NCBI
GRCm38638,918,971 - 39,037,879 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011241280   ⟹   XP_011239582
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,895,031 - 39,061,524 (+)NCBI
GRCm38638,918,076 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321499   ⟹   XP_017176988
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,817,897 - 39,061,524 (+)NCBI
GRCm38638,864,159 - 39,084,590 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017321500   ⟹   XP_017176989
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39638,888,409 - 39,061,524 (+)NCBI
GRCm38638,911,456 - 39,084,590 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035669   ⟸   NM_011539
- UniProtKB: P36423 (UniProtKB/Swiss-Prot),   Q3UTF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505944   ⟸   XM_006505881
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006505941   ⟸   XM_006505878
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006505942   ⟸   XM_006505879
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006505940   ⟸   XM_006505877
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006505939   ⟸   XM_006505876
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006505943   ⟸   XM_006505880
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_011239582   ⟸   XM_011241280
- Peptide Label: isoform X1
- UniProtKB: P36423 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017176988   ⟸   XM_017321499
- Peptide Label: isoform X1
- UniProtKB: P36423 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017176989   ⟸   XM_017321500
- Peptide Label: isoform X1
- UniProtKB: P36423 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000003017   ⟸   ENSMUST00000003017
RefSeq Acc Id: ENSMUSP00000124640   ⟸   ENSMUST00000160963
RefSeq Acc Id: ENSMUSP00000125406   ⟸   ENSMUST00000162521

Promoters
RGD ID:6840053
Promoter ID:MM_KWN:45645
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Kidney
Transcripts:ENSMUST00000003017,   ENSMUST00000101514,   UC009BLD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36638,869,021 - 38,869,521 (+)MPROMDB
RGD ID:6848040
Promoter ID:MM_ACW:40969
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Kidney
Transcripts:TBXAS1.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36638,890,996 - 38,891,496 (+)MPROMDB
RGD ID:6889378
Promoter ID:EPDNEW_M8140
Type:initiation region
Name:Tbxas1_1
Description:Mus musculus thromboxane A synthase 1, platelet , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8141  EPDNEW_M8142  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38638,919,020 - 38,919,080EPDNEW
RGD ID:6840052
Promoter ID:MM_KWN:45646
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:UC009BLF.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36638,932,936 - 38,933,436 (+)MPROMDB
RGD ID:6889380
Promoter ID:EPDNEW_M8141
Type:initiation region
Name:Tbxas1_3
Description:Mus musculus thromboxane A synthase 1, platelet , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8140  EPDNEW_M8142  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38638,983,309 - 38,983,369EPDNEW
RGD ID:6889382
Promoter ID:EPDNEW_M8142
Type:single initiation site
Name:Tbxas1_2
Description:Mus musculus thromboxane A synthase 1, platelet , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8140  EPDNEW_M8141  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38638,997,655 - 38,997,715EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98497 AgrOrtholog
Ensembl Genes ENSMUSG00000029925 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000003017 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000124640 UniProtKB/TrEMBL
  ENSMUSP00000125406 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000003017 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000160963 UniProtKB/TrEMBL
  ENSMUST00000162521 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21391 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98497 ENTREZGENE
NCBI Gene 21391 ENTREZGENE
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TBXAS1 RGD
PhenoGen Tbxas1 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.4054 ENTREZGENE
UniProt F6SG79_MOUSE UniProtKB/TrEMBL
  P36423 ENTREZGENE
  Q3TRY5_MOUSE UniProtKB/TrEMBL
  Q3UTF0 ENTREZGENE, UniProtKB/TrEMBL
  Q8K320_MOUSE UniProtKB/TrEMBL
  THAS_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P97505 UniProtKB/Swiss-Prot

 



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.