Sts (steroid sulfatase) - Rat Genome Database

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Gene: Sts (steroid sulfatase) Mus musculus
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Symbol: Sts
Name: steroid sulfatase
RGD ID: 11358
MGI Page MGI
Description: Predicted to have arylsulfatase activity. Predicted to be involved in female pregnancy and steroid metabolic process. Predicted to localize to endoplasmic reticulum and integral component of membrane. Is expressed in several structures, including central nervous system; sensory organ; skeleton; skin; and spleen. Human ortholog(s) of this gene implicated in X-linked ichthyosis. Orthologous to human STS (steroid sulfatase); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH 1,2-dimethylhydrazine; ciguatoxin CTX1B; clofibrate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A; ArsC; arylsulfatase C; ASC; steryl-sulfatase; steryl-sulfate sulfohydrolase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X168,856,332 - 169,015,037 (-)NCBIGRCm39mm39
Cytogenetic MapXYF5NCBI
cM MapXY75.0NCBI


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3-bisphospho-D-glyceric acid  (ISO)
2,3-bisphosphoglyceric acid  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxy-5-nitrophenyl hydrogen sulfate  (ISO)
2-hydroxypropanoic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-nitrophenyl hydrogen sulfate  (ISO)
6alpha-methylprednisolone  (ISO)
9-cis-retinoic acid  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
androgen antagonist  (ISO)
androst-5-ene-3beta,17beta-diol  (ISO)
arotinoid acid  (ISO)
atrazine  (ISO)
azathioprine  (ISO)
benzimidazoles  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
butan-1-ol  (ISO)
Butylparaben  (ISO)
carmustine  (ISO)
celecoxib  (ISO)
chlorpromazine  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper(II) sulfate  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
danazol  (ISO)
DDE  (ISO)
Deguelin  (ISO)
dehydroepiandrosterone  (ISO)
dehydroepiandrosterone sulfate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
disodium tetraborate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
equilenin  (ISO)
estrone  (ISO)
estrone 3-sulfate  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (EXP,ISO)
genistein  (ISO)
Goe 6976  (ISO)
graphite  (ISO)
leflunomide  (ISO)
linuron  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
naphthalenes  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP,ISO)
parthenolide  (ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidic acid  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
prednisolone  (ISO)
Pregn-5-ene-3beta,20alpha-diol  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
propranolol  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
rottlerin  (ISO)
SB 203580  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium aurothiomalate  (ISO)
sodium dichromate  (ISO)
stilbenoid  (ISO)
sulfamic acid  (ISO)
tazarotene  (ISO)
tazarotenic acid  (ISO)
thioacetamide  (ISO)
torcetrapib  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
troglitazone  (EXP)
trovafloxacin  (ISO)
undecane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
vincristine  (ISO)
wortmannin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:2899541   PMID:3464202   PMID:3475232   PMID:3478692   PMID:3479751   PMID:3503716   PMID:3858674   PMID:6225698   PMID:6573292   PMID:6574326   PMID:6578171   PMID:7857878  
PMID:7987703   PMID:8673108   PMID:8673109   PMID:8691720   PMID:8899734   PMID:8921399   PMID:9348204   PMID:9678332   PMID:9878259   PMID:10559790   PMID:15962010   PMID:16266699  
PMID:17873295   PMID:19251250   PMID:19749746   PMID:20155394   PMID:20503373   PMID:21723668   PMID:21873635   PMID:22189290   PMID:24457600   PMID:24497646   PMID:24602487   PMID:30060148  
PMID:30550785   PMID:31217279  


Genomics

Comparative Map Data
Sts
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X168,856,332 - 169,015,037 (-)NCBIGRCm39mm39
Cytogenetic MapXYF5NCBI
cM MapXY75.0NCBI
STS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX7,147,237 - 7,804,358 (+)EnsemblGRCh38hg38GRCh38
GRCh38X7,147,290 - 7,354,641 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X7,065,331 - 7,272,682 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X7,147,472 - 7,282,682 (+)NCBINCBI36hg18NCBI36
Build 34X6,997,232 - 7,132,416NCBI
CeleraX11,363,616 - 11,498,571 (+)NCBI
Cytogenetic MapXp22.31NCBI
HuRefX4,994,733 - 5,130,162 (+)NCBIHuRef
CHM1_1X7,096,353 - 7,303,668 (+)NCBICHM1_1
Sts
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X42,225,131 - 42,233,403 (+)NCBI
Rnor_6.0 EnsemblX45,420,596 - 45,428,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X45,420,418 - 45,428,748 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X45,646,021 - 45,654,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X63,915,803 - 63,923,834 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X63,969,271 - 63,977,302 (+)NCBI
CeleraX42,864,036 - 42,872,067 (+)NCBICelera
Cytogenetic MapXq21NCBI
Sts
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554995,180,214 - 5,345,221 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554995,180,451 - 5,347,862 (+)NCBIChiLan1.0ChiLan1.0
STS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X7,015,812 - 7,211,919 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX7,047,017 - 7,207,540 (+)Ensemblpanpan1.1panPan2
STS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X4,396,867 - 4,470,093 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX4,325,665 - 4,467,284 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX4,298,275 - 4,448,414 (+)NCBI
ROS_Cfam_1.0X4,277,781 - 4,430,757 (+)NCBI
UMICH_Zoey_3.1X4,275,666 - 4,403,942 (+)NCBI
UNSW_CanFamBas_1.0X4,310,666 - 4,460,990 (+)NCBI
UU_Cfam_GSD_1.0X4,306,633 - 4,435,218 (+)NCBI
Sts
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049532,971,765 - 3,048,416 (+)NCBI
SpeTri2.0NW_0049366441,328,327 - 1,395,856 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X3,926,027 - 4,076,900 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1Y2,747,102 - 2,828,322 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X4,052,271 - 4,255,004 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STS
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X5,601,746 - 5,813,916 (+)NCBI
ChlSab1.1 EnsemblX5,709,410 - 5,812,224 (+)Ensembl
Sts
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248344,805,556 - 4,975,264 (+)NCBI

Position Markers
Sts  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM MapXY75.0UniSTS
Sts  
Mouse AssemblyChrPosition (strand)SourceJBrowse
cM MapXY75.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_009293   ⟹   NP_033319
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X168,856,332 - 169,015,037 (-)NCBI
Protein Sequences
Protein RefSeqs NP_033319 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB09308 (Get FASTA)   NCBI Sequence Viewer  
  P50427 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_033319   ⟸   NM_009293
- Peptide Label: precursor
- UniProtKB: P50427 (UniProtKB/Swiss-Prot)


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98438 AgrOrtholog
Gene3D-CATH 3.40.720.10 UniProtKB/Swiss-Prot
InterPro Alkaline_phosphatase_core_sf UniProtKB/Swiss-Prot
  Sulfatase_CS UniProtKB/Swiss-Prot
  Sulfatase_N UniProtKB/Swiss-Prot
KEGG Report mmu:20905 UniProtKB/Swiss-Prot
MGD MGI:98438 ENTREZGENE
NCBI Gene 20905 ENTREZGENE
Pfam Sulfatase UniProtKB/Swiss-Prot
PhenoGen Sts PhenoGen
PROSITE SULFATASE_1 UniProtKB/Swiss-Prot
  SULFATASE_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53649 UniProtKB/Swiss-Prot
UniProt P50427 ENTREZGENE, UniProtKB/Swiss-Prot