Igkv4-59 (immunoglobulin kappa variable 4-59) - Rat Genome Database

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Gene: Igkv4-59 (immunoglobulin kappa variable 4-59) Mus musculus
Analyze
Symbol: Igkv4-59
Name: immunoglobulin kappa variable 4-59
RGD ID: 11338434
MGI Page MGI
Description: Predicted to be involved in immune response. Predicted to be active in extracellular space.
Type: gene (Ensembl: IG_V_gene)
RefSeq Status: VALIDATED
Previously known as: EG667683; Gm8760; kk4
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39669,415,202 - 69,415,725 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl669,415,202 - 69,415,741 (-)EnsemblGRCm39 Ensembl
GRCm38669,438,218 - 69,438,741 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl669,438,218 - 69,438,757 (-)EnsemblGRCm38mm10GRCm38
MGSCv37669,388,212 - 69,388,735 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36669,367,788 - 69,368,353 (-)NCBIMGSCv36mm8
Celera671,542,316 - 71,542,839 (-)NCBICelera
Cytogenetic Map6C1NCBI
cM Map631.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:2415605   PMID:2438345   PMID:3100644   PMID:3211160   PMID:10427970   PMID:12477932   PMID:15608191   PMID:21873635  


Genomics

Variants

.
Variants in Igkv4-59
27 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:115
Count of miRNA genes:111
Interacting mature miRNAs:114
Transcripts:ENSMUST00000103354
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_005612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC156953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF045517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ231234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC091738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ372796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M12766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M15591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M17720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000103354   ⟹   ENSMUSP00000100155
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl669,415,202 - 69,415,741 (-)Ensembl
GRCm38.p6 Ensembl669,438,218 - 69,438,757 (-)Ensembl
Reference Protein Sequences
RefSeq Acc Id: ENSMUSP00000100155   ⟸   ENSMUST00000103354
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0B4J1I8-F1-model_v2 AlphaFold A0A0B4J1I8 1-117 view protein structure


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000094006 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000103354.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
MGD MGI:3646808 ENTREZGENE
NCBI Gene Igkv4-59 ENTREZGENE
PANTHER IG KAPPA CHAIN V-VI REGION J539-RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN LIGHT CHAIN UniProtKB/TrEMBL
Pfam V-set UniProtKB/TrEMBL
PhenoGen Igkv4-59 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0B4J1I8_MOUSE UniProtKB/TrEMBL